AMT MOLECULAR DIAGNOSTICS
TECHNOLOGIST (MDT)
CERTIFICATION EXAM
QUESTIONS AND CORRECT
ANSWERS (GRADE A+) PLUS
RATIONALES 2026 Q&A | INSTANT
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discuss the impact of molecular diagnostics in human disease - answer-More accurate
disease monitoring - allows for early treatment and improved patient care
Determination of most appropriate treatment
Reduction of patient morbidity and mortality
Able to diagnose and prognosis that patient
*** Example someone might have a HER2 gene amplification but we have a great
medication to use despite the fact that this type of breast cancer is aggressive
define molecular diagnostics - answer-- Molecular diagnostics encompasses the use of
molecular biology techniques to expand scientific knowledge of the natural history of
disease
- Can help identify people at risk for acquiring specific diseases and facilitates the
diagnosis of infectious and other human diseases at the nucleic level
- Molecular testing went from being its own thing to being a part of many lab practices
, importance of nucleic acids in the lab - answer--Assay exhibit extreme sensitivity and
specificity (which can be controlled)
-Genotype before phenotype
-Targets can be amplified >10^6 --- assays like a photocopier so we can find the targets
we are interested in
describe utility of molecular pathology in laboratory medicine - answer-- Assays are
developed based on the presence of specific molecular markers
-Diagnostic test -- distinguish variations in human disease
- Prognostic tests -- accurately describe the course of disease
- Therapeutic tests -- predict the response to specific therapies and determine if therapy
is effective
list applications for genomic technologies - answer-Molecular diagnostics is a universal
discipline of laboratory medicine
Genetics - heritable diseases
Oncology - solid tumors
Hematopathology - leukemia and lymphoma
Identity Testing - transplantation and forensics
TECHNOLOGIST (MDT)
CERTIFICATION EXAM
QUESTIONS AND CORRECT
ANSWERS (GRADE A+) PLUS
RATIONALES 2026 Q&A | INSTANT
DOWNLOAD PDF
discuss the impact of molecular diagnostics in human disease - answer-More accurate
disease monitoring - allows for early treatment and improved patient care
Determination of most appropriate treatment
Reduction of patient morbidity and mortality
Able to diagnose and prognosis that patient
*** Example someone might have a HER2 gene amplification but we have a great
medication to use despite the fact that this type of breast cancer is aggressive
define molecular diagnostics - answer-- Molecular diagnostics encompasses the use of
molecular biology techniques to expand scientific knowledge of the natural history of
disease
- Can help identify people at risk for acquiring specific diseases and facilitates the
diagnosis of infectious and other human diseases at the nucleic level
- Molecular testing went from being its own thing to being a part of many lab practices
, importance of nucleic acids in the lab - answer--Assay exhibit extreme sensitivity and
specificity (which can be controlled)
-Genotype before phenotype
-Targets can be amplified >10^6 --- assays like a photocopier so we can find the targets
we are interested in
describe utility of molecular pathology in laboratory medicine - answer-- Assays are
developed based on the presence of specific molecular markers
-Diagnostic test -- distinguish variations in human disease
- Prognostic tests -- accurately describe the course of disease
- Therapeutic tests -- predict the response to specific therapies and determine if therapy
is effective
list applications for genomic technologies - answer-Molecular diagnostics is a universal
discipline of laboratory medicine
Genetics - heritable diseases
Oncology - solid tumors
Hematopathology - leukemia and lymphoma
Identity Testing - transplantation and forensics
