NURS6630 MIDTERM EXAM 2026
WALDEN UNIVERSITY TEST BANK
REVIEW COMPLETE QUESTIONS
SOLUTIONS A+
◉ This class of antidepressants binds to presynaptic SERT and inhibits
them from reuptake of serotonin to increase levels in the synaptic cleft to
bind with postsysnaptic 5HT2 receptors.
Answer: SSRIs
◉ First line therapy for MDD due to milder side effect profiles.
Answer: SSRIs
◉ Six Common SSRIs.
Answer: citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
◉ Onset of therapeutic benefit from SSRIs.
Answer: 4-6 weeks
◉ In addition to MDD, SSRIs also treat.
Answer: Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
◉ Five Common side effects of SSRIs include.
,Answer: Anxiety, insomnia, GI distress, sexual dysfunction (ED),
SIADH
◉ Severe side effect of SSRIs in children/adolescents under age 25 years
old.
Answer: suicidal ideation
◉ Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.).
Answer: Serotonin Syndrome
◉ Excess accumulation of serotonin resulting in overstimulation of the
nervous system.
Answer: Serotonin Syndrome
◉ Seven symptoms of Serotonin Syndrome.
Answer: Flushing, hyperthermia, agitation, muscle rigidity, seizure,
coma, HYPERreflexia
◉ The treatment for serotonin syndrome.
Answer: Cyproheptadine (5-HT2 receptor antagonist)
◉ Cyproheptadine treats serotonin syndrome by.
Answer: blocking 5-HT2 receptors (serotonin antagonist)
, ◉ When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include.
Answer: Irritability, headaches, and insomnia
◉ Medicine specific side effect of citalopram.
Answer: Prolonged QT interval (normal=0.4.-0.44 seconds)
◉ This SSRI is pregnancy category D due to associations with
congenital heart defects.
Answer: Paroxetine
◉ All SSRIs but paroxetine (D) are pregnancy category.
Answer: C
◉ Three SSRIs that are inhibitors of Cytochrome P450 enzymes.
Answer: fluoxetine, fluvoxamine, and paroxetine
◉ Five common SNRIs include.
Answer: duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
WALDEN UNIVERSITY TEST BANK
REVIEW COMPLETE QUESTIONS
SOLUTIONS A+
◉ This class of antidepressants binds to presynaptic SERT and inhibits
them from reuptake of serotonin to increase levels in the synaptic cleft to
bind with postsysnaptic 5HT2 receptors.
Answer: SSRIs
◉ First line therapy for MDD due to milder side effect profiles.
Answer: SSRIs
◉ Six Common SSRIs.
Answer: citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
◉ Onset of therapeutic benefit from SSRIs.
Answer: 4-6 weeks
◉ In addition to MDD, SSRIs also treat.
Answer: Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
◉ Five Common side effects of SSRIs include.
,Answer: Anxiety, insomnia, GI distress, sexual dysfunction (ED),
SIADH
◉ Severe side effect of SSRIs in children/adolescents under age 25 years
old.
Answer: suicidal ideation
◉ Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.).
Answer: Serotonin Syndrome
◉ Excess accumulation of serotonin resulting in overstimulation of the
nervous system.
Answer: Serotonin Syndrome
◉ Seven symptoms of Serotonin Syndrome.
Answer: Flushing, hyperthermia, agitation, muscle rigidity, seizure,
coma, HYPERreflexia
◉ The treatment for serotonin syndrome.
Answer: Cyproheptadine (5-HT2 receptor antagonist)
◉ Cyproheptadine treats serotonin syndrome by.
Answer: blocking 5-HT2 receptors (serotonin antagonist)
, ◉ When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include.
Answer: Irritability, headaches, and insomnia
◉ Medicine specific side effect of citalopram.
Answer: Prolonged QT interval (normal=0.4.-0.44 seconds)
◉ This SSRI is pregnancy category D due to associations with
congenital heart defects.
Answer: Paroxetine
◉ All SSRIs but paroxetine (D) are pregnancy category.
Answer: C
◉ Three SSRIs that are inhibitors of Cytochrome P450 enzymes.
Answer: fluoxetine, fluvoxamine, and paroxetine
◉ Five common SNRIs include.
Answer: duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
