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Pharmacology HESI & NCLEX Review 2026 | Latest Questions, Answers & Exam Success Guide

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This document contains the latest Pharmacology HESI and NCLEX review questions with detailed answers and rationales to help students prepare effectively for nursing exams. It covers essential pharmacology concepts including drug classifications, side effects, nursing interventions, medication administration, and patient safety. The material is designed to support exam preparation for nursing students by focusing on commonly tested topics and high-yield pharmacology content. It is useful for both HESI practice and NCLEX review to strengthen understanding and improve exam performance.

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Institution
HESI Pharmacology
Course
HESI Pharmacology

Content preview

CCCCCCC
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCC




Pharmacology HESI & NCLEX Review C C C C




2026 | Latest Questions, Answers &
C C C C C C




Exam Success Guide C C C




THIS EXAM CONTAINS: C C




• Comprehensive Pharmacology review notes C C C




• HESI and NCLEX-style practice questions
C C C C




• Detailed answers C




• Dosage calculation practice C C




• NCLEX test-taking strategies C C




• Graded A+ CC

,Pharmacology HESI & NCLEX Review 2026 | Latest Questions, & Exam SuccessC C C C C C C C C C C




Guide
C




1. A male client who has been taking a high dose of a nonsteroidal anti-
C C C C C C C C C C C C C C




inflammatory drug (NSAID) comes to the clinic complaining of gastric pain and
C C C C C C C C C C C




blood in his stool. The healthcare provider discontinues the NSAIDs and prescribes
C C C C C C C C C C C C




esomeprazole. Which information should the client include in the nurse's teaching
C C C C C C C C C C C




plan?
C




A. Once pain subsides, NSAID therapy can be continued
C C C C C C C C




B. Resume a diet that consists of milk, cream, and bland foods
C C C C C C C C C C C




C. Notify the healthcare provider of the passage of black stool
C C C C C C C C C C




D. Call the clinic if diarrhea or headache occur when taking esomeprazole
C C C C C C C C C C C




Correct Answer: C C C




2. When administering zolpidem to an older client, which computer documentation
C C C C C C C C C C




indicates that the desired outcome has been achieved?
C C C C C C C C




A. Sleeps soundly through the night
C C C C C




B. Decreased episodes of incontinence
C C C C




C. Exhibits fewer emotional outburst
C C C C




D. Improved ability to concentrate
C C C C




Correct Answer: A C C




3. A male client with a fungal infection of the toenail reports to the nurse that he has
C C C C C C C C C C C C C C C C C




been applying an over-the-counter triple antibiotic ointment to the infection daily
C C C C C C C C C C C




for two weeks without any improvement. Which action should the nurse take?
C C C C C C C C C C C C




A. Instruct the client to obtain a prescription for oral terbinafine
C C C C C C C C C C




B. Suggest that the client use the ointment twice a day to be more effective
C C C C C C C C C C C C C C




C. Reassure that the treatment of fungus-infected toenails often takes several
C C C C C C C C C C




months
C




D. Advise the client to obtain a prescription-strength formulation of the ointment
C C C C C C C C C C C

,Correct Answer: A C C




4. A client with a nasogastric tube (NGT) has a prescription for sucralfate. The liquid
C C C C C C C C C C C C C C




form of the medication is not currently available in the pharmacy and tablets have
C C C C C C C C C C C C C C




been delivered to the medication dispensing system. Which action should the
C C C C C C C C C C C




nurse include when administering the medication?
C C C C C C




A. Crush the tablet and mix it with water separately from other medications
C C C C C C C C C C C C




B. Crush the tablet and mix it with other crushed tablets diluted in water
C C C C C C C C C C C C C




C. Withhold the medication until a liquid form is available on the nursing unit
C C C C C C C C C C C C C




D. Crush the tablet and mix it with other liquid medications for administration
C C C C C C C C C C C C




Correct Answer: A C C




Page 2 C




5. A client with chronic asthma receives a prescription for montelukast, a
C C C C C C C C C C C




leukotriene modifier. Which statement by the client indicates to the nurse that
C C C C C C C C C C C C




medication teaching was effective?
C C C C




A. "I should take this medication only when I am having an asthma attack"
C C C C C C C C C C C C C




B. "I will take the tablet every evening to control my asthma"
C C C C C C C C C C C




C. "This medication will stop an asthma attack immediately"
C C C C C C C C




D. "I will not need to use my inhalers twice a day when I start this medication"
C C C C C C C C C C C C C C C C




Correct Answer: B C C




6. The nurse is planning to administer the antiulcer GI agent sucralfate to a client
C C C C C C C C C C C C C C




with peptic ulcer disease. Which action should the nurse include in this client's plan
C C C C C C C C C C C C C C




of care?
C C




A. Assess for secondary Candida infection
C C C C C




B. Administer sucralfate once a day, preferably at bedtime
C C C C C C C C

, C. Give sucralfate on an empty stomach
C C C C C C




D. Monitor for electrolyte imbalance
C C C C




Correct Answer: C C C




7. A client with anemia secondary to chronic kidney disease (CKD) started a
C C C C C C C C C C C C




prescription for epoetin alfa two months ago. Which client finding best indicates
C C C C C C C C C C C C




that the medication is effective?
C C C C C




A. Reports of increased energy levels and decreased fatigue
C C C C C C C C




B. Takes concurrent iron therapy without adverse effects
C C C C C C C




C. Food diary shows increased consumption of iron-rich foods
C C C C C C C C




D. Hemoglobin level increased to 12 grams/dL (120 mmol/L)
C C C C C C C C




Correct Answer: D C C




8. The healthcare provider prescribes propylthiouracil (PTU) and Lugol's solution, a
C C C C C C C C C C




strong iodine solution, for a client with hyperthyroidism. How should the nurse
C C C C C C C C C C C C




schedule the administration of these medications?
C C C C C C




A. Administer iodine one hour before PTU
C C C C C C




B. Offer both drugs together with a meal
C C C C C C C




C. Schedule both medications at bedtime
C C C C C




D. Give parental dose once every 24 hours
C C C C C C C




Correct Answer: B C C




Page 3 C




9. Twenty minutes after the nurse starts a secondary IV infusion of cefepime 2
C C C C C C C C C C C C C




grams using an infusion pump to deliver the dose in one hour, the client reports
C C C C C C C C C C C C C C C




feeling nauseated. Which action should the nurse implement?
C C C C C C C C

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Institution
HESI Pharmacology
Course
HESI Pharmacology

Document information

Uploaded on
May 9, 2026
Number of pages
152
Written in
2025/2026
Type
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Contains
Questions & answers

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