NR 293 ATI PHARMACOLOGY MIDTERM
PRACTICE PAPER 2026 REVIEW SOLVED
QUESTIONS
◉ What are common causes of medication errors according to
Lehne. Answer: Look-alike/sound-alike drugs, decimal errors,
incomplete medication histories, and poor transitions of care.
◉ What is the definition of the therapeutic range?. Answer: The
therapeutic range is the dosage range in which a drug is effective
without causing toxicity.
◉ What are narrow therapeutic index (NTI) drugs?. Answer: NTI
drugs have a small margin for error, meaning small dose changes can
lead to toxicity.
◉ What factors contribute to why drugs may fail or become toxic?.
Answer: Poor adherence, drug-drug interactions, enzyme
induction/inhibition, renal or hepatic decline, disease progression,
and wrong formulation.
◉ What is the significance of first-pass metabolism?. Answer: First-
pass metabolism can significantly affect the bioavailability of a drug
before it reaches systemic circulation.
PRACTICE PAPER 2026 REVIEW SOLVED
QUESTIONS
◉ What are common causes of medication errors according to
Lehne. Answer: Look-alike/sound-alike drugs, decimal errors,
incomplete medication histories, and poor transitions of care.
◉ What is the definition of the therapeutic range?. Answer: The
therapeutic range is the dosage range in which a drug is effective
without causing toxicity.
◉ What are narrow therapeutic index (NTI) drugs?. Answer: NTI
drugs have a small margin for error, meaning small dose changes can
lead to toxicity.
◉ What factors contribute to why drugs may fail or become toxic?.
Answer: Poor adherence, drug-drug interactions, enzyme
induction/inhibition, renal or hepatic decline, disease progression,
and wrong formulation.
◉ What is the significance of first-pass metabolism?. Answer: First-
pass metabolism can significantly affect the bioavailability of a drug
before it reaches systemic circulation.
