EXAM
Exam Solutionga
NR546 psychopharmacology Final exam 2026 A+ GRAD ga ga ga ga ga ga
E ASSURED COMPLETE SOLUTIONS AND VERIFIED ANS
ga ga ga ga ga ga
WERS (B9419) ga
QUESTION 1 ga
monoamine hypothesis of depression ga ga ga
ANSWER
depression occurs as a result of deficiency of 1 or all 3 monoamine NT -
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
occurs due to too little positive affect or too much negative affect (mania will occur from excess of all 3
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
)
QUESTION 2 ga
what are the three monoamine NT
ga ga ga ga ga
ANSWER
NE, DA, 5HT
ga ga
QUESTION 3 ga
too little positive affect
ga ga ga
ANSWER
-DA/NE dysfunction -DA levels low = loss of pleasure, interest, alertness, self-confidence -
ga ga ga ga ga ga ga ga ga ga ga ga
DA levels high = hallucinations seen in schizo -
ga ga ga ga ga ga ga ga
NE (fight or flight) high = antsy, nervous, affects focus ability -
ga ga ga ga ga ga ga ga ga ga ga
depressed mood, loss of joy, lack of interest, loss of energy, decreased alertness, decreased self-
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
confidence, appetite changes ga ga
QUESTION 4 ga
too much negative affect
ga ga ga
,ANSWER
-
5HT = relaxation, comfort, decreases stress, regulates libido, arousal, sleep, aggression, pain perception
ga ga ga ga ga ga ga ga ga ga ga ga ga
-5HT/NE dysfunction - ga ga
depressed mood, guilt, fear/anxiety, hostility, irritability, loneliness, appetite changes
ga ga ga ga ga ga ga ga
QUESTION 5 ga
prescribing considerations ga
ANSWER
-client preference -prior treatment response -anticipated adverse effects -comorbidities -half-
ga ga ga ga ga ga ga ga ga
life interactions -cost
ga ga
QUESTION 6 ga
client preferencega
ANSWER
if no contraindication, then prescribe that med to improve adherence
ga ga ga ga ga ga ga ga ga
QUESTION 7 ga
prior treatment response
ga ga
ANSWER
if patient had success with a previous med, prescribe that one first
ga ga ga ga ga ga ga ga ga ga ga
QUESTION 8 ga
anticipated adverse events ga ga
ANSWER
-consider age, family planning, and anticipated adverse effects. -
ga ga ga ga ga ga ga ga
use adverse effects to pt's advantage (choose a known activating medication for a pt with atypical depr
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
ession or choose a sedating medication for a patient with sleep disturbances)
ga ga ga ga ga ga ga ga ga ga ga
QUESTION 9 ga
Comorbidities
ANSWER
,clients with comorbid anxiety may experience worsening symptoms when taking medications that targe
ga ga ga ga ga ga ga ga ga ga ga ga
t NE (SNRIs) -
ga ga ga
fluoxetine is known to activate clients and cause panic attacks in clients with comorbid anxiety
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
QUESTION 10 ga
half-life interactions ga
ANSWER
-
choose a medication with a longer half life to avoid discontinuation syndrome if your client forgets to t
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
ake it - ga ga
many antidepressants have significant interactions with other meds due to CYP450 enzyme involvemen
ga ga ga ga ga ga ga ga ga ga ga ga
t
QUESTION 11 ga
cost
ANSWER
if client cant afford medication, they will not benefit. keep cost, insurance benefits, and pharmaceutical
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
assistance programs in mind ga ga ga
QUESTION 12 ga
goal of antidepressant medications
ga ga ga
ANSWER
complete remission of symptoms ga ga ga
QUESTION 13 ga
antidepressant prescribing schedule ga ga
ANSWER
-start on a single drug for 4-8 weeks -
ga ga ga ga ga ga ga ga
if not working: 1. increase dose gradually until efficacy occurs 2. switch to different drug within same d
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
rug class after adequate trial which included higher dosing and a minimum of 8 weeks 3. switch to a dr
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
ug in a different class after adequate trial and higher dosing 4. add a second med as adjunct
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
QUESTION 14 ga
SSRI MOA ga
, ANSWER
inhibit 5HT reuptake first line of treatment for depression
ga ga ga ga ga ga ga ga
QUESTION 15 ga
SSRI s/e ga
ANSWER
7 S's of SSRIs 1. Stomach 2. sexual dysfunction 3. serotonin syndrome 4. sleep difficulties 5. suicidal tho
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
ughts 6. stress 7. size (weight)
ga ga ga ga ga
QUESTION 16 ga
serotonin s/e ga
ANSWER
head, red, fed head = decreased anxiety, impulsivity, sex drive red = platelets and bleeding fed = gi moti
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
lity and nausea
ga ga
QUESTION 17 ga
SSRI pt education ga ga
ANSWER
most adverse affects will subside after 4-5 days once body adjusts to increased serotonin levels
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
QUESTION 18 ga
SSRI drugs ga
ANSWER
citalopram fluoxetine paroxetine sertraline fluvoxamine bupropion
ga ga ga ga ga
QUESTION 19 ga
citalopram
ANSWER
*has a mild antihistamine effect *causes QT prolongation citalopram = celexa, think of cel LEXUS (car) =
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
car - get an electrocardiogram if on this drug
ga ga ga ga ga ga ga ga ga
QUESTION 20 ga
