Compiled from your uploaded study questions. Correct answers are highlighted.
Question 1
In Crohn’s disease, granulomas are present in the gastrointestinal tract. This feature
distinguishes Crohn’s from ulcerative colitis. What is the underlying pathophysiological
mechanism responsible for granuloma formation?
A. Overexpression of IL-10 leading to an anti-inflammatory response
B. B-cell proliferation causing lymphoid hyperplasia
C. Eosinophilic infiltration due to parasitic infection
D. Th1-mediated chronic inflammation with macrophage activation
Question 2
Crohn’s disease is classified as an inflammatory bowel disease (IBD). Which of the
following best describes the nature of inflammation in Crohn’s disease?
A. Inflammation only in the colon
B. Transmural inflammation affecting the entire thickness of the intestinal
wall
C. Superficial inflammation limited to the mucosa
D. Inflammation confined to the submucosa
Question 3
A 45-year-old male patient presents with recurrent, severe abdominal pain that
worsens after consuming alcohol or eating. The pain is often relieved by leaning
forward. He also describes having fatty, greasy, and oily stools, associated with weight
loss. What condition is most likely responsible for these symptoms?
A. Chronic cholecystitis
B. Peptic ulcer disease
C. Acute pancreatitis
D. Chronic pancreatitis
Question 4
An older adult patient presents with vague abdominal discomfort and unintentional
weight loss. Endoscopy reveals a malignant lesion in the stomach. Biopsy results show
infiltrating, mostly individual tumor cells surrounded by dense fibrosis. What type of