CHAPTER TWO
PART II
Streptococci spp
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Streptococcus agalactiae
Group B, β-haemolytic streptococci
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Morphology of Strepto. agalactiae
Gram-positive cocci
arranged in pairs and short
chains in clinical
specimens.
Morphologically similar to
Strepto. Pyogenes
They possess a
polysaccharide capsule ,
which is anti-phagocytic.
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Habitat
Strepto. agalactiae are found
as commensals in the:-
1. Genitourinary tract &
2. Lower gastrointestinal tract.
Vaginal carriage rate as high as
40–50% has been observed in
some pregnant women.
More than 50% of infants born
to these mothers through
vaginal delivery are colonized
with Strepto. agalactiae.
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Infections caused by Strepto.
agalactiae
Strepto. agalactiae in neonates can cause either:-
1) Early-onset infections. or
2) Late-onset infections.
1) Early-onset infections.
Early-onset infection is acquired either in utero or from mother’s
vagina during delivery.
The clinical symptoms develop during the first week of life.
The condition is characterized by:-
Septicemia,
Meningitis, or
Pneumonia.
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CONT,,,
The main predisposing factor is :-
Delayed delivery after rupture of membranes – longer
than 18 hours.
Premature babies are at higher risk.
2) Late-onset infection
Late-onset infection is acquired from mother or from
another infant (environment) during 2–12 weeks of life.
The condition manifests as:-
Septicemia and
Meningitis.
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