NSG 552 PSYCHOPHARMACOLOGY
WILKES EXAM 3 STUDY GUIDE FALL
2026 QUESTIONS & VERIFIED
CORRECT ANSWERS
First Line Treatments for alcohol use disorder (according to Study Guide & Dynamed) -
Correct Answer ✔✔ naltrexone and acamprosate
Second Line Treatments for alcohol use disorder (according to study guide but not
dynamed) - Correct Answer ✔✔ Disulfuram and Bupropion (not FDA approved for
ETOH but second line according to study guide)
Second Line Treatment for alcohol use disorder (according to Dynamed) - Correct
Answer ✔✔ Disulfuram
Other off label medications for alcohol use disorder according to Dynamed - Correct
Answer ✔✔ Topiramate, gabapentin, baclofen
Other off label medications for alcohol use disorder according to Stahl's - Correct
Answer ✔✔ Topiramate, ondansetron
MOA of Naltrexone - Correct Answer ✔✔ Opioid Receptor Antagonist
MOA of Acamprosate - Correct Answer ✔✔ - weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
MOA of Disulfuram - Correct Answer ✔✔ inhibits enzyme (aldehyde dehydrogenase) in
the liver
Bupropions role in alcohol use disorder - Correct Answer ✔✔ Can diminish cravings for
etoh, treat underlying anxiety/depression
Safety Risk associated with bupropion and etoh - Correct Answer ✔✔ bupropion
increases the risk of seizures in those going through etoh withdrawal
s/s ETOH intoxication - Correct Answer ✔✔ impaired fine motor control, impaired
judgement and coordination, ataxic gait, poor balance, lethargy, difficulty sitting upright,
difficulty with memory and sitting upright, N/V, coma in levels 300mg/dL and over with
respiratory depression and death possible
, S/S of etoh withdrawal - Correct Answer ✔✔ Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
Severe: seizures (12-48 hours post consumption), hallucinations, Delirium Tremens
Delirium Tremens - Correct Answer ✔✔ 48-96 hours after last etoh consumption
includes anxiety, anorexia, nausea/vomiting, psychomotor agitation
Scale used to measure etoh withdrawal - Correct Answer ✔✔ CIWA
CIWA assesses: - Correct Answer ✔✔ n/v, tremor, paroxysmall sweats, anxiety,
agitation, tactile disturbances, auditory disturbances, visual disturbances, headaches,
orientation
CIWA scoring - Correct Answer ✔✔ <10=mild
10-15=moderate
>15=severe
What medication is FDA approved for both opioid use disorder and alcohol use
disorder? - Correct Answer ✔✔ Naltrexone
What routes of administration exist for Naltrexone - Correct Answer ✔✔ PO, monthly
injection (Vivitrol), implant
What is the First Line medication in maintaining abstinence after alcohol detoxification?
- Correct Answer ✔✔ Acamprosate
What medication can safely be used to treat alcohol use disorder in patients who keep
drinking alcohol? - Correct Answer ✔✔ Acamprosate
What medication used to treat alcohol use disorder can be safely administered to
patients with hepatitis and/or liver disease - Correct Answer ✔✔ Acamprosate
What medication used to treat alcohol use disorder is contraindicated with severe renal
disease? - Correct Answer ✔✔ Acamprosate
Aversion symptoms with Disulfuram - Correct Answer ✔✔ flushing, N/V, HA, vertigo,
SOB, hypotension, palpitation
How long do you need to wait to administer antabuse? - Correct Answer ✔✔ Person
needs to be alcohol free for 12 hours
Important Education for patients taking Disulfuram - Correct Answer ✔✔ Do not use
anything that contains alcohol: mouthwash, aftershave, perfumes, vinegar, cough
medicine for up to two weeks after last dose of disulfuram
WILKES EXAM 3 STUDY GUIDE FALL
2026 QUESTIONS & VERIFIED
CORRECT ANSWERS
First Line Treatments for alcohol use disorder (according to Study Guide & Dynamed) -
Correct Answer ✔✔ naltrexone and acamprosate
Second Line Treatments for alcohol use disorder (according to study guide but not
dynamed) - Correct Answer ✔✔ Disulfuram and Bupropion (not FDA approved for
ETOH but second line according to study guide)
Second Line Treatment for alcohol use disorder (according to Dynamed) - Correct
Answer ✔✔ Disulfuram
Other off label medications for alcohol use disorder according to Dynamed - Correct
Answer ✔✔ Topiramate, gabapentin, baclofen
Other off label medications for alcohol use disorder according to Stahl's - Correct
Answer ✔✔ Topiramate, ondansetron
MOA of Naltrexone - Correct Answer ✔✔ Opioid Receptor Antagonist
MOA of Acamprosate - Correct Answer ✔✔ - weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
MOA of Disulfuram - Correct Answer ✔✔ inhibits enzyme (aldehyde dehydrogenase) in
the liver
Bupropions role in alcohol use disorder - Correct Answer ✔✔ Can diminish cravings for
etoh, treat underlying anxiety/depression
Safety Risk associated with bupropion and etoh - Correct Answer ✔✔ bupropion
increases the risk of seizures in those going through etoh withdrawal
s/s ETOH intoxication - Correct Answer ✔✔ impaired fine motor control, impaired
judgement and coordination, ataxic gait, poor balance, lethargy, difficulty sitting upright,
difficulty with memory and sitting upright, N/V, coma in levels 300mg/dL and over with
respiratory depression and death possible
, S/S of etoh withdrawal - Correct Answer ✔✔ Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
Severe: seizures (12-48 hours post consumption), hallucinations, Delirium Tremens
Delirium Tremens - Correct Answer ✔✔ 48-96 hours after last etoh consumption
includes anxiety, anorexia, nausea/vomiting, psychomotor agitation
Scale used to measure etoh withdrawal - Correct Answer ✔✔ CIWA
CIWA assesses: - Correct Answer ✔✔ n/v, tremor, paroxysmall sweats, anxiety,
agitation, tactile disturbances, auditory disturbances, visual disturbances, headaches,
orientation
CIWA scoring - Correct Answer ✔✔ <10=mild
10-15=moderate
>15=severe
What medication is FDA approved for both opioid use disorder and alcohol use
disorder? - Correct Answer ✔✔ Naltrexone
What routes of administration exist for Naltrexone - Correct Answer ✔✔ PO, monthly
injection (Vivitrol), implant
What is the First Line medication in maintaining abstinence after alcohol detoxification?
- Correct Answer ✔✔ Acamprosate
What medication can safely be used to treat alcohol use disorder in patients who keep
drinking alcohol? - Correct Answer ✔✔ Acamprosate
What medication used to treat alcohol use disorder can be safely administered to
patients with hepatitis and/or liver disease - Correct Answer ✔✔ Acamprosate
What medication used to treat alcohol use disorder is contraindicated with severe renal
disease? - Correct Answer ✔✔ Acamprosate
Aversion symptoms with Disulfuram - Correct Answer ✔✔ flushing, N/V, HA, vertigo,
SOB, hypotension, palpitation
How long do you need to wait to administer antabuse? - Correct Answer ✔✔ Person
needs to be alcohol free for 12 hours
Important Education for patients taking Disulfuram - Correct Answer ✔✔ Do not use
anything that contains alcohol: mouthwash, aftershave, perfumes, vinegar, cough
medicine for up to two weeks after last dose of disulfuram
