MARYVILLE NURS 615 PAPER 2026
ADVANCED CONTENT REVIEW WITH
ACCURATE SOLUTIONS
◉ What are the pharmacodynamics of carbamazepine (Tegretol)?
Answer: - Auto-metabolizes leading to lower serum levels despite
compliance.
- Half-life 30 hours as single dose, 15 hours when given repeatedly.
◉ What are the Black Box Warnings for carbamazepine (Tegretol)?
Answer: - Stevens-Johnson Syndrome (SJS)
- Toxic Epidermal Necrolysis (TEN)
◉ Carbamazepine (Tegretol) is what type of drug?
Answer: Anticonvulsant drug
◉ What should families be taught regarding the monitoring of
seizure activity?
Answer: - Prevention of seizures
- Patient Safety
,- Quality of life issues
- Do not discontinue medication due to increased risk of seizures
◉ What electrolyte imbalance is noted with the administration of
topiramate (Topamax)?
Answer: Decrease in sodium bicarbonate leading to hyperchloremic
metabolic acidosis.
◉ What are adverse effects of topiramate (Topamax)?
Answer: - Weight loss, especially in higher dose patients
- May affect ability to sweat
◉ What are pregnancy precautions for valproate (Depakote)?
Answer: - Pregnancy Category X
- Teratogen (an agent that causes malformation of an embryo)
◉ What instructions will you provide to a woman who wants to get
pregnant and has a seizure disorder controlled with valproate
(Depakote)?
Answer: - Pregnant women should be advised to switch to another
anticonvulsant during the first trimester, such as levetiracetam
(Keppra), then switch back to volproate (Depakote) in the second
trimester.
, - All anticonvulsants for pregnant women should be monitored by a
high-risk obstetrician.
◉ What are precautions and contraindications for tricyclic
antidepressants?
Answer: - Caution cardiac disease patients (may act as an
antiarrhythmic)
- HTN, tachycardia, and convulsions when used with MAOIs
◉ What are adverse effects of tricyclic antidepressants?
Answer: - Anticholinergic effects (dry mouth, sedation, constipation,
increased appetite, blurred vision, tinnitus, euphoria, and mania)
◉ Phenylzine (Nardil) is an MAOI. What are the precautions and
contraindications?
Answer: - Avoid foods high in tyramine (fermented foods, wine,
alcohol, aged cheeses, yogurt, soy sauce, summer sausage, processed
meats, etc.)
- Avoid St. John's Wort (Serotonin Syndrome)
-Many other drug-drug interactions
◉ How long does it take to clear an MAOI from the body?
Answer: 2 full weeks, 5 weeks before using fluoxetine (Prozac)
ADVANCED CONTENT REVIEW WITH
ACCURATE SOLUTIONS
◉ What are the pharmacodynamics of carbamazepine (Tegretol)?
Answer: - Auto-metabolizes leading to lower serum levels despite
compliance.
- Half-life 30 hours as single dose, 15 hours when given repeatedly.
◉ What are the Black Box Warnings for carbamazepine (Tegretol)?
Answer: - Stevens-Johnson Syndrome (SJS)
- Toxic Epidermal Necrolysis (TEN)
◉ Carbamazepine (Tegretol) is what type of drug?
Answer: Anticonvulsant drug
◉ What should families be taught regarding the monitoring of
seizure activity?
Answer: - Prevention of seizures
- Patient Safety
,- Quality of life issues
- Do not discontinue medication due to increased risk of seizures
◉ What electrolyte imbalance is noted with the administration of
topiramate (Topamax)?
Answer: Decrease in sodium bicarbonate leading to hyperchloremic
metabolic acidosis.
◉ What are adverse effects of topiramate (Topamax)?
Answer: - Weight loss, especially in higher dose patients
- May affect ability to sweat
◉ What are pregnancy precautions for valproate (Depakote)?
Answer: - Pregnancy Category X
- Teratogen (an agent that causes malformation of an embryo)
◉ What instructions will you provide to a woman who wants to get
pregnant and has a seizure disorder controlled with valproate
(Depakote)?
Answer: - Pregnant women should be advised to switch to another
anticonvulsant during the first trimester, such as levetiracetam
(Keppra), then switch back to volproate (Depakote) in the second
trimester.
, - All anticonvulsants for pregnant women should be monitored by a
high-risk obstetrician.
◉ What are precautions and contraindications for tricyclic
antidepressants?
Answer: - Caution cardiac disease patients (may act as an
antiarrhythmic)
- HTN, tachycardia, and convulsions when used with MAOIs
◉ What are adverse effects of tricyclic antidepressants?
Answer: - Anticholinergic effects (dry mouth, sedation, constipation,
increased appetite, blurred vision, tinnitus, euphoria, and mania)
◉ Phenylzine (Nardil) is an MAOI. What are the precautions and
contraindications?
Answer: - Avoid foods high in tyramine (fermented foods, wine,
alcohol, aged cheeses, yogurt, soy sauce, summer sausage, processed
meats, etc.)
- Avoid St. John's Wort (Serotonin Syndrome)
-Many other drug-drug interactions
◉ How long does it take to clear an MAOI from the body?
Answer: 2 full weeks, 5 weeks before using fluoxetine (Prozac)
