STUDENT C O M P A N I O N
F U N D A M E N T A L S O F
Biochemistry
LIFE AT
THE MOLECULAR
LEVEL
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
Donald Voet Judith G. Voet Charlotte W. Pratt
,This page is intentionally left blank
,STUDENT COMPANION TO ACCOMPANY
FUNDAMENTALS OF
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
Fourth Edition
Akif Uzman
University of Houston
Jerry Johnson
University of Houston
Joseph Eichberg
University of Houston
William Widger
University of Houston
Donald Voet
University of Pennsylvania
Judith G. Voet
Swarthmore College
Charlotte W. Pratt
Seattle, Washington
JOHN WILEY & SONS, INC
, CoverHDesignerHMadelynHLesureHCo
verHIllustrationHNormHChristiansenHC
overHPhotos
(VitruvianHMan):H©HOdysseus/AlamyHandH©HDennisHHallinan/Alamy
MolecularHstructuresHclockwiseHfromHtop:HbasedHonHX-
rayHstructuresHthatHwereHrespectivelyHdeterminedHbyHRichardHDickersonHandHHoraceHDrew,HCaltech;HG
erardHBunick,HUniversityHofHTennessee;HThomasHSteitz,HYaleHUniversity;HAlfonsoHMondragón,HNorthw
esternHUniversity;HVenkiHRamakrishnan,HMRCHLaboratoryHofHMolecularHBiology,HCambridge,HU.K.;HA
ndrewHLeslieHandHJohnHWalker,HMRCHLaboratoryHofHMolecularHBiology,HCambridge,HU.K.
FoundedHinH1807,HJohnHWileyH&HSons,HInc.HhasHbeenHaHvaluedHsourceHofHknowledgeHandHunderstandingH
forHmoreHthanH200Hyears,HhelpingHpeopleHaroundHtheHworldHmeetHtheirHneedsHandHfulfillHtheirHaspirations.
HOurHcompanyHisHbuiltHonHaHfoundationHofHprinciplesHthatHincludeHresponsibilityHtoHtheHcommunitiesHweHs
erveHandHwhereHweHliveHandHwork.HInH2008,HweHlaunchedHaHCorporateHCitizenshipHInitiative,HaHglobalHeff
ortHtoHaddressHtheHenvironmental,Hsocial,Heconomic,HandHethicalHchallengesHweHfaceHinHourHbusiness.HAm
ongHtheHissuesHweHareHaddressingHareHcarbonHimpact,HpaperHspecificationsHandHprocurement,HethicalHcond
uctHwithinHourHbusinessHandHamongHourHvendors,HandHcommunityHandHcharitableHsupport.HForHmoreHinfor
mation,HpleaseHvisitHourHwebsite:Hwww.wiley.com/go/citizenship.
CopyrightH©H2012 JohnHWileyH&HSons,HInc.
AllHrightsHreserved.HNoHpartHofHthisHpublicationHmayHbeHreproduced,HstoredHinHaHretrievalHsystemHorHtran
smittedHinHanyHformHorHbyHanyHmeans,Helectronic,Hmechanical,Hphotocopying,Hrecording,HscanningHorHot
herwise,HexceptHasHpermittedHunderHSectionsH107HorH108HofHtheH1976HUnitedHStatesHCopyrightHAct,Hwit
houtHeitherHtheHpriorHwrittenHpermissionHofHtheHPublisher,HorHauthorizationHthroughHpaymentHofHtheHappr
opriateHper-
copyHfeeHtoHtheHCopyrightHClearanceHCenter,HInc.,H222HRosewoodHDrive,HDanvers,HMAH01923,Hwebsite
Hwww.copyright.com.HRequestsHtoHtheHPublisherHforHpermissionHshouldHbeHaddressedHtoHtheH Permissions
HDepartment,HJohnHWileyH&HSons,HInc.H111HRiverHStreet,HHoboken,HNJH07030-5774,H(201)H748-
6011,HfaxH(201)H748-6008,HwebsiteHhttp://www.wiley.com/go/permissions.
ToHorderHbooksHorHforHcustomerHservice,HpleaseHcallH1-800-CALLHWILEYH(225-5945).
