NR 507 Edapt Week 5 Depression |
Questions and Answers | 2026 Update |
100% Accurate.
Q1. According to the monoamine deficiency theory, which three neurotransmitters
are primarily implicated in the pathophysiology of major depressive disorder?
A. Acetylcholine, GABA, and glutamate
B. Serotonin, norepinephrine, and dopamine
C. Epinephrine, histamine, and substance P
D. Endorphins, enkephalins, and dynorphins
,,answer,,,: B. Serotonin, norepinephrine, and dopamine
Q2. A patient reports depressed mood, anhedonia, significant weight loss,
insomnia, fatigue, feelings of worthlessness, and poor concentration for the past 3
weeks. How many DSM-5 criteria symptoms are present for major depressive
disorder?
A. 5
B. 6
C. 7
D. 8
,,answer,,,: C. 7 (depressed mood, anhedonia, weight loss, insomnia, fatigue,
worthlessness, poor concentration)
Q3. What is the minimum duration of symptoms required to diagnose a major
depressive episode?
,A. 1 week
B. 2 weeks
C. 4 weeks
D. 6 weeks
,,answer,,,: B. 2 weeks
Q4. Which two symptoms must be present (at least one of them) to meet criteria
for a major depressive episode?
A. Insomnia and fatigue
B. Depressed mood and anhedonia
C. Weight change and psychomotor changes
D. Guilt and suicidal ideation
,,answer,,,: B. Depressed mood and anhedonia (loss of interest or pleasure)
Q5. A patient with depression has low serotonin and norepinephrine levels. Which
class of medications directly increases both of these neurotransmitters?
A. SSRIs
B. SNRIs
C. MAOIs
D. TCAs
,,answer,,,: B. SNRIs (serotonin-norepinephrine reuptake inhibitors)
Q6. Which brain region shows decreased activity in patients with major depressive
disorder and is responsible for attention, memory, mood regulation, and
personality?
,A. Amygdala
B. Hippocampus
C. Prefrontal cortex
D. Hypothalamus
,,answer,,,: C. Prefrontal cortex
Q7. A patient has a depressive episode with extreme agitation, racing thoughts, and
hallucinations. This presentation is more suggestive of which condition?
A. Unipolar major depressive disorder
B. Bipolar depression
C. Dysthymia
D. Adjustment disorder
,,answer,,,: B. Bipolar depression (agitation and hallucinations during depression
point toward bipolar spectrum)
Q8. A patient experiences a distinct period of abnormally elevated mood lasting 8
days. They are spending recklessly, sleeping only 3 hours per night, and have
grandiose delusions. How is this episode classified?
A. Hypomanic episode
B. Manic episode
C. Mixed episode
D. Cyclothymic episode
,,answer,,,: B. Manic episode (duration >1 week, functional impairment, psychotic
features)
Q9. What is the minimum duration required for a hypomanic episode?
, A. 24 hours
B. 4 days
C. 1 week
D. 2 weeks
,,answer,,,: B. 4 consecutive days
Q10. A patient has had at least one manic episode. No major depressive episode is
required for diagnosis. Which disorder does this patient have?
A. Bipolar II disorder
B. Cyclothymic disorder
C. Bipolar I disorder
D. Major depressive disorder
,,answer,,,: C. Bipolar I disorder
Q11. A patient has had at least one hypomanic episode and at least one major
depressive episode, but never a full manic episode. Which diagnosis is correct?
A. Bipolar I disorder
B. Bipolar II disorder
C. Cyclothymic disorder
D. MDD with mixed features
,,answer,,,: B. Bipolar II disorder
Q12. Using the DIG FAST mnemonic for mania, what does the "I" stand for?
A. Irritability
B. Insomnia (decreased need for sleep)
Questions and Answers | 2026 Update |
100% Accurate.
Q1. According to the monoamine deficiency theory, which three neurotransmitters
are primarily implicated in the pathophysiology of major depressive disorder?
A. Acetylcholine, GABA, and glutamate
B. Serotonin, norepinephrine, and dopamine
C. Epinephrine, histamine, and substance P
D. Endorphins, enkephalins, and dynorphins
,,answer,,,: B. Serotonin, norepinephrine, and dopamine
Q2. A patient reports depressed mood, anhedonia, significant weight loss,
insomnia, fatigue, feelings of worthlessness, and poor concentration for the past 3
weeks. How many DSM-5 criteria symptoms are present for major depressive
disorder?
A. 5
B. 6
C. 7
D. 8
,,answer,,,: C. 7 (depressed mood, anhedonia, weight loss, insomnia, fatigue,
worthlessness, poor concentration)
Q3. What is the minimum duration of symptoms required to diagnose a major
depressive episode?
,A. 1 week
B. 2 weeks
C. 4 weeks
D. 6 weeks
,,answer,,,: B. 2 weeks
Q4. Which two symptoms must be present (at least one of them) to meet criteria
for a major depressive episode?
A. Insomnia and fatigue
B. Depressed mood and anhedonia
C. Weight change and psychomotor changes
D. Guilt and suicidal ideation
,,answer,,,: B. Depressed mood and anhedonia (loss of interest or pleasure)
Q5. A patient with depression has low serotonin and norepinephrine levels. Which
class of medications directly increases both of these neurotransmitters?
A. SSRIs
B. SNRIs
C. MAOIs
D. TCAs
,,answer,,,: B. SNRIs (serotonin-norepinephrine reuptake inhibitors)
Q6. Which brain region shows decreased activity in patients with major depressive
disorder and is responsible for attention, memory, mood regulation, and
personality?
,A. Amygdala
B. Hippocampus
C. Prefrontal cortex
D. Hypothalamus
,,answer,,,: C. Prefrontal cortex
Q7. A patient has a depressive episode with extreme agitation, racing thoughts, and
hallucinations. This presentation is more suggestive of which condition?
A. Unipolar major depressive disorder
B. Bipolar depression
C. Dysthymia
D. Adjustment disorder
,,answer,,,: B. Bipolar depression (agitation and hallucinations during depression
point toward bipolar spectrum)
Q8. A patient experiences a distinct period of abnormally elevated mood lasting 8
days. They are spending recklessly, sleeping only 3 hours per night, and have
grandiose delusions. How is this episode classified?
A. Hypomanic episode
B. Manic episode
C. Mixed episode
D. Cyclothymic episode
,,answer,,,: B. Manic episode (duration >1 week, functional impairment, psychotic
features)
Q9. What is the minimum duration required for a hypomanic episode?
, A. 24 hours
B. 4 days
C. 1 week
D. 2 weeks
,,answer,,,: B. 4 consecutive days
Q10. A patient has had at least one manic episode. No major depressive episode is
required for diagnosis. Which disorder does this patient have?
A. Bipolar II disorder
B. Cyclothymic disorder
C. Bipolar I disorder
D. Major depressive disorder
,,answer,,,: C. Bipolar I disorder
Q11. A patient has had at least one hypomanic episode and at least one major
depressive episode, but never a full manic episode. Which diagnosis is correct?
A. Bipolar I disorder
B. Bipolar II disorder
C. Cyclothymic disorder
D. MDD with mixed features
,,answer,,,: B. Bipolar II disorder
Q12. Using the DIG FAST mnemonic for mania, what does the "I" stand for?
A. Irritability
B. Insomnia (decreased need for sleep)
