1. Which cellular function is first affected by hypoxia?
ATP generation
2. Which mechanism causes cell injury in infections?
Activating the host’s immune system
3. Which condition decreases the oxygen-carrying capacity of blood?
Carbon monoxide poisoning
4. Which substance causes cell damage by inhibiting the electron
transport chain?
Cyanide
5. How does acetaminophen cause cell injury?
Formation of toxic metabolites
6. Reduced activity of Na⁺/K⁺-ATPase results in what?
Increased intracellular Na⁺ concentration
7. Deactivation of oxidative phosphorylation leads to what?
Accumulation of lactic acid
8. Which molecule activates the mitochondrial apoptosis pathway?
Cytochrome C
9. Sickle cell mutation demonstrates what survival advantage?
Having one copy provides protection against malaria
10. Which disease is correctly classified?
Cystic fibrosis is a recessive monogenic disorder
11. How is genetic analysis used to personalize cancer treatment?
By analyzing tumor mutations to prescribe targeted therapies
12. When assessing a patient’s genetic risk, what should providers
consider?
Maternal and paternal family history, lifestyle factors, and diagnostic
results