TEST BANK For Psychopharmacology: Drugs, the Brain, and Behavior, 4th Edition By Meyer Nursing, Verified Chapters 1 - 20, Complete Newest Version

Psychopharmacology Drugs the Brain And Behavior 4TH
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,Psychopharmacology Drugs the Brain And Behavior 4TH Edition meyer Nursing u u u u u u u b1u u u



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to accompany b1




Psychopharmacology, 4thEdition b1 b1



Meyer • Quenzer b1 b1




Chapter 1: Principles of Pharmacology b1 b1 b1 b1




Multiple Choice b1




1. refer(s) to specific molecular changes that occur when a drug binds to a
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particular target site or receptor, while
b1 b1 are the resulting widespread alterations
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in function.
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a. Drug action; therapeutic effects
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b. Side effects; drug effects
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c. Therapeutic effects; side effects b1 b1 b1



d. Drug action; drug effects b1 b1 b1



Answer: d b1



Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is free to
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bind at specific target sites is referred to as
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a. the therapeutic dose.
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b. first-pass effects. b1



c. bioavailability.
d. ED50.
Answer: c b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target
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site or receptor are referred to as
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a. drug effects. b1



b. drug action. b1



c. side effects. b1



d. placebo effects. b1



Answer: b b1



Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning b1



b. Genetic variation b1



c. Drug competition b1



d. Expectation of outcome b1 b1



Answer: c b1



Textbook Reference: Pharmacology: The Science of Drug Action
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Page 1 of 247
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,Psychopharmacology Drugs the Brain And Behavior 4TH Edition meyer Nursing u u u u u u u b1u u u



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5. The administration of oxytocin has been proposed as a treatment for autism. b1 b1 b1 b1 b1 b1 b1 b1 b1 b1



a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administration b1 b1



b. Lipid solubility b1



c. Depot binding b1



d. Drug action b1



Answer: d b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken b1 b1 b1 b1 b1 b1



a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
b1 b1 is not complete. b1 b1 b1 b1 b1 b1 b1 b1 b1 b1



a. cerebrospinal fluid b1



b. blood–brain barrier b1



c. choroid plexus b1



d. phospholipid membrane b1



Answer: b b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
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to general circulation.
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c. drugs must first survive the acidic environment of the stomach.
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d. salivary enzymes in the mouth begin the process of metabolism.
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Answer: b b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. b1



b. choroid plexus. b1



c. area postrema.
b1



d. median eminence. b1




Page 2 of 247
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, Psychopharmacology Drugs the Brain And Behavior 4TH Edition meyer Nursing u u u u u u u b1u u u



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Answer: c b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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11. Drugs administered _ have the most rapid onset of action.
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a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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12. Ionization of a drug depends on the of the solution and the
b1 b1 b1 b1 b1 b1 b1 b1 b1 b1 ofthe
drug.
b1



a. pH; pKab1



b. pKa; pH b1



c. concentration; lipid solubility b1 b1



d. pH; concentration
b1



Answer: a b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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13. The absorption of a drug depends on all of the following except
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a. lipid solubility.
b1



b. ionization.
c. body temperature.b1



d. the concentration of the drug.
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Answer: c b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highly lipid-soluble b1



Answer: a b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
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a. psychoactive drugs. b1



b. illicit drugs. b1



c. teratogens.
d. placental drugs. b1



Answer: c b1



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugs
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a. bind to their target sites.
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