MICB 4131 QUIZ 2 QUESTIONS WELLL ANSWERED LATEST UPDATE 2026
TNF-alpha - Answers macrophage, NK, T cells;
promotes inflammation, vasodilation
IFN-beta - Answers All cells; induces antiviral state, increases MHC I expression
IL-2 - Answers Tc cells; T and B cell proliferation
IL-4 - Answers Th2 cells; promotes Th2 differentiation, isotype switch to IgE
IL-5 - Answers TH2 cells, stimulate growth and differentiation of eosinophils
TGF-beta - Answers T cells, macrophages; inhibits T/B cell proliferation, promotes isotype IgA switch
IFN-y (gamma) - Answers Th1, CD8+ cells; Activates macrophages, increases MHC I/II expression
Immunoglobulin Family - Answers M-CSF, IL-18, IL-1
Chemokine Receptors - Answers IL-8, RANTES, MIP-1
B-Subunit - Answers GM-CSF, IL-3, IL-5
Y-Subunit - Answers IL-2, IL-15 and IL-7
gp130 Subunit - Answers IL-6, IL-11, CNTF, LIF/OSM
AID Protein - Answers Promotes isotype switching of heavy chain
IgM - Answers Primary antibody, identical to BCR, secreted as pentamer
IgD - Answers Present on mature B cell
IgA - Answers dimeric antibody found in body secretions
IL-7 - Answers Proliferation of pre-B & pre-T cells
RAG1/2 - Answers Recombination activating gene for B cell recombination
CD19 - Answers B Cell development signaling protein
PAX-5 - Answers Transcription factor that induces other B cell specific genes
VpreB/λ5 - Answers Surrogate light chain that tests newly formed heavy chains
FcR receptors - Answers Antibody receptors that trigger signaling, Ab transport and/or endocytosis
TNF-alpha - Answers macrophage, NK, T cells;
promotes inflammation, vasodilation
IFN-beta - Answers All cells; induces antiviral state, increases MHC I expression
IL-2 - Answers Tc cells; T and B cell proliferation
IL-4 - Answers Th2 cells; promotes Th2 differentiation, isotype switch to IgE
IL-5 - Answers TH2 cells, stimulate growth and differentiation of eosinophils
TGF-beta - Answers T cells, macrophages; inhibits T/B cell proliferation, promotes isotype IgA switch
IFN-y (gamma) - Answers Th1, CD8+ cells; Activates macrophages, increases MHC I/II expression
Immunoglobulin Family - Answers M-CSF, IL-18, IL-1
Chemokine Receptors - Answers IL-8, RANTES, MIP-1
B-Subunit - Answers GM-CSF, IL-3, IL-5
Y-Subunit - Answers IL-2, IL-15 and IL-7
gp130 Subunit - Answers IL-6, IL-11, CNTF, LIF/OSM
AID Protein - Answers Promotes isotype switching of heavy chain
IgM - Answers Primary antibody, identical to BCR, secreted as pentamer
IgD - Answers Present on mature B cell
IgA - Answers dimeric antibody found in body secretions
IL-7 - Answers Proliferation of pre-B & pre-T cells
RAG1/2 - Answers Recombination activating gene for B cell recombination
CD19 - Answers B Cell development signaling protein
PAX-5 - Answers Transcription factor that induces other B cell specific genes
VpreB/λ5 - Answers Surrogate light chain that tests newly formed heavy chains
FcR receptors - Answers Antibody receptors that trigger signaling, Ab transport and/or endocytosis
