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RN Exit HESI Exam V5 Latest Update 2026 | Exam Prep | High-Yield Review Guide

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Prepare confidently for your nursing exit exam with this RN Exit HESI Exam V5 – Latest Update 2026 study guide. This high-yield review resource is designed to help nursing students focus on the most important concepts and commonly tested topics across the RN Exit HESI. The guide provides concise, organized content covering major nursing subjects, including medical-surgical nursing, pharmacology, maternal-child health, pediatrics, psychiatric nursing, and critical care. Ideal for comprehensive study or last-minute review, this resource helps reinforce key concepts, improve retention, and build confidence before exam day. What’s Included Latest Update 2026 content High-yield RN Exit HESI review Coverage of major nursing exam topics Organized format for efficient revision Ideal for final exam preparation Ideal For Nursing students preparing for RN Exit HESI V5 Final comprehensive review Self-study and concept reinforcement Building confidence before the exam

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RN Exit HESI Exam V5 Latest Update 2026 | Exam Prep |
High-Yield Review Guide
1. What is the recommended nursing action for a patient experiencing
sleeplessness and anxiety related to financial stress?

Encourage him to exercise vigorously before bed

Advise him to avoid all discussions about finances

Suggest he take sleeping pills

Reinforce the reality of his financial situation

2. If the nurse needs to administer 240,000 units of Penicillin G procaine but the
medication bio is labeled 600,000 units/2 ml instead of 1,200,000 units/2 ml,
how many ml should the nurse administer?

0.8 ml

1 ml

1.6 ml

0.4 ml

3. Why is it critical for the nurse to position the client with their head flat and
feet elevated in this scenario?

This position is used to prepare the client for transport to the hospital.

This position is necessary for administering medication safely.

This position prevents the client from choking during a seizure.

This position helps improve blood flow to the brain and may
alleviate symptoms of hypotension.

,4. A patient with gout is experiencing frequent flare-ups. How should the nurse
advise the patient regarding the use of allopurinol?

The patient should only take allopurinol during flare-ups.

The patient should take allopurinol daily to prevent flare-ups.

The patient should take allopurinol only when experiencing severe
pain.

The patient should stop taking allopurinol if symptoms improve.

5. What is the purpose of administering erythromycin ophthalmic ointment to a
newborn?

To enhance vision development

To reduce eye inflammation

To treat conjunctivitis

To prevent gonococcal ophthalmia neonatorum

6. Describe why unequal bilateral hand grip strengths are critical indicators in
assessing a patient with a right hemisphere stroke.

Unequal bilateral hand grip strengths indicate only sensory loss.

Unequal bilateral hand grip strengths suggest normal neurological
function.

Unequal bilateral hand grip strengths indicate potential motor
function impairment and require immediate intervention.

Unequal bilateral hand grip strengths are irrelevant in stroke
assessment.

,7. Why is it important to position a one-month-old infant on their stomach while
they are awake?

It allows the infant to sleep more soundly.

It helps to prevent flat head syndrome by promoting different head
positions.

It encourages the infant to develop stronger neck muscles.

It reduces the risk of choking during feeding.

8. Why is massaging the fundus and administering an oxytocic agent prioritized
immediately after delivery?

To collect necessary blood samples for laboratory analysis.

To ensure the infant is bonding with the mother immediately.

To assess for potential lacerations that may require suturing.

To prevent postpartum hemorrhage by promoting uterine
contraction.

9. What is the total number of units of Penicillin G procaine prescribed for the
child?

2 ml

1,200,000 units

240,000 units

1 ml

10. The nurse is caring for a patient diagnosed with an eating disorder. Which
nursing intervention is most important regarding this patient's physiological
assessment?

, Ask the patient about the presence of hallucinations.

Only a psychological assessment is necessary.

Monitor vital signs and laboratory studies.

Monitor for lack of exercise.

11. Describe the sequence of care that should be taken for a 36-week gestation
newborn after placing them in an isolette.

The nurse should prioritize administering vitamin K before any other
care.

After placing the newborn in the isolette, the nurse should ensure
warmth and administer erythromycin ophthalmic ointment to
prevent eye infections.

The nurse should remove wet linens before placing the infant in the
isolette.

The nurse should first assess the infant's vital signs before any other
interventions.

12. Which assessment finding indicates a lack of oxygen in the tissues and
requires immediate nursing intervention?

Cornea are jaundiced

Face is flushed and diaphoretic

Oral mucosa is cyanotic

Eyelids are matted and crusted

13. What is the first action a nurse should take when observing coffee ground
material in nasogastric tube drainage after an exploratory laparotomy?

Verify correct placement of the nasogastric tube

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