🧠SHEET
SKIN PHARMACOLOGY CRAM
– TEST REVIEW
🧴 TOPICAL VEHICLES – MATCH TO LESION
Vehicle Best For
Ointment Dry, thick lesions
Cream Moist or weepy areas
Gel/Solution Hairy/scalp areas
Foam Large areas, scalp
💢 CORTICOSTEROIDS
Use: Eczema, psoriasis, dermatitis
MOA: ↓ cytokines, immune response (anti-inflammatory)
🛑
Potency Range: I (weakest) to VII (strongest)
NO fluorinated steroids on face/groin → skin atrophy
Low Hydrocortisone 1%, Desonide
Mid Triamcinolone 0.1%, Fluticasone
High Fluocinonide, Halcinonide
Very High Clobetasol, Halobetasol
😷 ACNE
Patho: ↑ sebum + comedones + P. acnes + inflammation
Drug Use Notes
Tretinoin Comedonal acne Photosensitive
Adapalene/Tazarotene Mild/mod acne Less irritating (3rd gen)
Benzoyl Peroxide Mild acne (no inflammation) Antibacterial, drying
Clindamycin/Erythro Moderate acne (topical abx) Best w/ BPO to prevent resistance
Doxycycline Moderate/severe acne PO option, sun-sensitive
Isotretinoin Severe/cystic acne Category X, iPledge required
SKIN PHARMACOLOGY CRAM
– TEST REVIEW
🧴 TOPICAL VEHICLES – MATCH TO LESION
Vehicle Best For
Ointment Dry, thick lesions
Cream Moist or weepy areas
Gel/Solution Hairy/scalp areas
Foam Large areas, scalp
💢 CORTICOSTEROIDS
Use: Eczema, psoriasis, dermatitis
MOA: ↓ cytokines, immune response (anti-inflammatory)
🛑
Potency Range: I (weakest) to VII (strongest)
NO fluorinated steroids on face/groin → skin atrophy
Low Hydrocortisone 1%, Desonide
Mid Triamcinolone 0.1%, Fluticasone
High Fluocinonide, Halcinonide
Very High Clobetasol, Halobetasol
😷 ACNE
Patho: ↑ sebum + comedones + P. acnes + inflammation
Drug Use Notes
Tretinoin Comedonal acne Photosensitive
Adapalene/Tazarotene Mild/mod acne Less irritating (3rd gen)
Benzoyl Peroxide Mild acne (no inflammation) Antibacterial, drying
Clindamycin/Erythro Moderate acne (topical abx) Best w/ BPO to prevent resistance
Doxycycline Moderate/severe acne PO option, sun-sensitive
Isotretinoin Severe/cystic acne Category X, iPledge required
