for Health Care Professionals.
Instructions: Read each question carefully and select the best answer or the required options.
Domain 1: The Null Hypothesis, p-values & Significance (8 Questions)
1. A clinical trial investigates whether a new antihypertensive drug lowers systolic blood
pressure (SBP) more effectively than a placebo. The control group (placebo) has a known
mean SBP of 140 mmHg. What is the correct formulation of the Null Hypothesis (
H
0
) for this study?
A. The mean SBP of the new drug group is not equal to 140 mmHg.
B. The mean SBP of the new drug group is lower than 140 mmHg.
C. The mean SBP of the new drug group is equal to 140 mmHg. [CORRECT]
D. The variance in SBP is different between the two groups.
2. Researchers are comparing the mean blood pressure of patients taking a new drug versus
those taking a placebo. Which statement best represents the null hypothesis regarding the
population means?
A.
μ
drug
<μ
placebo
, B.
μ
drug
=μ
placebo
C.
μ
drug
>μ
placebo
D.
μ
drug
=μ
placebo