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TestBank
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ForEvolutionaryAnalysis5thEditionByJonC. Herron; Scot k9 k 9 k 9 k9
Freeman978032161667Chapter1-20CompleteGuide.
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EvolutionaryAnalysis5th Edition byHerron Jon, Freeman ScottISBN9780321998378 k9ni k9ni k9ni k9ni k9ni k9ni k9ni k9ni k9
Chapter 1-20
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Chapter 1 k9 k 9 k 9 ACase for Evolutionary Thinking: Understanding HIV
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1) Inwhich ofthe following regions has AIDS killedthe largest numberofindividuals?
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A) India
B) Sub-Saharan Africa k9
C) United States k9
D) China
E) UnitedKingdom k9
Answer: B
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k Section: 1.1
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Skill: Knowledge/Comprehension
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2) The HIVvirus contains all ofthe following components except
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A) integrase
B) double-strandedRNA k9
C) single-stranded RNA k9
D) reverse transcriptase k9
E) protease
Answer: B
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Section:
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k 1.19
Skill: Knowledge/Comprehension
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3) The acronym HIV stands for which ofthe following?
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A) humanintercellular virus k9 k9
B) human immune virus k9 k9
C) humanimmunodeficiencyvirus k9 k9
D) human immunityvirus k9 k9
E) humanimmunodeficiencyvector k9 k9
Answer: C k 9
Section: 1.1 k 9
Skill: Knowledge/Comprehension
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4) Which ofthe followingenzymes is responsible fortranscribingviral RNAinto DNA?
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A) RNApolymerase k9
B) reverse transcriptase k9
C) DNApolymerase k9
D) reverse integrase k9
E) RNAduplicase k9
Answer: B
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Section: 1.1
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Skill: Knowledge/Comprehension
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1
,5) The proteins that enable the HIVvirus to bindto cells are typicallyCD4 andCCR5. Onwhat type
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ofcells are these proteins typicallyobserved?
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A) plasma cells k9
B) dendritic cells k9
C) effector helper T cells k9 k9 k9
D) memoryhelper T cells k9 k9 k9
E) bothCandD k9 k9 k9
Answer: E
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Section: 1.1
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Skill: Knowledge/Comprehension
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6) The AIDS phase ofHIVinfectionbegins whenthe concentrationofCD4 T cells inthe blood
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drops below what concentration?
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A) 2,000 cells percubic millimeter k9 k9 k9 k9
B) 1,000 cells percubic millimeter
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C) 500 cells percubic millimeter
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D) 200 cells per cubic millimeter
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E) No CD4Tcellsareobserved.
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Answer: D k 9
Section: 1.1 k 9
Skill: Knowledge/Comprehension
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7) Whichofthe followingdrug categories are usedto treat HIVinfections?
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A) integrase inhibitors k9
B) protease inhibitors k9
C) reverse transcriptase inhibitors k9 k9
D) DNAse inhibitors k9
E) fusioninhibitors k9
Answer: D
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Section: 1.2
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Skill: Knowledge/Comprehension
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8) Coreceptorinhibitors block HIVinfection bypreventing which ofthe following? k9 k9 k9 k9 k9 k9 k9 k9 k9
A) binding ofthe HIV virion onto the plasma membrane k9 k9 k9 k9 k9 k9 k9
B) bindingofthe HIV virion onto the CCR5 receptor k9 k9 k9 k9 k9 k9 k9
C) binding ofthe HIV virion onto the gp120 protein k9 k9 k9 k9 k9 k9 k9
D) degradingthe coreceptor so the virion cannot attach k9 k9 k9 k9 k9 k9 k9
E) bindingofthe HIVviriononto the CD4 receptor k9 k9 k9 k9 k9 k9 k9
Answer: B
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Section: 1.2 k 9
Skill: Application/Analysis
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9) What is the effect ofthe A32 allele ofCCR5 on HIVbinding?
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A) appears onthe surface ofCD4 Tcells, but the HIV virion is unable to infect the host cell
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B) does not appear on the surface ofCD4 T cells
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C) appears onthe surface ofthe CD4 T cells and inactivates the virion upon binding
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D) interferes withbinding ofthe virion to the CD4 receptor protein k9 k9 k9 k9 k9 k9 k9 k9 k9
2
, E) appears onthe surface ofthe CD4 T cells and causes the virionto lyse uponbinding
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Answer: B
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Section: 1.3 k 9
Skill: Application/Analysis
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10) The A32 allele ofCCR5 is foundat the highest frequencyinwhichofthe following
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populations?
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A) Africans
B) Japanese
C) North Americans k9
D) Europeans
E) SouthAmericans k9
Answer: D
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k Section: 1.3
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Skill: Knowledge/Comprehension
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11) HIV-1 is believedto have beentransmittedto humans fromwhichofthefollowing
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organisms?
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A) gorillas
B) sooty mangabeys k9
C) African greenmonkeys k9 k9
D) chimpanzees
E) baboons
Answer: D
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Section:
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k 1.49
Skill: Knowledge/Comprehension
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12) HIV-1 Group Mis responsible for95% ofhuman infections. When is it estimated that HIV-1
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Group M was transferred to humans?
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A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer: C k 9
Section: 1.4 k 9
Skill: Knowledge/Comprehension
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13) Antibodies andkillerT cells recognize HIVorHIV-infectedcells bybindingto short pieces
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ofviral proteins displayed on the virus or the infected host cell. These short pieces ofviral
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proteins are called
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A) coatproteins k9
B) virosomes
C) proteosomes
D) epitopes
E) episomes
Answer: D k 9
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