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,ATI PN Comprehensive Predictor Form A, B, and C 2026-2027 Updated – Detailed Exam
Review Guide
Structure of ATI PN Comprehensive Predictor Exams
Forms A, B, and C are similar in structure but contain different questions. Each exam typically
includes:
• Medical-Surgical Nursing
• Pharmacology
• Maternal-Newborn Nursing
• Pediatric Nursing
• Mental Health Nursing
• Leadership and Management
• Infection Control and Safety
• Nutrition
• Therapeutic Communication
• NGN Clinical Judgment Cases
Major Topics Frequently Tested
1. Pharmacology
Pharmacology is one of the highest-weighted sections. Students are expected to understand:
• Medication classifications
• Side effects
• Contraindications
• Nursing implications
• Safe dosage administration
, • Adverse reactions
•
Commonly Tested Drugs
• Insulin
• Digoxin
• Warfarin
• Heparin
• Antihypertensives
• Opioids
• Antibiotics
• Bronchodilator
Question
A nurse is caring for a client taking digoxin. Which finding should the nurse report immediately?
A. Heart rate 52/min
B. Blood pressure 130/80 mmHg
C. Respiratory rate 18/min
D. Temperature 37°C
Correct Answer: A
Rationale
Digoxin can cause bradycardia. A heart rate below 60/min may indicate toxicity and requires
holding the medication and notifying the provider.
1. Basic Principles of Pharmacology
1. Pharmacokinetics (What the body does to the drug)
This includes how a drug moves through the body:
• Absorption: how the drug enters the bloodstream
• Distribution: how it spreads through body tissues
, • Metabolism: how the liver breaks it down
• Excretion: how kidneys remove it from the body
2. Pharmacodynamics (What the drug does to the body)
This describes how a drug produces its effect.
• Therapeutic effect (desired outcome)
• Side effects (expected but unwanted effects)
• Toxic effects (harmful reactions)
2. Major Drug Classifications (High-Yield for Exams)
1. Cardiovascular Drugs
a) Antihypertensives
Used to treat high blood pressure.
Examples:
• Lisinopril
• Amlodipine
• Metoprolol
Nursing considerations:
• Check blood pressure before giving
• Watch for dizziness and hypotension
b) Digoxin
Used for heart failure and atrial fibrillation.
Important effects:
• Increases heart contraction strength
• Slows heart rate