Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
TEST BANK
Clinical Immunology and Serology A Laboratory
Perspective
Christine Dorresteyn Stevens , Linda E. Miller
4th Edition
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
Table of Contents
I. Nature of the Immune System
1. Introduction to Immunity and the Immune System
2. Innate Immunity
3. Nature of Antigens and the Major Histocompatibility Complex
4. Adaptive Immunity
5. Antibody Structure and Function
6. Cytokines
7. The Complement System
II. Basic Immunological Procedures
8. Safety and Quality Management
9. Principles of Serological Testing
10. Precipitation and Agglutination Reactions
11. Labeled Immunoassays
12. Molecular Diagnostic Techniques
13. Flow Cytometry and Laboratory Automation
III. Immune Disorders
14. Hypersensitivity
15. Autoimmunity
16. Transplantation Immunology
17. Tumor Immunology
18. Immunoproliferative Diseases
19. Immunodeficiency Diseases
IV. Serological and Molecular Diagnosis of Infectious Disease
20. Serological and Molecular Detection of Bacterial Infections
21. Spirochete Diseases
22. Serological and Molecular Diagnosis of Parasitic and Fungal Infections
23. Serology and Molecular Detection of Viral Infections
24. Laboratory Diagnosis of HIV Infection
25. Immunization and Vaccines
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
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Chapter 1. Introduction to Immunity and the Immune System
Multiple Choice
1. Eosinophils are involved in the immune response against:
A. viruses.
B. intracellular bacteria.
C. parasites that cannot be phagocytized.
D. extracellular bacteria.
ANS: C
2. Which of the following are components of both innate and adaptive
immune responses?
A. Immunoglobulins
B. T helper cells
C. Macrophages
D. B cells
ANS : C
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
3. The process by which leukocytes are attracted to a specific area by
chemical messengers is called:
A. diapedesis.
B. degranulation.
C. chemotaxis.
D. opsonization.
ANS: C
4. Which of the following is a characteristic of natural killer cells?
A. They mature in the thymus.
B. They are smaller than B and T cells.
C. They are a type of lymphocyte.
D. They are part of the adaptive immune system.
ANS: C
5. Which of the following best describes diapedesis?
2 of 197 Page 2 Page 2 of 197
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
A. Movement toward increasing concentrations of a cytokine
B. Attachment of immunoglobulin to target cells
C. Movement through blood vessel walls as cells exit the circulation
D. Engulfment of target cells
ANS: C
6. The most effective phagocytic and antigen-presenting cell is the:
A. neutrophil.
B. monocyte.
C. dendritic cell.
D. macrophage.
ANS: C
7. Which of the following is characteristic of natural immunity?
A. It involves memory.
B. T lymphocytes play a major role.
C. It involves specificity.
D. Mechanisms are always present and fully functional.
ANS : D
3 of 197 Page 3 Page 3 of 197
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
8. All of the following cells are considered part of natural immunity
EXCEPT:
A. eosinophils.
B. B lymphocytes.
C. monocytes.
D. neutrophils.
ANS : B
9. Where does the specific immune response to a foreign antigen mainly
occur?
A. Lymph nodes
B. Blood
C. Bone marrow
D. Skin
ANS: A
10. Which white cell in the peripheral blood migrates into tissue to
become a macrophage?
A. Eosinophil
B. Basophil
C. Neutrophil
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
D. Monocyte
ANS: D
11. A white blood cell that is 16 to 18 micrometers in diameter, has a
horseshoe-shaped nucleus, and is capable of phagocytosis is a:
A. neutrophil.
B. eosinophil.
C. basophil.
D. monocyte.
ANS: D
12. Pasteur's discovery that older bacterial cultures would not cause
disease in chickens but would protect them from subsequent infection
with more virulent strains is an example of:
A. attenuated vaccine.
B. natural immunity.
C. passive immunity.
D. cross-immunity.
ANS: A
13. Antibodies are secreted by:
A. plasma cells.
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
B. B cells.
C. T cells.
D. dendritic cells.
ANS: A
14. Which of the following is characteristic of mucosal-associated
lymphoid tissue?
