IPS2: PHARMACOLOGY: TEST 4 QUESTIONS WITH COMPLETE
SOLUTIONS
1) Which of the following β-blockers is not used for congestive heart failure?
A) Propranolol
B) Metoprolol
C) Bisoprolol
D) Carvedilol -- Correct Answer ✔✔ a. Propranolol
2) NYHA Functional Class of Heart Failure that involves positive symptoms with less
than ordinary exertion:
A) Class I
B) Class II
C) Class III
D) Class IV -- Correct Answer ✔✔ c. Class III
3) Major mechanisms of antiarrhythmics, except:
A) Sodium channel blockade
, B) Blockade of parasympathetic autonomic effects in the heart
C) Prolongation of the effective refractory period
D) Calcium channel blockade -- Correct Answer ✔✔ b. Blockade of
parasympathetic autonomic effects in the heart
4) Strong Na+ channel blockade is observed with which Class I antiarrhythmic?
A) Class IA
B) Class IB
C) Class IC
D) All of the choices -- Correct Answer ✔✔ c. Class IC
5) Which of the following beta blockers have been found to be most useful as
antiarrhythmic agent/s?
I. Esmolol
II. Metoprolol
III. Propranolol
A) I only
B) II only
C) I and III
D) II and III -- Correct Answer ✔✔ c. I and III
6) Which is the primary mechanism of action of the drug Amiodarone?
A) Prolongs the action potential with block of the sodium channels
B) Shortens the action potential with block of the sodium channels
C) Prolongs the action potential with block of the potassium channels
D) Shortens the action potential with block of the potassium channels
-- Correct Answer ✔✔ c. Prolongs the action potential with block
of the potassium channels
,7) Wolff-Chaikoff is an effect of what antiarrhythmic drug?
A) Amiodarone
B) Propafenone
C) Sotalol
D) Tocainide -- Correct Answer ✔✔ a. Amiodarone
8) Which of the following calcium channel blockers is most useful in arrhythmia
therapy?
A) Verapamil
B) Diltiazem
C) Nifedipine
D) Lidocaine -- Correct Answer ✔✔ a. Verapamil
9) What is the preferred drug for the management of chronic paroxysmal
supraventricular tachycardia?
A) Lidocaine
B) Verapamil
C) Magnesium sulfate
D) Adenosine -- Correct Answer ✔✔ b. Verapamil
10) Which mechanism of action is for pegvisomant?
A) Inhibits release of growth hormone, glucagon, insulin and gastrin
B) Inhibits growth hormone release by 45 times and insulin release by
two times more compared to somatostatin
C) Inhibits growth hormone receptor
D) Any of the above -- Correct Answer ✔✔ c. Inhibits growth
hormone receptor
, 11) A somatostatin analog:
A) Pegvisomant
B) Mecasermin
C) Octreotide
D) Somatotropin -- Correct Answer ✔✔ c. Octreotide
12) Treatment for acute SIADH:
A) IV infusion of hypertonic saline
B) Demeclocycline
C) Tolvaptan
D) Conivaptan -- Correct Answer ✔✔ a. IV infusion of hypertonic
saline
13) Thyroxine except:
A) Naturally-occurring thyroid hormone
B) Dextro isomer
C) Critical for the development of many tissues in the body
D) T4 -- Correct Answer ✔✔ b. Dextro isomer
14) The recommended daily intake of iodide is:
A) 120 mcg
B) 130 mcg
C) 140 mcg
D) 150 mcg -- Correct Answer ✔✔ d. 150 mcg
15) Antithyroid agents such as perchlorate, pertechnetate and thiocyanate are:
SOLUTIONS
1) Which of the following β-blockers is not used for congestive heart failure?
A) Propranolol
B) Metoprolol
C) Bisoprolol
D) Carvedilol -- Correct Answer ✔✔ a. Propranolol
2) NYHA Functional Class of Heart Failure that involves positive symptoms with less
than ordinary exertion:
A) Class I
B) Class II
C) Class III
D) Class IV -- Correct Answer ✔✔ c. Class III
3) Major mechanisms of antiarrhythmics, except:
A) Sodium channel blockade
, B) Blockade of parasympathetic autonomic effects in the heart
C) Prolongation of the effective refractory period
D) Calcium channel blockade -- Correct Answer ✔✔ b. Blockade of
parasympathetic autonomic effects in the heart
4) Strong Na+ channel blockade is observed with which Class I antiarrhythmic?
A) Class IA
B) Class IB
C) Class IC
D) All of the choices -- Correct Answer ✔✔ c. Class IC
5) Which of the following beta blockers have been found to be most useful as
antiarrhythmic agent/s?
I. Esmolol
II. Metoprolol
III. Propranolol
A) I only
B) II only
C) I and III
D) II and III -- Correct Answer ✔✔ c. I and III
6) Which is the primary mechanism of action of the drug Amiodarone?
A) Prolongs the action potential with block of the sodium channels
B) Shortens the action potential with block of the sodium channels
C) Prolongs the action potential with block of the potassium channels
D) Shortens the action potential with block of the potassium channels
-- Correct Answer ✔✔ c. Prolongs the action potential with block
of the potassium channels
,7) Wolff-Chaikoff is an effect of what antiarrhythmic drug?
A) Amiodarone
B) Propafenone
C) Sotalol
D) Tocainide -- Correct Answer ✔✔ a. Amiodarone
8) Which of the following calcium channel blockers is most useful in arrhythmia
therapy?
A) Verapamil
B) Diltiazem
C) Nifedipine
D) Lidocaine -- Correct Answer ✔✔ a. Verapamil
9) What is the preferred drug for the management of chronic paroxysmal
supraventricular tachycardia?
A) Lidocaine
B) Verapamil
C) Magnesium sulfate
D) Adenosine -- Correct Answer ✔✔ b. Verapamil
10) Which mechanism of action is for pegvisomant?
A) Inhibits release of growth hormone, glucagon, insulin and gastrin
B) Inhibits growth hormone release by 45 times and insulin release by
two times more compared to somatostatin
C) Inhibits growth hormone receptor
D) Any of the above -- Correct Answer ✔✔ c. Inhibits growth
hormone receptor
, 11) A somatostatin analog:
A) Pegvisomant
B) Mecasermin
C) Octreotide
D) Somatotropin -- Correct Answer ✔✔ c. Octreotide
12) Treatment for acute SIADH:
A) IV infusion of hypertonic saline
B) Demeclocycline
C) Tolvaptan
D) Conivaptan -- Correct Answer ✔✔ a. IV infusion of hypertonic
saline
13) Thyroxine except:
A) Naturally-occurring thyroid hormone
B) Dextro isomer
C) Critical for the development of many tissues in the body
D) T4 -- Correct Answer ✔✔ b. Dextro isomer
14) The recommended daily intake of iodide is:
A) 120 mcg
B) 130 mcg
C) 140 mcg
D) 150 mcg -- Correct Answer ✔✔ d. 150 mcg
15) Antithyroid agents such as perchlorate, pertechnetate and thiocyanate are:
