tamu chem 238 final, CHEM 238 FINAL, Ochem 2 Lab
Final| Updated RATED A+ | NEW 2026
1. Reac on of ethyl magnesium bromide with water will generate?
a. ethanol
b. ethane
c. butane
d. ethyl magnesium hydroxide
e. a peroxide
b
2. Under condi ons of thermodynamic control, product distribu on is governed by:
a. the rela ve stabili es of the products
b. the rela ve energies of the transi on states leading to the products
c. the rate at which each product is formed
d. a and b
e. b and c
a
3. Which of the following statements is false for the reduc on of camphor?
a. A hydride is transferred from the borohydride ion to the carbonyl of camphor.
b. Isoborneol is the major product.
c. One mole of NaBH4 can reduce four moles of camphor.
d. The borohydride ion can approach the camphor more easily from the exo side.
e. If LiAlH4 is used instead of NaBH4, ethanol cannot be used as a solvent.
d
4. In an aqueous organic extrac on,
a. the less dense layer is on top
b. the more dense layer is on top
c. aqueous layer is always on top
,d. the phase with less sample dissolved is always on top
e. the organic layer is always on top
d
5. The dimeric structure of diphosphomevalonate decarboxylase involves:
a. Covalent amide linkages
b. Van der Waals interac ons of non-polar side chains
c. Interac ons of polar sidechains of amino acids
d. Hydrogen bonding of amide carbonyls with nearby amide N-H bonds
e. Covalent disulfide linkages
c
6. A good classifica on test (reac on which provides easy detec on of posi ve result) for a
carboxylic acid is
a. the Hinsberg test
b. treatment with 2,4-dinitrophenylhydrazine solu on
c. sodium fusion
d. the evolu on of carbon dioxide upon addi on of sodium bicarbonate
e. reac on with thionyl chloride
d
7. What will happen if you don't cool the diazonium chloride salt before addi on of phenol?
a. It will s ll produce same diazonium compound
b. It will be converted to a phenol
c. It will be converted to an amine
d. It will produce a different diazonium compound
e. It will react with unreacted amine present in solu on
b
8. Which statement best describes the first steps in the aldol condensa on?
a. a-hydrogen abstrac on followed by enolate forma on
b. nucleophilic a<ack by hydroxide on carbonyl carbon followed by hydride transfer
c. aldehyde hydrogen abstrac on followed by enolate forma on
,d. aldehyde hydrogen abstrac on followed by hydride transfer
e. a-hydrogen abstrac on leading to enolate forma on
e
9. Which combina on might give an ester that will not be vola le enough to have significant
odor?
a. benzyl alcohol and salicylic acid
b. methyl alcohol and formic acid
c. methyl alcohol and ace c acid
d. ace c acid and 2-methyl-1-propanol
e. formic acid and ethyl alcohol
a
11. The purpose of spo>ng a mixture of all possible products on the TLC plate is to:
a. iden fy which product was synthesized by comparing your product to the Rf values from
the mixture
b. demonstrate which products you should have had
c. iden fy the dinitra on product
d. iden fy any impuri es
e. for comparison of the crude product
a
12. Which of the following chemicals will not react with Grignard Reagent?
a. water
b. carbon dioxide
c. ethyl ester
d. diethyl ether
e. acetone
d
13. The hydrobromina on (Addi on of H-Br) of the following compound gives a major product
and a minor product. Predict the products and determine whether they are kine c or
thermodynamic product
at 0degree C
, major = kine c
minor = thermo
14. What happens when we irradiate a molecule with UV radia on?
a. The bonds in the molecule start vibra ng faster.
b. The molecule breaks apart into smaller molecules.
c. Electrons in the molecule get excited from pi to pi* orbitals.
d. The molecules are polarized and aligned parallel to the UV beam e. The nuclear spin of the
molecule is inverted.
c
15. All of the reac ons below, except one, involve net oxida on or reduc on of the organic
reactant. Which reac on is neither an oxida on (increase in # of bonds from carbon to
electronega ve elements or decrease in # of C-H bonds) nor a reduc on?
a. nitra on of benzene (benzene to nitrobenzene)
b. camphor to borneol/isoborneol
c. cyclohexanol to cyclohexanone
d. ester synthesis (benzoic acid to methyl benzoate)
e. Tollens' test (aldehyde + silver ammonia complex)
d
16. In the pep des and amino acids lab, which of the following tests was used to detect the
presence of an alcohol?
a. Tollens' test
b. Permanganate test
c. Ceric nitrate test
e. b and c are correct
d. a and b are correct
e
17. Which of the following carboxylic acid deriva ves possesses the greatest reac vity toward
nucleophilic acyl subs tu on?
