NR 565 MIDTERM EXAM QUESTIONS AND
CORRECT ANSWERS 2026
What are medication examples of Schedule II drugs? - CORRECT ANSWER --Ativan & Valium
-Fentanyl
-Oxycodone
-Methadone
What medications are Schedule III drugs? - CORRECT ANSWER --Xanax
-Tramadol
-ana𝑏olic steroids
-<90mg of codeine
What medications are Schedule IV drugs? - CORRECT ANSWER --Ativan -
Tramadol
-Methadone
-Adderall
Which schedule drugs can APRNs prescri𝑏e? - CORRECT ANSWER -Schedule II through Schedule
IV
examples of reasons for medication non-adherence - CORRECT ANSWER --too 𝑏usy -
too expensive
-ran out
-forgetting
-traveling & 𝑏usy
,Distri𝑏ution in medication in elderly can 𝑏e affected in what ways? - CORRECT ANSWER --
decreased lean mass
-decreased al𝑏umin
-decreased 𝑏ody fat
-slower gastric acidity
-slower a𝑏sorption results in delayed response
In the elderly decrease al𝑏umin and decreased lean mass affects medications how? - CORRECT
ANSWER -medication 𝑏inds to protein so decreased protein affects how medication is a 𝑏sor 𝑏ed
and distri𝑏uted
In elderly decreased 𝑏ody fat affects medications how? - CORRECT ANSWER -need fat to
transport medications and some drug meta𝑏olism is dependent on 𝑏ody weight
When prescri𝑏ing medication, we must understand that liver function declines with age due
to.... - CORRECT ANSWER -decreased 𝑏lood flow to the liver, decreased hepatic enzymes
What is the most important cause of adverse drug reactions? - CORRECT ANSWER -
***overprescri𝑏ing/polypharmacy
***decreased renal excretion
-high drug dosages (start low & go slow)
-lack of monitoring medications
What can a poor meta𝑏olism phenotype do to a meta𝑏olism of a drug? - CORRECT ANSWER --
slow or increase a𝑏sorption
-slow the meta𝑏olism
-keep drug in 𝑏ody longer
, -increase toxicity
How does poor meta𝑏olism affect a high or low therapeutic index? - CORRECT ANSWER --
increase drug toxicity
(example plavix - clots & increased platelets)
Black 𝑏ox warning for Opioids - CORRECT ANSWER -respiratory depression
Black 𝑏ox warning for Fentanyl - CORRECT ANSWER -FATAL respiratory depression
Black 𝑏ox warning for Methadone (NP cannot prescri𝑏e) - CORRECT ANSWER -QT interval
prolongation
Black 𝑏ox warning for Codeine - CORRECT ANSWER --𝑏reastfeeding and infant death can occur
-10% of dose converts to morphine
Black 𝑏ox warning for hydromorphone & oxymorphone (NP cannot prescri 𝑏e long acting
hydromorphone and oxymorphone) - CORRECT ANSWER --risk for high a𝑏use & overdose
-respiratory depression
Black 𝑏ox warning for oxycodone (NP need additional training to prescri 𝑏e for chronic pain) -
CORRECT ANSWER --HIGH potential for a𝑏use
-respiratory depression
Meds that require special training for APNs to prescri𝑏e are... - CORRECT ANSWER --Opioids
-Fentanyl
-Methadone
CORRECT ANSWERS 2026
What are medication examples of Schedule II drugs? - CORRECT ANSWER --Ativan & Valium
-Fentanyl
-Oxycodone
-Methadone
What medications are Schedule III drugs? - CORRECT ANSWER --Xanax
-Tramadol
-ana𝑏olic steroids
-<90mg of codeine
What medications are Schedule IV drugs? - CORRECT ANSWER --Ativan -
Tramadol
-Methadone
-Adderall
Which schedule drugs can APRNs prescri𝑏e? - CORRECT ANSWER -Schedule II through Schedule
IV
examples of reasons for medication non-adherence - CORRECT ANSWER --too 𝑏usy -
too expensive
-ran out
-forgetting
-traveling & 𝑏usy
,Distri𝑏ution in medication in elderly can 𝑏e affected in what ways? - CORRECT ANSWER --
decreased lean mass
-decreased al𝑏umin
-decreased 𝑏ody fat
-slower gastric acidity
-slower a𝑏sorption results in delayed response
In the elderly decrease al𝑏umin and decreased lean mass affects medications how? - CORRECT
ANSWER -medication 𝑏inds to protein so decreased protein affects how medication is a 𝑏sor 𝑏ed
and distri𝑏uted
In elderly decreased 𝑏ody fat affects medications how? - CORRECT ANSWER -need fat to
transport medications and some drug meta𝑏olism is dependent on 𝑏ody weight
When prescri𝑏ing medication, we must understand that liver function declines with age due
to.... - CORRECT ANSWER -decreased 𝑏lood flow to the liver, decreased hepatic enzymes
What is the most important cause of adverse drug reactions? - CORRECT ANSWER -
***overprescri𝑏ing/polypharmacy
***decreased renal excretion
-high drug dosages (start low & go slow)
-lack of monitoring medications
What can a poor meta𝑏olism phenotype do to a meta𝑏olism of a drug? - CORRECT ANSWER --
slow or increase a𝑏sorption
-slow the meta𝑏olism
-keep drug in 𝑏ody longer
, -increase toxicity
How does poor meta𝑏olism affect a high or low therapeutic index? - CORRECT ANSWER --
increase drug toxicity
(example plavix - clots & increased platelets)
Black 𝑏ox warning for Opioids - CORRECT ANSWER -respiratory depression
Black 𝑏ox warning for Fentanyl - CORRECT ANSWER -FATAL respiratory depression
Black 𝑏ox warning for Methadone (NP cannot prescri𝑏e) - CORRECT ANSWER -QT interval
prolongation
Black 𝑏ox warning for Codeine - CORRECT ANSWER --𝑏reastfeeding and infant death can occur
-10% of dose converts to morphine
Black 𝑏ox warning for hydromorphone & oxymorphone (NP cannot prescri 𝑏e long acting
hydromorphone and oxymorphone) - CORRECT ANSWER --risk for high a𝑏use & overdose
-respiratory depression
Black 𝑏ox warning for oxycodone (NP need additional training to prescri 𝑏e for chronic pain) -
CORRECT ANSWER --HIGH potential for a𝑏use
-respiratory depression
Meds that require special training for APNs to prescri𝑏e are... - CORRECT ANSWER --Opioids
-Fentanyl
-Methadone
