AND VERIFIED CORRECT
ANSWERS GRADED A+
[LATEST] 100% GUARANTEED
PASS
Thiazolidinediones (TZDs)
Pioglitazone (Actos) - CORRECT ANSWER-Black box warning: Cause or exacerbate congestive
heart failure in some patients; do not use if New York Health Association Class III or IV heart
failure
Contraindications: History of MI, stroke, bladder cancer, type I diabetes, eye or liver problems
Stop if causes dyspnea, weight gain, cough (heart failure)
Atypical antipsychotics
Risperidone (Risperdal)
Olanzapine (Zyprexa)
Quetiapine (Seroquel) - CORRECT ANSWER-High risk of weight gain, metabolic syndrome, type 2
diabetes; monitor weight every 3 months
Black box warning: Higher mortality in elderly patients
Monitor TSH, lipids, blood glucose/A1C, weight/body mass index
, Bisphosphonates
Alendronate (Fosamax)
Risedronate (Actonel) - CORRECT ANSWER-Erosive esophagitis (chest pain with eating,
odonophagia (GERD), dysphagia, heartburn),
Stop immediately if symptoms of esophagitis (chest pain, difficulty swallowing, burning
midback) or jaw pain (osteonecrosis); take alone upon awakening with 8-oz glass water (not
juice) before breakfast; do not lie down for 30 minutes afterward; do not mix with other drugs
Contraindications: Active GI disease (GERD, PUD), CKD, esophageal stricture/varices
Statins
Atorvastatin (Lipitor)
Lovastatin (Mevacor)
Rosuvastatin (Crestor)
Simvastatin (Zocor)
Fluvastatin (Lescol)
Pravastatin (Pravachol)
Pitavastatin (Livalo) - CORRECT ANSWER-Do not mix with grapefruit juice; drug-induced
hepatitis or rhabdomyolysis higher if mixed with azole antifungals
High-dose Zocor (80 mg) has highest risk of rhabdomyolysis (muscle pain/tenderness, muscle
weakness, brown or dark red urine)
Chinese descent: Higher risk myopathy or rhabdomyolysis when taking simvastatin 40 mg/d (or
higher) with niacin
Creatine kinase level goes up