Exam Solutionga
NR546 psychopharmacology Final exam 2026 A+ GRAD ga ga ga ga ga ga
E ASSURED COMPLETE SOLUTIONS AND VERIFIED ANS
ga ga ga ga ga ga
WERS (B9419) ga
QUESTION 1 ga
monoamine hypothesis of depression ga ga ga
ANSWER
depression occurs as a result of deficiency of 1 or all 3 monoamine NT -
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
occurs due to too little positive affect or too much negative affect (mania will occur from excess of all 3
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
)
QUESTION 2 ga
what are the three monoamine NT
ga ga ga ga ga
ANSWER
NE, DA, 5HT
ga ga
QUESTION 3 ga
too little positive affect
ga ga ga
ANSWER
-DA/NE dysfunction -DA levels low = loss of pleasure, interest, alertness, self-confidence -
ga ga ga ga ga ga ga ga ga ga ga ga
DA levels high = hallucinations seen in schizo -
ga ga ga ga ga ga ga ga
NE (fight or flight) high = antsy, nervous, affects focus ability -
ga ga ga ga ga ga ga ga ga ga ga
depressed mood, loss of joy, lack of interest, loss of energy, decreased alertness, decreased self-
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
confidence, appetite changes ga ga
QUESTION 4 ga
too much negative affect
ga ga ga
,ANSWER
-
5HT = relaxation, comfort, decreases stress, regulates libido, arousal, sleep, aggression, pain perception
ga ga ga ga ga ga ga ga ga ga ga ga ga
-5HT/NE dysfunction - ga ga
depressed mood, guilt, fear/anxiety, hostility, irritability, loneliness, appetite changes
ga ga ga ga ga ga ga ga
QUESTION 5 ga
prescribing considerations ga
ANSWER
-client preference -prior treatment response -anticipated adverse effects -comorbidities -half-
ga ga ga ga ga ga ga ga ga
life interactions -cost
ga ga
QUESTION 6 ga
client preferencega
ANSWER
if no contraindication, then prescribe that med to improve adherence
ga ga ga ga ga ga ga ga ga
QUESTION 7 ga
prior treatment response
ga ga
ANSWER
if patient had success with a previous med, prescribe that one first
ga ga ga ga ga ga ga ga ga ga ga
QUESTION 8 ga
anticipated adverse events ga ga
ANSWER
-consider age, family planning, and anticipated adverse effects. -
ga ga ga ga ga ga ga ga
use adverse effects to pt's advantage (choose a known activating medication for a pt with atypical depr
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
ession or choose a sedating medication for a patient with sleep disturbances)
ga ga ga ga ga ga ga ga ga ga ga
QUESTION 9 ga
Comorbidities
ANSWER
,clients with comorbid anxiety may experience worsening symptoms when taking medications that targe
ga ga ga ga ga ga ga ga ga ga ga ga
t NE (SNRIs) -
ga ga ga
fluoxetine is known to activate clients and cause panic attacks in clients with comorbid anxiety
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
QUESTION 10 ga
half-life interactions ga
ANSWER
-
choose a medication with a longer half life to avoid discontinuation syndrome if your client forgets to t
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
ake it - ga ga
many antidepressants have significant interactions with other meds due to CYP450 enzyme involvemen
ga ga ga ga ga ga ga ga ga ga ga ga
t
QUESTION 11 ga
cost
ANSWER
if client cant afford medication, they will not benefit. keep cost, insurance benefits, and pharmaceutical
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
assistance programs in mind ga ga ga
QUESTION 12 ga
goal of antidepressant medications
ga ga ga
ANSWER
complete remission of symptoms ga ga ga
QUESTION 13 ga
antidepressant prescribing schedule ga ga
ANSWER
-start on a single drug for 4-8 weeks -
ga ga ga ga ga ga ga ga
if not working: 1. increase dose gradually until efficacy occurs 2. switch to different drug within same d
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
rug class after adequate trial which included higher dosing and a minimum of 8 weeks 3. switch to a dr
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
ug in a different class after adequate trial and higher dosing 4. add a second med as adjunct
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
QUESTION 14 ga
SSRI MOA ga
, ANSWER
inhibit 5HT reuptake first line of treatment for depression
ga ga ga ga ga ga ga ga
QUESTION 15 ga
SSRI s/e ga
ANSWER
7 S's of SSRIs 1. Stomach 2. sexual dysfunction 3. serotonin syndrome 4. sleep difficulties 5. suicidal tho
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
ughts 6. stress 7. size (weight)
ga ga ga ga ga
QUESTION 16 ga
serotonin s/e ga
ANSWER
head, red, fed head = decreased anxiety, impulsivity, sex drive red = platelets and bleeding fed = gi moti
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
lity and nausea
ga ga
QUESTION 17 ga
SSRI pt education ga ga
ANSWER
most adverse affects will subside after 4-5 days once body adjusts to increased serotonin levels
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
QUESTION 18 ga
SSRI drugs ga
ANSWER
citalopram fluoxetine paroxetine sertraline fluvoxamine bupropion
ga ga ga ga ga
QUESTION 19 ga
citalopram
ANSWER
*has a mild antihistamine effect *causes QT prolongation citalopram = celexa, think of cel LEXUS (car) =
ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga ga
car - get an electrocardiogram if on this drug
ga ga ga ga ga ga ga ga ga
QUESTION 20 ga