A. It is one of the primary lymphoid organs.
B. It clears pathogens from the bloodstream.
C. It includes the tonsils and the appendix.
D. It includes the liver and spleen.
ANS: C
15. Acquired (adaptive) immunity can be characterized as:
A. nonspecifically activated.
B. immediately responsive.
C. neutrophil dependent.
D. involving memory.
ANS: D
6 of 197 Page 6 Page 6 of 197
TEST BANK
Clinical Immunology and Serology A Laboratory
Perspective
Christine Dorresteyn Stevens , Linda E. Miller
4th Edition
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
Table of Contents
I. Nature of the Immune System
1. Introduction to Immunity and the Immune System
2. Innate Immunity
3. Nature of Antigens and the Major Histocompatibility Complex
4. Adaptive Immunity
5. Antibody Structure and Function
6. Cytokines
7. The Complement System
II. Basic Immunological Procedures
8. Safety and Quality Management
9. Principles of Serological Testing
10. Precipitation and Agglutination Reactions
11. Labeled Immunoassays
12. Molecular Diagnostic Techniques
13. Flow Cytometry and Laboratory Automation
III. Immune Disorders
14. Hypersensitivity
15. Autoimmunity
16. Transplantation Immunology
17. Tumor Immunology
18. Immunoproliferative Diseases
19. Immunodeficiency Diseases
IV. Serological and Molecular Diagnosis of Infectious Disease
20. Serological and Molecular Detection of Bacterial Infections
21. Spirochete Diseases
22. Serological and Molecular Diagnosis of Parasitic and Fungal Infections
23. Serology and Molecular Detection of Viral Infections
24. Laboratory Diagnosis of HIV Infection
25. Immunization and Vaccines
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
N
OORLC
OLG
TIN
Y
EIS
C
ATA
NLB
DAIS
M
NEM
KRUFON
OLO
R
OLG
C
OYLGIN
A
YIL
C
AAA
NBLDOIS
M
REM
AR
TUO
NLR
OO
YLGO
PYG
EA
R
YSLAP
ANE
BDC
OS
TRIEA
VR
TEO
,
Chapter 1. Introduction to Immunity and the Immune System
Multiple Choice
1. Eosinophils are involved in the immune response against:
A. viruses.
B. intracellular bacteria.
C. parasites that cannot be phagocytized.
D. extracellular bacteria.
ANS: C
2. Which of the following are components of both innate and adaptive
immune responses?
A. Immunoglobulins
B. T helper cells
C. Macrophages
D. B cells
ANS : C
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
3. The process by which leukocytes are attracted to a specific area by
chemical messengers is called:
A. diapedesis.
B. degranulation.
C. chemotaxis.
D. opsonization.
ANS: C
4. Which of the following is a characteristic of natural killer cells?
A. They mature in the thymus.
B. They are smaller than B and T cells.
C. They are a type of lymphocyte.
D. They are part of the adaptive immune system.
ANS: C
5. Which of the following best describes diapedesis?
2 of 197 Page 2 Page 2 of 197
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
A. Movement toward increasing concentrations of a cytokine
B. Attachment of immunoglobulin to target cells
C. Movement through blood vessel walls as cells exit the circulation
D. Engulfment of target cells
ANS: C
6. The most effective phagocytic and antigen-presenting cell is the:
A. neutrophil.
B. monocyte.
C. dendritic cell.
D. macrophage.
ANS: C
7. Which of the following is characteristic of natural immunity?
A. It involves memory.
B. T lymphocytes play a major role.
C. It involves specificity.
D. Mechanisms are always present and fully functional.
ANS : D
3 of 197 Page 3 Page 3 of 197
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
8. All of the following cells are considered part of natural immunity
EXCEPT:
A. eosinophils.
B. B lymphocytes.
C. monocytes.
D. neutrophils.
ANS : B
9. Where does the specific immune response to a foreign antigen mainly
occur?
A. Lymph nodes
B. Blood
C. Bone marrow
D. Skin
ANS: A
10. Which white cell in the peripheral blood migrates into tissue to
become a macrophage?
A. Eosinophil
B. Basophil
C. Neutrophil
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
D. Monocyte
ANS: D
11. A white blood cell that is 16 to 18 micrometers in diameter, has a
horseshoe-shaped nucleus, and is capable of phagocytosis is a:
A. neutrophil.
B. eosinophil.
C. basophil.
D. monocyte.
ANS: D
12. Pasteur's discovery that older bacterial cultures would not cause
disease in chickens but would protect them from subsequent infection
with more virulent strains is an example of:
A. attenuated vaccine.
B. natural immunity.
C. passive immunity.
D. cross-immunity.
ANS: A
13. Antibodies are secreted by:
A. plasma cells.
, Test Bank - Clinical Immunology and Serology A Laboratory Perspective 4th Edition
B. B cells.
C. T cells.
D. dendritic cells.
ANS: A
14. Which of the following is characteristic of mucosal-associated
lymphoid tissue?
A. It is one of the primary lymphoid organs.
B. It clears pathogens from the bloodstream.
C. It includes the tonsils and the appendix.
D. It includes the liver and spleen.
ANS: C
15. Acquired (adaptive) immunity can be characterized as:
A. nonspecifically activated.
B. immediately responsive.
C. neutrophil dependent.
D. involving memory.
ANS: D
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