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WGU D115 – ASSESSMENT: ADVANCED PATHOPHYSIOLOGY FOR THE ADVANCED PRACTICE NURSE OBJECTIVE EXAM QUESTIONS AND CORRECT ANSWERS

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Prepare for the WGU D115 Advanced Pathophysiology for the Advanced Practice Nurse objective exam with this comprehensive question bank. Contains actual exam questions and correct answers covering all key pathophysiology domains: cardiovascular (primary hypertension genetics, left ventricular hypertrophy, Takotsubo cardiomyopathy, Raynaud disease, ventricular septal defect, Kawasaki disease coronary artery stenosis, heart failure, ejection fraction), renal (nephrotic syndrome, vesicoureteral reflux grade III, prerenal acute kidney injury, renal gluconeogenesis and hypoglycemia in type 1 diabetes, hypothalamic tumor increasing water excretion, erythropoietin suppression in renal disease), respiratory (cystic fibrosis defective chloride secretion, COPD exacerbations and aging lung function, continuous capnography for CO2 retention, bronchial tumor with Klebsiella pneumonia, epiglottitis Haemophilus influenzae type B), hematology (pernicious anemia, Hodgkin lymphoma Reed-Sternberg cells, anemia of renal disease, platelet count for petechiae/ecchymosis, compensatory increased heart rate in anemia), gastrointestinal (hepatic encephalopathy ammonia, hepatitis B icteric phase jaundice, intestinal obstruction prerenal AKI, chronic gastritis vitamin B12 deficiency, GERD pathophysiology lower esophageal sphincter abnormalities), musculoskeletal (fragility fracture osteoporosis, Legg-Calvé-Perthes disease femoral head blood supply interruption, fibromyalgia treatment antidepressants and acupuncture), integumentary (aging skin decreased melanocytes, pressure injury unstageable with slough/eschar, burn injury rule of nines 28% TBSA, burn shock lactated Ringer fluid resuscitation), neurology (multiple sclerosis demyelination, cerebral concussion post-accident, diabetes insipidus hypernatremia hyperosmolarity, peripheral nervous system impairment demyelinating polyneuropathy), psychiatry (schizophrenia auditory hallucinations, PTSD arousal cluster reckless behavior violence, stress physiological effects decreased glucose uptake), genetics (Down syndrome recurrent infections, BRCA1 breast and ovarian cancer risk, hereditary angioedema C1 esterase inhibitor, cystic fibrosis transmission both genetic donor parents, retinoblastoma chromosome 13q14 mutation, Down syndrome aspiration from GERD), reproductive (pelvic inflammatory disease chlamydia, testicular torsion, paraphimosis uncircumcised, hyperprolactinemia and PCOS with amenorrhea decreased FSH estrogen altered TSH, hirsutism polycystic ovarian syndrome), pediatrics (ventricular septal defect infant, Kawasaki disease stage IV, vesicoureteral reflux grade III, Legg-Calvé-Perthes disease, choanal atresia newborn, retinoblastoma leukocoria, epiglottitis tripod position, SIRS in septic child), and shock (neurogenic shock T5 injury bradycardia hypotension). Essential for WGU D115 advanced practice nurse pathophysiology exam success.

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Page 1 of 26




WGU D115 - ASSESSMENT ADVANCED
PATHOPHYSIOLOGY FOR THE
ADVANCED PRACTICE NURSE |
OBJECTIVE EXAM
QUESTIONS AND CORRECT ANSWERS




A 34-year-old patient is diagnosed with primary hypertension, and an
advanced practice registered nurse (APRN) is reviewing the causes of
the problem with the patient.

What is a cause of this diagnosis? - ✔✔✔ Correct Answer > Genetics



An advanced practice registered nurse (APRN) is meeting with an older
adult with complicated hypertension and a strong family history of
cardiovascular disease. The patient is reluctant to consider medications

,Page 2 of 26




for blood pressure control and would like to know the anticipated effect
if the blood pressure remains moderately elevated.

What is the anticipated pathological outcome for this patient if this
condition continues? - ✔✔✔ Correct Answer > Hypertrophy of left ventricle



A 56-year-old patient presents to an emergency department with acute
chest pain on the day after the funeral of a spouse. Diagnostic results
reveal ST elevation and elevated troponins.

What is the probable diagnosis of these symptoms? - ✔✔✔ Correct
Answer > Takotsubo cardiomyopathy



A patient presents in the clinic with a chief complaint of numbness and
tingling in the hands and fingertips that is relieved by warmth. The
patient reports fingers turning blue and white and has no other medical
history.

Which condition is the patient describing? - ✔✔✔ Correct Answer >
Raynaud disease

, Page 3 of 26




A two-month-old infant presents to a rural healthcare clinic for a routine
well-child check. A medical assistant alerts an advanced practice
registered nurse (APRN) after assessing vital signs with a HR of 200
bmp, RR of 40 bmp, and dropping percentiles on the growth chart.

Upon entering the room, the APRN notes increased breathing effort,
nasal flaring, and suprasternal retractions when the infant's mother is
attempting to feed the infant a bottle. Upon further assessment, the
APRN notes a grade 4 holosystolic murmur and cool extremities.

What is the probable diagnosis? - ✔✔✔ Correct Answer > Ventricular septal
defect



A child presents to a clinic with a fever, conjunctivitis, and a strawberry
tongue. An advanced practice registered nurse (APRN) assesses the
patient, and stage IV Kawasaki disease is suspected.

What is the pathological mechanism of this disorder? - ✔✔✔ Correct
Answer > Intimal thickening and stenosis of coronary arteries



A patient presents with complaints of dark urine and generalized
malaise. An advanced practice registered nurse (APRN) notes the voided
urine is frothy.

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