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USAHS 5125 Clinical Neuroscience Midterm Study Guide 2025 | Neuroscience Concepts, Practice Questions, and Exam Review

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This Clinical Neuroscience (5125) study guide for USAHS covers essential neuroanatomy and neurophysiology concepts commonly assessed in midterm examinations. Topics include brain structures and functions, neural pathways, sensory and motor systems, clinical correlations, and neurological disorders relevant to clinical practice. The material includes practice-style questions with detailed explanations designed to reinforce understanding and support effective exam preparation. Ideal for students reviewing neuroscience foundations for healthcare-related programs.

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5125 USAHS Clinical Neuroscience
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5125 USAHS Clinical Neuroscience

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A5125 USAHS CLINICAL
NEUROSCIENCE MIDTERM EXAM
(2026) UPDATE VERIFIED
QUESTIONS AND ANSWERS |
WITH 100% CORRECT ANSWERS
GRADED A+ GUARANTEED
SUCCESS!! LATEST UPDATE
taxia - answer-Loss of full coordination of body movements; can be appendicular
(extremities) or truncal (postural); commonly due to cerebellar lesion; assessed with
TULIA.



Appendicular ataxia - answer-Ataxia affecting limb coordination; tested with finger-to-
nose, heel-to-shin, dysdiadochokinesia tests.



Truncal ataxia - answer-Ataxia affecting postural and core stability; patient has wide-
based gait and difficulty sitting or standing unsupported.



Ideational apraxia - answer-Incorrect tool use; impaired ability to sequence a multistep
task logically (e.g., brushing hair with toothbrush).



Ideomotor apraxia - answer-Knows the steps but cannot execute movement on
command; automatic movements may be intact.



Snellen chart - answer-Gold standard for testing visual acuity; primarily assesses CN II
(optic nerve).



CN II optic nerve function - answer-Sensory nerve responsible for vision, visual acuity,
and afferent limb of pupillary reflex.

,Right optic nerve lesion - answer-Causes right monocular blindness (loss of entire right
visual field), because lesion is before optic chiasm.



Basal Ganglia Go pathway - answer-Excitatory pathway facilitating voluntary movement;
dopamine (D1) increases activity.



Basal Ganglia No-Go pathway - answer-Inhibitory pathway suppressing unwanted
movement; dopamine (D2) modulates inhibition.



Basal Ganglia Hyper-direct pathway - answer-Rapid "stop" pathway that halts
movement mid-action via subthalamic nucleus.



Substantia nigra pars compacta - answer-BG nucleus releasing dopamine that
modulates Go and No-Go pathways; dopamine = excitatory effect; GABA = inhibitory
transmitter.



Cogwheel rigidity - answer-Ratcheting resistance during PROM; common in Parkinson's
disease due to rigidity + tremor overlap.



Global aphasia - answer-Severe deficit in both speech production and comprehension;
usually due to large left perisylvian lesion.



Broca's aphasia - answer-Non-fluent, effortful speech; comprehension intact; lesion in
left inferior frontal gyrus.



Wernicke's aphasia - answer-Fluent speech with incorrect words and impaired
comprehension; lesion in left superior temporal gyrus.



Vestibular lesion symptoms - answer-Vertigo, dizziness, nausea, ataxia, imbalance, and
nystagmus; may be peripheral (inner ear/nerve) or central (brainstem/cerebellum).

, Peripheral vestibular disorders - answer-BPPV (displaced otoconia), vestibular neuritis
(nerve inflammation), Ménière's disease (endolymphatic fluid disorder causing episodic
vertigo + hearing loss).



Peripheral vs Central vestibular signs - answer-Peripheral = more intense vertigo,
fatigable nystagmus, positive Dix-Hallpike; Central = non-fatigable nystagmus,
neurological signs, cerebellar involvement.



Trigeminal sensory screening - answer-Occlude vision; lightly touch forehead, cheek,
and jaw (V1, V2, V3) with cotton; client reports detection.



Trigeminal neuralgia - answer-Sudden, severe, electric-shock pain in one or more
trigeminal branches; often triggered by touch or chewing; usually unilateral.



Dizziness differential screening - answer-Assess Triggers, Timing, Oculomotor signs
(nystagmus, gaze), Provocative testing (Dix-Hallpike), and other neurological deficits to
differentiate central vs peripheral causes.



ALS (amyotrophic lateral sclerosis) - answer-Progressive degeneration of UMN + LMN
causing weakness, fasciculations, hyperreflexia, dysphagia, and eventual respiratory
failure.



Superior cerebellar peduncle function - answer-Major efferent output from cerebellum
to red nucleus and thalamus.



Middle cerebellar peduncle function - answer-Major afferent input from contralateral
pontine nuclei.



Inferior cerebellar peduncle function - answer-Carries both afferent (from vestibular +
spinal) and efferent fibers.

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5125 USAHS Clinical Neuroscience
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5125 USAHS Clinical Neuroscience

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