What is the first-generation antipsychotic commonly known as Thorazine? - Answers Chlorpromazine
What are the primary symptoms of schizophrenia that first-generation antipsychotics target? -
Answers Positive symptoms
What is the mechanism of action for first-generation antipsychotics? - Answers They block receptors
for norepinephrine, acetylcholine, dopamine, and histamine.
What are extrapyramidal effects (EPS)? - Answers Adverse reactions to antipsychotics that affect
movement, including acute dystonia, tardive dyskinesia, akathisia, and drug-induced parkinsonism.
What is acute dystonia and how is it treated? - Answers A severe muscle spasm that requires
immediate intervention, typically treated with anticholinergics like diphenhydramine.
What is tardive dyskinesia? - Answers A condition characterized by writhing movements, often
requiring discontinuation of the medication.
What is akathisia? - Answers A feeling of inner restlessness and an uncontrollable need to be in
constant motion.
What is neuroleptic malignant syndrome? - Answers A life-threatening reaction to antipsychotic
drugs characterized by muscle rigidity, fever, and autonomic instability.
What are contraindications for using first-generation antipsychotics? - Answers Alcohol withdrawal,
bone marrow suppression, CNS disorders, pregnancy, and lactation.
What are the second-generation antipsychotics mentioned? - Answers Risperidone, olanzapine, and
quetiapine.
What is the action of second-generation antipsychotics? - Answers They block dopamine and
serotonin receptors.
What are common adverse effects of second-generation antipsychotics? - Answers Weight gain,
dyslipidemia, and increased prolactin levels leading to gynecomastia.
What is the Abnormal Involuntary Movement Scale (AIMS)? - Answers A tool used to assess
involuntary movements in patients taking antipsychotics.
What is the purpose of disulfiram (Antabuse) in addiction treatment? - Answers To create an adverse
reaction to alcohol consumption, thereby discouraging drinking.
What are the main actions of benzodiazepines in detox treatment? - Answers To prevent seizures and
reduce anxiety during withdrawal.
What is the role of naltrexone in addiction treatment? - Answers To block the effects of endogenous
opiates and reduce cravings.
What are the potential side effects of clonidine in opioid withdrawal? - Answers CNS depression, dry
mouth, and severe rebound hypertension if not tapered.
What is buprenorphine used for? - Answers Management of opioid withdrawal and relapse
prevention.
What is the risk associated with clozapine? - Answers Risk of fatal agranulocytosis, requiring baseline
WBC monitoring.
What should be monitored when a patient is on antipsychotics? - Answers Vital signs, mental status,
and signs of EPS or tardive dyskinesia.
What is the recommended administration route for risperidone? - Answers Orally, mixed with juice,
milk, or water.
What is the significance of weight gain in patients taking second-generation antipsychotics? -
Answers It is a common adverse effect that can lead to metabolic syndrome.
What are the nursing actions for a patient receiving disulfiram? - Answers Educate about avoiding
alcohol and monitor for adverse reactions.
What is the treatment for pseudoparkinsonism caused by antipsychotics? - Answers Anticholinergic
medications like benztropine.