Imprecise joining
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-As V,D,J sections of DNA join, nucleotides may be added or deleted in
each section
-This changes the reading frame of what started to be identical V, D, J
combinations
,Active Immunity
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Immune system produces antibody or T-lymphocytes specific to antigen
Primary infection
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initial infection
Immunofluorescence: Fluorescent dyes
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1. Fluorescein
2. Rhodamine: Fluorescence or glow under UV light microscope
3. Can be attached to "known antigen" to check for antibody presence or
"known antibody" to check for presence of antigen
Complement system
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, 1. Blood proteins in plasma
2. Bind to "Antigen-Antibody complex": This destroys antigen
3. Has 9 parts C1-C9
Function of the lymphoid organs
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to filter and trap invading pathogens and present them to immune
competent cells
Neutralization
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1. Serum: Possibly containing antibody to virus + known virus
2. If match between antibody in serum & known virus
3. This virus mixed into tissue cell culture: No plaque formation
Fc (constant) region
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"Stem"
Heavy chains only
Same for all antibodies of a certain class
Give this one a try later!
-As V,D,J sections of DNA join, nucleotides may be added or deleted in
each section
-This changes the reading frame of what started to be identical V, D, J
combinations
,Active Immunity
Give this one a try later!
Immune system produces antibody or T-lymphocytes specific to antigen
Primary infection
Give this one a try later!
initial infection
Immunofluorescence: Fluorescent dyes
Give this one a try later!
1. Fluorescein
2. Rhodamine: Fluorescence or glow under UV light microscope
3. Can be attached to "known antigen" to check for antibody presence or
"known antibody" to check for presence of antigen
Complement system
Give this one a try later!
, 1. Blood proteins in plasma
2. Bind to "Antigen-Antibody complex": This destroys antigen
3. Has 9 parts C1-C9
Function of the lymphoid organs
Give this one a try later!
to filter and trap invading pathogens and present them to immune
competent cells
Neutralization
Give this one a try later!
1. Serum: Possibly containing antibody to virus + known virus
2. If match between antibody in serum & known virus
3. This virus mixed into tissue cell culture: No plaque formation
Fc (constant) region
Give this one a try later!
"Stem"
Heavy chains only
Same for all antibodies of a certain class
