1|Page
NURS 6630 PSYCHOPHARMACOLOGY MIDTERM
EXAM 2 VERSIONS ACTUAL MIDTERM EXAM
SUMMER QRT| MOST RECENT WALDEN
UNIVERSITY
In rare cases, this Atypical Antidepressant is known to cause severe liver
damage: ......ANSWER......nefazodone
Similar to SSRIs, these two Atypical Antidepressants are strong
inhibitors of Serotonin reuptake transporters on the presynaptic
neuron: ......ANSWER......vilazodone and vortioxetine
These two Atypical Antidepressants bind to and stimulate 5-HT1A
receptors: ......ANSWER......vilazodone (partial agonist) and
vortioxetine (full agonist)
Vilazodone or Vortioxetine, which of these Atypical Antidepressants is a
partial agonist?: ......ANSWER......vilazodone
Vilazodone or Vortioxetine, which of these Atypical Antidepressants is a
full agonist?: ......ANSWER......vortioxetine
pg. 1
,2|Page
Since they enhance the effects of Serotonin through two different
mechanisms, these two Atypical Antidepressants can cause serotonin
syndrome: ......ANSWER......vilazodone and vortioxetine
Six common side effects of vilazodone (primarily anticholinergic,
**unique to vilazodone**): ......ANSWER......sedation, blurred vision,
orthostatic hypotension, urinary retention, tachycardia, **weight
gain**
Six common side effects of vortioxetine (primarily anticholinergic,
**unique to vortioxetine**): ......ANSWER......sedation, blurred vision,
orthostatic hypotension, urinary retention, tachycardia, **abnormal
dreams**
This Atypical Antidepressant does not have a serotonergic effect:
......ANSWER......bupropion
This Atypical Antidepressant binds to Norepinephrine and Dopamine
reuptake transporters and inhibits them, leading to increased levels of
5HT and DA in their synaptic clefts: ......ANSWER......bupropion
In addition to SERT and DAT inhibition this Atypical Antidepressant
blocks nicotinic (acetylcholine) receptors: ......ANSWER......bupropion
pg. 2
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Due to inhibition of nicotinic (acetylcholine) receptors, this Atypical
antidepressant is useful in smoking cessation:
......ANSWER......bupropion
This Atypical Antidepressant has the least sexual side effects of all the
antidepressants: ......ANSWER......bupropion
Due to its noradrenergic (excitatory) effects, this Atypical
Antidepressant may cause tachycardia, insomnia, and a lower seizure
threshold: ......ANSWER......bupropion
These two neuron types have abundant Alpha 2 receptors:
......ANSWER......Noradrenergic and Serotonergic
When stimulated Alpha 2 receptors inhibit the activity of the
presynaptic neuron and decrease the release of these two
neurotransmitters: ......ANSWER......Norepinephrine and Serotonin
In addition to SERT and DAT inhibition this Atypical Antidepressant
blocks nicotinic (acetylcholine) receptors: ......ANSWER......bupropion
Due to inhibition of nicotinic (acetylcholine) receptors, this Atypical
antidepressant is useful in smoking cessation:
......ANSWER......bupropion
pg. 3
NURS 6630 PSYCHOPHARMACOLOGY MIDTERM
EXAM 2 VERSIONS ACTUAL MIDTERM EXAM
SUMMER QRT| MOST RECENT WALDEN
UNIVERSITY
In rare cases, this Atypical Antidepressant is known to cause severe liver
damage: ......ANSWER......nefazodone
Similar to SSRIs, these two Atypical Antidepressants are strong
inhibitors of Serotonin reuptake transporters on the presynaptic
neuron: ......ANSWER......vilazodone and vortioxetine
These two Atypical Antidepressants bind to and stimulate 5-HT1A
receptors: ......ANSWER......vilazodone (partial agonist) and
vortioxetine (full agonist)
Vilazodone or Vortioxetine, which of these Atypical Antidepressants is a
partial agonist?: ......ANSWER......vilazodone
Vilazodone or Vortioxetine, which of these Atypical Antidepressants is a
full agonist?: ......ANSWER......vortioxetine
pg. 1
,2|Page
Since they enhance the effects of Serotonin through two different
mechanisms, these two Atypical Antidepressants can cause serotonin
syndrome: ......ANSWER......vilazodone and vortioxetine
Six common side effects of vilazodone (primarily anticholinergic,
**unique to vilazodone**): ......ANSWER......sedation, blurred vision,
orthostatic hypotension, urinary retention, tachycardia, **weight
gain**
Six common side effects of vortioxetine (primarily anticholinergic,
**unique to vortioxetine**): ......ANSWER......sedation, blurred vision,
orthostatic hypotension, urinary retention, tachycardia, **abnormal
dreams**
This Atypical Antidepressant does not have a serotonergic effect:
......ANSWER......bupropion
This Atypical Antidepressant binds to Norepinephrine and Dopamine
reuptake transporters and inhibits them, leading to increased levels of
5HT and DA in their synaptic clefts: ......ANSWER......bupropion
In addition to SERT and DAT inhibition this Atypical Antidepressant
blocks nicotinic (acetylcholine) receptors: ......ANSWER......bupropion
pg. 2
, 3|Page
Due to inhibition of nicotinic (acetylcholine) receptors, this Atypical
antidepressant is useful in smoking cessation:
......ANSWER......bupropion
This Atypical Antidepressant has the least sexual side effects of all the
antidepressants: ......ANSWER......bupropion
Due to its noradrenergic (excitatory) effects, this Atypical
Antidepressant may cause tachycardia, insomnia, and a lower seizure
threshold: ......ANSWER......bupropion
These two neuron types have abundant Alpha 2 receptors:
......ANSWER......Noradrenergic and Serotonergic
When stimulated Alpha 2 receptors inhibit the activity of the
presynaptic neuron and decrease the release of these two
neurotransmitters: ......ANSWER......Norepinephrine and Serotonin
In addition to SERT and DAT inhibition this Atypical Antidepressant
blocks nicotinic (acetylcholine) receptors: ......ANSWER......bupropion
Due to inhibition of nicotinic (acetylcholine) receptors, this Atypical
antidepressant is useful in smoking cessation:
......ANSWER......bupropion
pg. 3
