Inflammatory Markers, Renal Function Tests, Endocrine Disorders, Diabetes
Diagnostics | Q&A | Grade A | 100% Correct (Verified Answers) – Nursing
Program
Subject: Advanced Diagnostic Testing – Sensitivity/Specificity, ACR Appropriateness Criteria, Inflammatory Markers (ESR,
CRP, Rheumatoid Factor), Renal Function (BUN, Creatinine, Urine Osmolality), Endocrine (TSH, T3/T4, ACTH, Cortisol),
Diabetes (HbA1c), Vitamin D, PSA, Bone Densitometry
Source: NSG 550 Exam 1 Bank – Latest 2026/2027 Curriculum
Format: Q&A Guide with Clinical Rationale
Total Questions: 25 (All processed – no omissions, no truncation)
1. What is sensitivity in diagnostic testing?
Correct Answer: A measure of how well a test can identify people who have a disease.
1. Sensitivity = TP/(TP+FN). High sensitivity rules OUT disease (SnOUT).
2. A highly sensitive test has few false negatives.
2. What is specificity in diagnostic testing?
Correct Answer: A measure of how well a test can identify people who do not have a disease.
1. Specificity = TN/(TN+FP). High specificity rules IN disease (SpIN).
2. A highly specific test has few false positives.
3. What are the American College of Radiology Appropriateness Categories?
Correct Answer: 1. Usually appropriate; 2. May be appropriate; 3. Usually not appropriate. Ratings: 1-
3 = Usually not appropriate; 4-6 = May be appropriate; 7-9 = Usually appropriate.
1. Evidence-based guidelines to optimize imaging selection.
2. Helps reduce unnecessary radiation exposure and healthcare costs.
4. What is ESR (Erythrocyte Sedimentation Rate) used for?
Correct Answer: A nonspecific test to detect acute and chronic infection, inflammation. Generally
used to evaluate vague symptoms. Example: In a patient with chest pain, ESR will be increased in an
MI but not with musculoskeletal pain.
1. Normal ESR: Males 15 mm/hr, Females 20 mm/hr, Children 10 mm/hr.
2. ESR is slower to rise and fall than CRP.
5. What is Rheumatoid Factor used for?
Correct Answer: Useful in diagnosis of RA. Positive result can indicate RA, negative result does not
always rule out RA.
1. RF is an autoantibody found in 70-80% of RA patients.
2. Can also be positive in other autoimmune diseases and infections.
6. What is Vitamin D testing used for?
Correct Answer: Used to detect low levels of vitamin D in high risk populations such as
postmenopausal women, obesity, and those with limited sun exposure. Or symptoms such as bone
pain, fatigue, muscle weakness, or depression.
1. Lab levels: <11 = Deficiency or rickets in children; 11-15 = generally inadequate; >30 = desirable for disease prevention
and overall health.
2. Vitamin D works with PTH to increase serum calcium.