Nsg 3370 Exam 1.0 Questions With
Pathophysiology - ANSWER is the study of functional or physiological change in
the body that result from a disease process
Pharmacology - ANSWER is the study of the biological effects of chemicals on
living organisms
Ischemia - ANSWER is cell damage d/t deficit of O2
Necrosis - ANSWER is dying cells causing further damage d/t cellular
disintegration
Homeostasis - ANSWER is the maintenance of a relatively stable internal
environment regardless of external changes
Body is designed to maintain this table environment
Any deviation from this normal state is disease
Etiology - ANSWER are the causative factors in a particular disease
Therapeutic class - ANSWER is based on therapeutic usefulness in treating
particular diseases or disorders (broad)
Pharmacologic class - ANSWER is based on the way a drug works at the
molecular, tissue, or body system level. Addresses a drug's mechanism of
action (specific)
Mechanism of action - ANSWER is how a drug produces its physiological effect
in the body
Pharmacokinetics - ANSWER is the study of drug movement throughout the
body; explained through absorption, distribution, metabolism, excretion
Absorption - ANSWER is movement from site of administration, across body
membranes, to circulating fluids. Primary pharmacokinetic factor determining
length of time for drug to produce effect
Distribution - ANSWER is the transport of drugs throughout the body
, Metabolism (biotransformation) - ANSWER is the chemical conversion of a drug
so it can be easily removed from the body. **Liver is the primary site
Excretion - ANSWER is how drug gets out of the body. Primary site of excretion
of drugs is the kidneys
What are the divisions of the PNS? - ANSWER autonomic nervous system and
somatic nervous system
What are the primary neurotransmitters of the ANS? - ANSWER Catecholamines
and Acetylcholine (Ach)
What do catecholamines primarily act on? - ANSWER Alpha and Beta receptors
What does Acetylcholine primarily act on? - ANSWER Nicotinic and Muscarinic
receptors
Catecholamines are neurotransmitters of the ... - ANSWER SYMPATHETIC
nervous system
Ach is the neurotransmitter of the... - ANSWER PARASYMPATHETIC nervous
system
The Adrenergic receptor alpha 1 is found... - ANSWER In all sympathetic target
organs except heart
The Adrenergic receptor alpha 2 is found... - ANSWER At presynaptic
adrenergic neuron terminals
*inhibits release of norepinepherine
The Adrenergic receptor beta 1 is found... - ANSWER in the cardiac tissue
-increases the heart rate and increase the
heart's strength of contraction or
contractility.
-increases renin secretion from the kidneys
The Adrenergic receptor beta 2 is found... - ANSWER In all sympathetic target
organs except the heart
*inhibits smooth muscle
What do alpha and beta receptors do? - ANSWER A B C D (alpha causes
constriction, beta causes dilation)
Pathophysiology - ANSWER is the study of functional or physiological change in
the body that result from a disease process
Pharmacology - ANSWER is the study of the biological effects of chemicals on
living organisms
Ischemia - ANSWER is cell damage d/t deficit of O2
Necrosis - ANSWER is dying cells causing further damage d/t cellular
disintegration
Homeostasis - ANSWER is the maintenance of a relatively stable internal
environment regardless of external changes
Body is designed to maintain this table environment
Any deviation from this normal state is disease
Etiology - ANSWER are the causative factors in a particular disease
Therapeutic class - ANSWER is based on therapeutic usefulness in treating
particular diseases or disorders (broad)
Pharmacologic class - ANSWER is based on the way a drug works at the
molecular, tissue, or body system level. Addresses a drug's mechanism of
action (specific)
Mechanism of action - ANSWER is how a drug produces its physiological effect
in the body
Pharmacokinetics - ANSWER is the study of drug movement throughout the
body; explained through absorption, distribution, metabolism, excretion
Absorption - ANSWER is movement from site of administration, across body
membranes, to circulating fluids. Primary pharmacokinetic factor determining
length of time for drug to produce effect
Distribution - ANSWER is the transport of drugs throughout the body
, Metabolism (biotransformation) - ANSWER is the chemical conversion of a drug
so it can be easily removed from the body. **Liver is the primary site
Excretion - ANSWER is how drug gets out of the body. Primary site of excretion
of drugs is the kidneys
What are the divisions of the PNS? - ANSWER autonomic nervous system and
somatic nervous system
What are the primary neurotransmitters of the ANS? - ANSWER Catecholamines
and Acetylcholine (Ach)
What do catecholamines primarily act on? - ANSWER Alpha and Beta receptors
What does Acetylcholine primarily act on? - ANSWER Nicotinic and Muscarinic
receptors
Catecholamines are neurotransmitters of the ... - ANSWER SYMPATHETIC
nervous system
Ach is the neurotransmitter of the... - ANSWER PARASYMPATHETIC nervous
system
The Adrenergic receptor alpha 1 is found... - ANSWER In all sympathetic target
organs except heart
The Adrenergic receptor alpha 2 is found... - ANSWER At presynaptic
adrenergic neuron terminals
*inhibits release of norepinepherine
The Adrenergic receptor beta 1 is found... - ANSWER in the cardiac tissue
-increases the heart rate and increase the
heart's strength of contraction or
contractility.
-increases renin secretion from the kidneys
The Adrenergic receptor beta 2 is found... - ANSWER In all sympathetic target
organs except the heart
*inhibits smooth muscle
What do alpha and beta receptors do? - ANSWER A B C D (alpha causes
constriction, beta causes dilation)