a. carboxylic acid anhydride
b. ester
c. alkyl acid chloride
Final| Updated RATED A+ | NEW 2026
1. Reac on of ethyl magnesium bromide with water will generate?
a. ethanol
b. ethane
c. butane
d. ethyl magnesium hydroxide
e. a peroxide
b
2. Under condi ons of thermodynamic control, product distribu on is governed by:
a. the rela ve stabili es of the products
b. the rela ve energies of the transi on states leading to the products
c. the rate at which each product is formed
d. a and b
e. b and c
a
3. Which of the following statements is false for the reduc on of camphor?
a. A hydride is transferred from the borohydride ion to the carbonyl of camphor.
b. Isoborneol is the major product.
c. One mole of NaBH4 can reduce four moles of camphor.
d. The borohydride ion can approach the camphor more easily from the exo side.
e. If LiAlH4 is used instead of NaBH4, ethanol cannot be used as a solvent.
d
4. In an aqueous organic extrac on,
a. the less dense layer is on top
b. the more dense layer is on top
c. aqueous layer is always on top
,d. the phase with less sample dissolved is always on top
e. the organic layer is always on top
d
5. The dimeric structure of diphosphomevalonate decarboxylase involves:
a. Covalent amide linkages
b. Van der Waals interac ons of non-polar side chains
c. Interac ons of polar sidechains of amino acids
d. Hydrogen bonding of amide carbonyls with nearby amide N-H bonds
e. Covalent disulfide linkages
c
6. A good classifica on test (reac on which provides easy detec on of posi ve result) for a
carboxylic acid is
a. the Hinsberg test
b. treatment with 2,4-dinitrophenylhydrazine solu on
c. sodium fusion
d. the evolu on of carbon dioxide upon addi on of sodium bicarbonate
e. reac on with thionyl chloride
d
7. What will happen if you don't cool the diazonium chloride salt before addi on of phenol?
a. It will s ll produce same diazonium compound
b. It will be converted to a phenol
c. It will be converted to an amine
d. It will produce a different diazonium compound
e. It will react with unreacted amine present in solu on
b
8. Which statement best describes the first steps in the aldol condensa on?
a. a-hydrogen abstrac on followed by enolate forma on
b. nucleophilic a<ack by hydroxide on carbonyl carbon followed by hydride transfer
c. aldehyde hydrogen abstrac on followed by enolate forma on
,d. aldehyde hydrogen abstrac on followed by hydride transfer
e. a-hydrogen abstrac on leading to enolate forma on
e
9. Which combina on might give an ester that will not be vola le enough to have significant
odor?
a. benzyl alcohol and salicylic acid
b. methyl alcohol and formic acid
c. methyl alcohol and ace c acid
d. ace c acid and 2-methyl-1-propanol
e. formic acid and ethyl alcohol
a
11. The purpose of spo>ng a mixture of all possible products on the TLC plate is to:
a. iden fy which product was synthesized by comparing your product to the Rf values from
the mixture
b. demonstrate which products you should have had
c. iden fy the dinitra on product
d. iden fy any impuri es
e. for comparison of the crude product
a
12. Which of the following chemicals will not react with Grignard Reagent?
a. water
b. carbon dioxide
c. ethyl ester
d. diethyl ether
e. acetone
d
13. The hydrobromina on (Addi on of H-Br) of the following compound gives a major product
and a minor product. Predict the products and determine whether they are kine c or
thermodynamic product
at 0degree C
, major = kine c
minor = thermo
14. What happens when we irradiate a molecule with UV radia on?
a. The bonds in the molecule start vibra ng faster.
b. The molecule breaks apart into smaller molecules.
c. Electrons in the molecule get excited from pi to pi* orbitals.
d. The molecules are polarized and aligned parallel to the UV beam e. The nuclear spin of the
molecule is inverted.
c
15. All of the reac ons below, except one, involve net oxida on or reduc on of the organic
reactant. Which reac on is neither an oxida on (increase in # of bonds from carbon to
electronega ve elements or decrease in # of C-H bonds) nor a reduc on?
a. nitra on of benzene (benzene to nitrobenzene)
b. camphor to borneol/isoborneol
c. cyclohexanol to cyclohexanone
d. ester synthesis (benzoic acid to methyl benzoate)
e. Tollens' test (aldehyde + silver ammonia complex)
d
16. In the pep des and amino acids lab, which of the following tests was used to detect the
presence of an alcohol?
a. Tollens' test
b. Permanganate test
c. Ceric nitrate test
e. b and c are correct
d. a and b are correct
e
17. Which of the following carboxylic acid deriva ves possesses the greatest reac vity toward
nucleophilic acyl subs tu on?
a. carboxylic acid anhydride
b. ester
c. alkyl acid chloride
