Immunology Exam 1
2026/2027 | Questions &
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Updated 2026 Questions and Answers
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, T or F: Blood cells and certain tissue cells derive from a True. It's pluripotent & self-renewing (can make many copies of itself)
common hematopoietic stem cell.
Immune cells go through which pathways? Lymphoid and myeloid pathways.
What are examples of granulocytes? neutrophils, basophils, and eosinophils. They are polymorphonuclear leukocytes
that reside in the blood.
What chemical signals drive the path the cell takes to its 1. colony stimulating factor (CSF) - GCSF (granulocyte colony stimulating factor) --
final fate? > drives the production of neutrophils
2. cytokines
3. growth factors
Blood cell development occurs where in the body? fetal liver or spleen, and bone marrow (adults only)
What does lymphoid progenitor differentiate into? 1. B cells
2. T cells
3. Natural Killer (NK) cells
What does myeloid progenitor differentiate into? 1. basophils
2. eosinophils
3. neutrophils
4. mast cells
5. dendritic cells
6. monocytes
What are the primary lymphoid tissues? bone marrow and thymus. Sites where the lymphocytes/leukocytes develop.
What are the secondary lymphoid tissues? sites where lymphocytes are activated to respond to pathogens include the
spleen, lymph nodes, tonsil/adenoids, malt/balt/galt (mucosal/bronchial/gut
associated lymphoid tissues); "dynamic" tissues bc lymphocytes are constantly
arriving and departing & "sampling" the environment in secondary tissue to see if
they need to respond to a pathogen.
What's the significance of lymph nodes? it is where lymphocytes are activated by antigens
Wha'ts the significance of the spleen? it is where lymphocytes are activated by antigens in blood in the white pulp to
cause immune activation (red pulp is the dead/dying RBCs accummulation and
removed from circulation)
Describe the process of how lymphocytes are activated 1. pathogen invading tissue
in the lymph nodes. 2. MO responds by phagogytosing antigen/pathogen
-facilitate inflammatory response
- DC internalize antigen & move to draining lymph
node
3. DC-pathogen, pathogen, pathogen components arrive the lymph node via the
afferent lymphatics.
4. T-cells become activated by the DC that are carrying the antigen to the lymph
node
5. B-cells become activated by the recognition of the pathogen components or
pathogen.
2026/2027 | Questions &
Answers | Study Guide &
Exam Prep
|Graded A+ | Guaranteed
success|
Updated 2026 Questions and Answers
100% Verified Exam Prep and Comprehensive
Rationales
Included
, T or F: Blood cells and certain tissue cells derive from a True. It's pluripotent & self-renewing (can make many copies of itself)
common hematopoietic stem cell.
Immune cells go through which pathways? Lymphoid and myeloid pathways.
What are examples of granulocytes? neutrophils, basophils, and eosinophils. They are polymorphonuclear leukocytes
that reside in the blood.
What chemical signals drive the path the cell takes to its 1. colony stimulating factor (CSF) - GCSF (granulocyte colony stimulating factor) --
final fate? > drives the production of neutrophils
2. cytokines
3. growth factors
Blood cell development occurs where in the body? fetal liver or spleen, and bone marrow (adults only)
What does lymphoid progenitor differentiate into? 1. B cells
2. T cells
3. Natural Killer (NK) cells
What does myeloid progenitor differentiate into? 1. basophils
2. eosinophils
3. neutrophils
4. mast cells
5. dendritic cells
6. monocytes
What are the primary lymphoid tissues? bone marrow and thymus. Sites where the lymphocytes/leukocytes develop.
What are the secondary lymphoid tissues? sites where lymphocytes are activated to respond to pathogens include the
spleen, lymph nodes, tonsil/adenoids, malt/balt/galt (mucosal/bronchial/gut
associated lymphoid tissues); "dynamic" tissues bc lymphocytes are constantly
arriving and departing & "sampling" the environment in secondary tissue to see if
they need to respond to a pathogen.
What's the significance of lymph nodes? it is where lymphocytes are activated by antigens
Wha'ts the significance of the spleen? it is where lymphocytes are activated by antigens in blood in the white pulp to
cause immune activation (red pulp is the dead/dying RBCs accummulation and
removed from circulation)
Describe the process of how lymphocytes are activated 1. pathogen invading tissue
in the lymph nodes. 2. MO responds by phagogytosing antigen/pathogen
-facilitate inflammatory response
- DC internalize antigen & move to draining lymph
node
3. DC-pathogen, pathogen, pathogen components arrive the lymph node via the
afferent lymphatics.
4. T-cells become activated by the DC that are carrying the antigen to the lymph
node
5. B-cells become activated by the recognition of the pathogen components or
pathogen.
