CHEM 210 BIO-CHEMISTRY MODULE 1-8
FINAL EXAM
NEWEST QUESTIONS AND
CORRECT DETAILED ANSWERS
CHEM 210 – MODULE 1
EXAM
1. Amino acids with negatively charged side chains at pH 7:
A. Asp, Glu
B. Lys, Arg
C. Ser, Thr
D. Asn, Gln
Answer: A
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2. Which amino acid is most likely phosphorylated besides Ser?
A. Gln
B. Tyr
C. Leu
D. Val
Answer: B
3. The pI of a neutral amino acid is approximated by:
A. (pKa1 + pKa2)/2
B. (pKaR + pKa1)/2
C. pKa1 – pKa2
D. (pKa1 × pKa2) Answer: A
4. Glycine is unique because it:
A. Is acidic
B. Is chiral
C. Has no side chain R group
D. Has two amino groups
Answer: C
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5. Which amino acid is most soluble in water?
A. Isoleucine
B. Phenylalanine
C. Asparagine
D. Leucine Answer: C
Rationale: Asparagine is polar.
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6. Increasing ionic strength can:
A. Increase solubility of proteins indefinitely
B. Cause salting-out
C. Increase protein synthesis
D. Prevent denaturation
Answer: B
7. The peptide Ala-Gly-Lys at physiological pH has net charge:
A. –1
B. 0
C. +1
D. +2
Answer: C
Rationale: Lysine contributes +1; termini roughly cancel.
8. The pKa of the α-carboxyl group of amino acids is approximately:
A. 2
B. 6
C. 9