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CSMLS PRACTICE EXAM 1 – CERTIFIED MEDICAL LABORATORY TECHNOLOGIST QUESTIONS AND CORRECT VERIFIED ANSWERS

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Prepare for the Canadian Society for Medical Laboratory Science (CSMLS) certification exam with this comprehensive practice test (#1). Contains exam-style questions with correct verified answers covering all major CSMLS competency domains: clinical chemistry (arterial blood gases pH/pCO2/HCO3 interpretation, osmolality, electrolytes, calcium, ammonia, trace elements, headspace GC, therapeutic drug monitoring, acetaminophen), hematology (CBC priorities, RBC morphology, anemia classification, leukemia identification, platelet disorders, coagulation PT/APTT, factor deficiencies, DIC, von Willebrand, hemophilia, thrombocytopenia, schistocytes, reticulocytes, cold agglutinins, ringed sideroblasts, LAP score, RDW, absolute retic count), transfusion science (antibody identification, anti-M, anti-K, anti-Fya, anti-E, anti-IH, delayed hemolytic transfusion reactions, DAT, IAT, crossmatching, compatibility, RBC phenotyping controls), microbiology (Gram stain interpretation, Kirby-Bauer disk diffusion, QC zone sizes, anaerobic culture, C. botulinum, mycobacteria Lowenstein-Jensen, Neisseria, Haemophilus, Candida albicans, urine culture community-acquired UTI, swab transport media, specimen processing priority), immunology (complement deficiency CD55/CD59, flow cytometry CLL CD5 positive B cells, hypersensitivity), histology (H&E staining troubleshooting, Weigert's hematoxylin, microtomy, cryostat, paraffin sectioning, decalcification endpoint test, xylene substitute), phlebotomy (order of draw, winged infusion, mastectomy, IV site, capillary puncture, needlestick first aid, patient communication, eye contact, cultural differences), laboratory safety (WHMIS, biosafety cabinet BSC, PPE removal order, chemical spills acetone, xylene eye wash 15 minutes, fire safety, biohazard risk group 3, TDG), quality management (Westgard rules 13S 22S, standard deviation, precision vs accuracy, QC troubleshooting, internal/external quality assessment, method validation, corrective maintenance, root cause analysis, utilization review), molecular diagnostics (PCR real-time, capillary electrophoresis electrokinetic injection, mass spectrometry base peak M+1), and professional practice (ethics, confidentiality, privacy legislation PHI, conflict resolution, collaboration, reflective practice, stress management deep breathing, interprofessional teamwork). Essential for CSMLS MLT certification success.

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CSMLS PRACTICE EXAM 1 QUESTIONS
AND CORRECT

ANSWERS VERIFIED ANSWERS




Which of the following conditions correlates with the arterial blood gas results
below?

pH: 7.31

pO2: 70mmHg pCO2: 55mmHg

HCO3- : 28mmol/l



a) Uncompensated respiratory acidosis

b) Uncompensated metabolic acidosis

c) Compensated metabolic acidosis

d) Compensated respiratory acidosis - ✔✔✔ Correct Answer >

Uncompensated respiratory acidosis



Which of the following devices is used to input data into the LIS?

a) Software

b) Keyboard

Page 1 of 77

,c) Projector

d) Printer - ✔✔✔ Correct Answer > Keyboard



Which of the following actions should be taken first when a new co- worker
consistently fails to replenish analyzer reagents at the end of their shift?

a) request a continuous learning plan for the co- worker

b) file a complaint with the supervisor

c) request a scheduling change

d) discuss the concern with the coworker directly - ✔✔✔ Correct Answer >
Discuss the concern with the coworker directly



Which of the following actions should be taken first when the room temperature
rises from 22 to 28 degrees Celsius in the hematology department?

a) Stop analyzing manual ESR samples and store at 37 degrees C

b) Reject all ESR samples

c) Ship manual ESR to a different lab for analysis

d) Stop analyzing manual ESR samples and store at 4 degrees C

- ✔✔✔ Correct Answer > Stop analyzing manual ESR samples and store at 4
degrees C



Which of the following conditions correlates with the results given below?
HGB: 100g/L

PLT: 12x10^9/L
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,Smear: Polychromasia, increased schistocytes



a) Aplastic anemia

b) ITP

c) TTP

d) HIT - ✔✔✔ Correct Answer > TTP



Which of the following injection methods is utilized in deoxyribonucleic acid
capillary electrophoresis?

a) Electrokinetic

b) Fixed loop

c) Manual syringe

d) Thermal spray - ✔✔✔ Correct Answer > Electrokinetic



Which of the following situations would cause a Kirby Bauer size to be smaller
than expected?

a) Disk applied 10 minutes after inoculation

b) Agar thickness of 4 mm

c) Inoculum equivalent to 1 McFarland Standard

d) Plate incubated for 14 hours - ✔✔✔ Correct Answer > Inoculum
equivalent to 1 McFarland Standard




Page 3 of 77

, Which of the following disorders correlates with the results given below?

PT: 35 seconds APTT: 85 seconds



a) Liver cirrhosis

b) Hemophilia C

c) Hemophilia B

d) Anti- phospholipid syndrome - ✔✔✔ Correct Answer > Liver cirrhosis



Which one of the following CBC results has the highest priority?

a) WBC 80.5 x 10^12/L and PLT 25 x 10^9/L

b) WBC 2.2 x 10^9/L and HGB 90g/L

c) RBC 5.53 x 10^9/L and MCV 68fL

d) RBC 3.33 x 10^9/L and MCV 122fL - ✔✔✔ Correct Answer > WBC
80.5 x 10^12/L and PLT 25 x 10^9/L



Which of the following results can be reported as target NOT detected, given
the following real- time PCR results?

a) 2, 9, 10

b) 2, 3, 6, 9, 10

c) 3, 6, 7, 8

d) 3, 6 - ✔✔✔ Correct Answer > 2, 9, 10



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