POB EXAM 3 SHADWICK ASSESSMENT TEST
PAPER QUESTIONS AND SOLUTIONS
GRADED A+ FULL REVIEW GUIDE
●● Sickle Cell Anemia
Answer: autosomal recessive disorder where blood cells are irregularly
shaped; they can easily clog vessels but they also protect the individual
from malaria
●● Familial Hypercolestorlemia
Answer: incomplete dominant disorder that causes excessive cholesterol
in the blood and leads to cardiovascular disease
●● ABO Blood Types (Pg. 476)
Answer: controlled by the presence of multiple alleles
●● Environmental Influences (Pg. 478)
Answer: factors like nutrition and temperature that can influence the
expression of genetic traits
●● Down Syndrome
,Answer: occurs when an individual inherits an extra copy of
chromosome 21; upward slant of eyes, low muscle tone, some degree of
intellectual disability
●● Color Blindness (Pg. 484)
Answer: X-linked recessive disorder that is more common in males due
to their sex chromosomes
●● Muscular Dystrophy (Pg. 485)
Answer: X-linked recessive disorder characterized by wasting away of
muscles; characterized by waddling gait, frequent falls, and difficulty in
rising; caused by absence of dystrophin protein
●● Turner Syndrome (Pg. 490)
Answer: females with only one X chromosome who are usually short
and may have malformed features
●● Klinefelter Syndrome (Pg. 490)
Answer: males born with two X chromosomes and one Y; symptoms are
so subtle that only around a quarter of the men are diagnosed and
typically not diagnosed until after age 15
●● Poly-X Females (Pg. 490)
, Answer: a female with more than two X chromosomes that does not
typically show an obvious phenotype
●● SCID in relation to Ex Vivo Gene Therapy (Pg. 528)
Answer: bone marrow stem cells are removed from the patient and
infected with a virus that carries the normal gene for the enzyme, the
cells are then returned to the patient
●● Cystic Fibrosis in relation to In Vivo Gene Therapy (Pg. 528)
Answer: the gene needed is sprayed into the nose or delivered to the
lower respiratory tract by an adenovirus vector
●● Cyanobacteria (Pg. 572)
Answer: produce copious amounts of oxygen, contribute to carbon and
nitrogen fixation, and notorious for forming toxic blooms in water
enriched by nutrients
●● Clostridium Botulinum (Pg. 575)
Answer: creates endospores that germinate in the anaerobic conditions
of canned food under the condition that the food isn't heated high
enough when canning; it's one of the most toxic substances on Earth
●● Salmonella (Pg. 575)
PAPER QUESTIONS AND SOLUTIONS
GRADED A+ FULL REVIEW GUIDE
●● Sickle Cell Anemia
Answer: autosomal recessive disorder where blood cells are irregularly
shaped; they can easily clog vessels but they also protect the individual
from malaria
●● Familial Hypercolestorlemia
Answer: incomplete dominant disorder that causes excessive cholesterol
in the blood and leads to cardiovascular disease
●● ABO Blood Types (Pg. 476)
Answer: controlled by the presence of multiple alleles
●● Environmental Influences (Pg. 478)
Answer: factors like nutrition and temperature that can influence the
expression of genetic traits
●● Down Syndrome
,Answer: occurs when an individual inherits an extra copy of
chromosome 21; upward slant of eyes, low muscle tone, some degree of
intellectual disability
●● Color Blindness (Pg. 484)
Answer: X-linked recessive disorder that is more common in males due
to their sex chromosomes
●● Muscular Dystrophy (Pg. 485)
Answer: X-linked recessive disorder characterized by wasting away of
muscles; characterized by waddling gait, frequent falls, and difficulty in
rising; caused by absence of dystrophin protein
●● Turner Syndrome (Pg. 490)
Answer: females with only one X chromosome who are usually short
and may have malformed features
●● Klinefelter Syndrome (Pg. 490)
Answer: males born with two X chromosomes and one Y; symptoms are
so subtle that only around a quarter of the men are diagnosed and
typically not diagnosed until after age 15
●● Poly-X Females (Pg. 490)
, Answer: a female with more than two X chromosomes that does not
typically show an obvious phenotype
●● SCID in relation to Ex Vivo Gene Therapy (Pg. 528)
Answer: bone marrow stem cells are removed from the patient and
infected with a virus that carries the normal gene for the enzyme, the
cells are then returned to the patient
●● Cystic Fibrosis in relation to In Vivo Gene Therapy (Pg. 528)
Answer: the gene needed is sprayed into the nose or delivered to the
lower respiratory tract by an adenovirus vector
●● Cyanobacteria (Pg. 572)
Answer: produce copious amounts of oxygen, contribute to carbon and
nitrogen fixation, and notorious for forming toxic blooms in water
enriched by nutrients
●● Clostridium Botulinum (Pg. 575)
Answer: creates endospores that germinate in the anaerobic conditions
of canned food under the condition that the food isn't heated high
enough when canning; it's one of the most toxic substances on Earth
●● Salmonella (Pg. 575)
