TEST PAPER COMPLETE QUESTIONS AND
CORRECT ANSWERS FULL SOLUTION
GUIDE
●● penicillins
Answer: MOA: inhibit bacterial wall synthesis by binding to and
activating enzymes that are essential for cell wall function
effective against gram positive bacteria
- strep throat
- ear infections
- syphillis
●● cephalosporins
Answer: MOA: inhibit cell wall synthesis
broad spectrum, effective against pos and neg bacteria, later generations
are more effective against gram neg
treat respiratory infections, UTIs, skin infections, bacterial meningitis,
pneumonia
,●● cephalosporin generations
Answer: 1 - cephalexin
2 - cefuroxime
3 - ceftriaxone
4 - cefepime
●● macrolides
Answer: MOA: inhibit bacterial protein synthesis
effective against primarily gram pos but some gram neg
erythromycin, azithromycin, clarithromycin
treat respiratory infections, bronchitis, pna, skin infections, STIs
●● flouroquinolones
Answer: MOA: inhibit bacterial DNA synthesis
broad spectrum +/-
ciprofloxacin, levofloxacin, moxifloxacin
,UTIs, GI infections, respiratory infections, skin infections
Risk of tendon rupture! Last resort abx
●● tetracyclines
Answer: MOA: inhibit bacterial synthesis
broad spectrum +/-
tetracycline, doxycycline, minocycline
acne, respiratory infections, lyme, rocky mountain spotted fever, STIs
don't use in kids <8 y.o. unless RMSF
●● aminoglycosides
Answer: MOA: inhibit bacterial protein synthesis
gram negative bacteria
tobramicin, gentamicin, amikacin
, treat sepsis, pna, UTIs, often in combo with another med
risk of ototoxicity, nephrotoxicity, neuromuscular blockade
●● sulfonamides
Answer: MOA: inhibits synthesis of folic acid in bacteria
gram + and some gram neg
bactrim, sulfamethoxazole
UTIs, ear infections, PNA
●● Live attenuated vaccines
Answer: MMR, varicella, nasal flu, rotavirus, yellow fever, smallpox
can cause fever and rash - normal!
must be given on the same day or at least 4 weeks apart, too close
together can interfere with effectiveness