StudentHCompanionH(paperback) ISBN-13H 978-1-1182-1827-3
PrintedHinHtheHUnitedHStatesHofHAmeri
caH10H 9H8H7H 6H5H4H 3H2H1
F U N D A M E N T A L S O F
Biochemistry
LIFE AT
THE MOLECULAR
LEVEL
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
Donald Voet Judith G. Voet Charlotte W. Pratt
,This page is intentionally left blank
,STUDENT COMPANION TO ACCOMPANY
FUNDAMENTALS OF
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
Fourth Edition
Akif Uzman
University of Houston
Jerry Johnson
University of Houston
Joseph Eichberg
University of Houston
William Widger
University of Houston
Donald Voet
University of Pennsylvania
Judith G. Voet
Swarthmore College
Charlotte W. Pratt
Seattle, Washington
JOHN WILEY & SONS, INC
, CoverHDesignerHMadelynHLesureHCo
verHIllustrationHNormHChristiansenHC
overHPhotos
(VitruvianHMan):H©HOdysseus/AlamyHandH©HDennisHHallinan/Alamy
MolecularHstructuresHclockwiseHfromHtop:HbasedHonHX-
rayHstructuresHthatHwereHrespectivelyHdeterminedHbyHRichardHDickersonHandHHoraceHDrew,HCaltech;HG
erardHBunick,HUniversityHofHTennessee;HThomasHSteitz,HYaleHUniversity;HAlfonsoHMondragón,HNorthw
esternHUniversity;HVenkiHRamakrishnan,HMRCHLaboratoryHofHMolecularHBiology,HCambridge,HU.K.;HA
ndrewHLeslieHandHJohnHWalker,HMRCHLaboratoryHofHMolecularHBiology,HCambridge,HU.K.
FoundedHinH1807,HJohnHWileyH&HSons,HInc.HhasHbeenHaHvaluedHsourceHofHknowledgeHandHunderstandingH
forHmoreHthanH200Hyears,HhelpingHpeopleHaroundHtheHworldHmeetHtheirHneedsHandHfulfillHtheirHaspirations.
HOurHcompanyHisHbuiltHonHaHfoundationHofHprinciplesHthatHincludeHresponsibilityHtoHtheHcommunitiesHweHs
erveHandHwhereHweHliveHandHwork.HInH2008,HweHlaunchedHaHCorporateHCitizenshipHInitiative,HaHglobalHeff
ortHtoHaddressHtheHenvironmental,Hsocial,Heconomic,HandHethicalHchallengesHweHfaceHinHourHbusiness.HAm
ongHtheHissuesHweHareHaddressingHareHcarbonHimpact,HpaperHspecificationsHandHprocurement,HethicalHcond
uctHwithinHourHbusinessHandHamongHourHvendors,HandHcommunityHandHcharitableHsupport.HForHmoreHinfor
mation,HpleaseHvisitHourHwebsite:Hwww.wiley.com/go/citizenship.
CopyrightH©H2012 JohnHWileyH&HSons,HInc.
AllHrightsHreserved.HNoHpartHofHthisHpublicationHmayHbeHreproduced,HstoredHinHaHretrievalHsystemHorHtran
smittedHinHanyHformHorHbyHanyHmeans,Helectronic,Hmechanical,Hphotocopying,Hrecording,HscanningHorHot
herwise,HexceptHasHpermittedHunderHSectionsH107HorH108HofHtheH1976HUnitedHStatesHCopyrightHAct,Hwit
houtHeitherHtheHpriorHwrittenHpermissionHofHtheHPublisher,HorHauthorizationHthroughHpaymentHofHtheHappr
opriateHper-
copyHfeeHtoHtheHCopyrightHClearanceHCenter,HInc.,H222HRosewoodHDrive,HDanvers,HMAH01923,Hwebsite
Hwww.copyright.com.HRequestsHtoHtheHPublisherHforHpermissionHshouldHbeHaddressedHtoHtheH Permissions
HDepartment,HJohnHWileyH&HSons,HInc.H111HRiverHStreet,HHoboken,HNJH07030-5774,H(201)H748-
6011,HfaxH(201)H748-6008,HwebsiteHhttp://www.wiley.com/go/permissions.
ToHorderHbooksHorHforHcustomerHservice,HpleaseHcallH1-800-CALLHWILEYH(225-5945).
StudentHCompanionH(paperback) ISBN-13H 978-1-1182-1827-3
PrintedHinHtheHUnitedHStatesHofHAmeri
caH10H 9H8H7H 6H5H4H 3H2H1
