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HESI Exit RN Exam V6 Comprehensive Final Review 2026 | High-Yield Study Guide

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Prepare effectively for your nursing exit exam with this HESI Exit RN Exam V6 Comprehensive Final Review – Latest Update 2026. This high-yield study guide is designed to help nursing students focus on the most important concepts and commonly tested topics across the HESI Exit RN exam. The guide provides concise and organized review content covering key nursing areas, including medical-surgical nursing, pharmacology, maternal-newborn care, pediatrics, psychiatric nursing, and critical care. Ideal for comprehensive review or last-minute preparation, this resource helps reinforce essential concepts, improve retention, and build confidence before exam day. What’s Included Latest Update 2026 content Comprehensive HESI Exit RN V6 review High-yield nursing concepts Coverage of major nursing subject areas Organized format for efficient revision Ideal For Nursing students preparing for HESI Exit RN V6 Final comprehensive review Self-study and concept reinforcement Building confidence before exam day

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HESI Exit RN Exam V6 Comprehensive Final Review
2026 | High-Yield Study Guide

1. What medication is indicated for a client with elevated serum ammonia levels
due to liver cirrhosis?

Loperamide

Furosemide

IV human albumin

Lactulose

2. The nurse is planning an educational session for new parents on ways to
prevent sudden infant death syndrome (SIDS). Which information is most
important to provide parents of newborns and infants?

Do not prop bottles for an infant during naps and bedtime

Keep a bulb syringe accessible for use for an infant

Position the infant in a supine position while sleeping

Remove pillows and soft toys from the crib at bedtime

3. Which of the following conditions is primarily treated with antihistamines?

Allergic rhinitis

Bronchitis

Otitis media

Myocarditis

4. What is a common emotional response to grief that the nurse should explain
to the parents?

, Bargaining
Acceptance

Anger

Denial


5. What medication should the nurse administer to a client experiencing a
severe asthma attack?

Albuterol

Lidocaine

Prednisone

Atropine

6. What is the immediate nursing action required when a telemetry monitor
indicates ventricular fibrillation?

Give a dose of amiodarone IV

Prepare for external pacing

Administer IV atropine

Defibrillate with one shock

7. If a nurse observes that the IV site is pink and the dressing is loose, but the
patient is showing signs of infection, what should the nurse prioritize in their
intervention?

Redress the abdominal incision and assess for signs of infection.

Apply soft bilateral wrist restraints to prevent movement.

Replace the IV site with a smaller gauge immediately.

Leave the lights on in the room to monitor the patient.

,8. A nurse is reviewing a patient's nutritional assessment and notices a BMI
below the normal range. What is the likely classification for this patient's BMI?

Normal weight

Overweight

Underweight

Obese

9. Why is it important for the nurse to inform the client that birth is imminent
during the second stage of labor?

It allows the nurse to delay the delivery process.

It helps the client understand the urgency of the situation and
prepares them for delivery.

It ensures the client is comfortable before the delivery.

It provides time for the coach to arrive.

10. A patient presents with symptoms of sneezing, nasal congestion, and itchy
eyes. Which nursing intervention would be most appropriate?

Advise the patient to avoid all medications.

Refer the patient for immediate surgery.

Administer antihistamines as prescribed.

Prescribe antibiotics for potential infection.

11. Describe the role of lactulose in managing elevated ammonia levels in
patients with liver cirrhosis.

Lactulose helps to reduce serum ammonia levels by promoting its
excretion through the intestines.
Lactulose increases the absorption of ammonia in the gut.

, Lactulose acts as a diuretic to remove excess fluid.

Lactulose provides essential nutrients to the liver.

12. If the client's condition does not improve after administering albuterol, what
should the nurse's next step be in managing the asthma attack?

Discharge the client with a prescription for a rescue inhaler.

Immediately intubate the client to secure the airway.

Increase the dose of albuterol and administer it more frequently.

Assess the client for further respiratory distress and consider
additional interventions such as systemic corticosteroids or oxygen
therapy.

13. A patient with known primary adrenocortical insufficiency comes to the
Emergency Department (E.D.) with hypotension, hyponatremia,
hyperkalemia, fever, and confusion. A diagnosis of Addisonian crisis is made.
The nurse would expect the E.D. physician to order which of the following to
be given intravenously?

diuretics

ACTH

blood

hydrocortisone

14. What should the nurse communicate to the client who is entering the
second stage of labor?

Empty the client's bladder using a straight catheter

Prepare the client for spinal anesthesia

Prepare the coach to accompany the client to delivery

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