Rasmussen Pharmacology Final 100 Updated
Questions and Answers (2026) | Latest Practice
Review with Detailed Explanations | Grade A+
1. The nurse is talking with a new mother about medications that can be safely resumed
now that she is no longer pregnant. All the following medications are contraindicated
during pregnancy, but which one may be ingested while breastfeeding without causing
known infant harm?
A) Lithium
B) Methotrexate
C) Ibuprofen
D) Nicotine -✓✓C) Ibuprofen
2. Which statement by a client indicates an understanding of self-care precautions when
taking warfarin?
A) "My warfarin dose may need to be readjusted when I take a course of antibiotics."
B) "I should expect pink urine due to metabolic bi-products of the dye used in this
medication."
C) "Herbal remedies are fine, but I shouldn't take aspirin without consulting my
provider."
D) "I should eat spinach to increase my iron count if my INR goes below two." -✓✓A)
"My warfarin dose may need to be readjusted when I take a course of antibiotics."
3. Male client tells the nurse he awakens once or twice each night to video and has
difficulty starting his stream of urine. He describes these symptoms as " annoying." The
client provider examines him and notes that the prostate is moderately enlarged. The
client is sexually active and tells the nurse that he doesn't want to take any medication
that will interfere with sexual function. THe nurse anticipates the provider will order
which of the following?
A) Silodosin
B) A transurethral prostatectomy
C) Finasteride
D) Doxazosin -✓✓D) Doxazosin
4.A 50-year-old postmenopausal cleint who has had a hysterectomy has moderate to
severe hot flashes and is discussing estrogen therapy with the nurse. What will the
nurse tell the client regarding the side effect of estrogen therapy?
A) An estrogen progesterone product will increase side effects
B) Transdermal preparations of estrogen therapy have reduced side effects.
C) Side effects of estrogen therapy are uncommon among women of her age.
D) An intravaginal preparation may be best. -✓✓B) Transdermal preparations of
estrogen therapy have reduced side effects.
,5. A Client has an infection caused by pseudomonas aeruginosa, and the prescriber
has ordered intravenous piperacillin and tobramycin. Why might the nurse question this
combination of antibiotics?
A) This combination causes tendon rupture.
B) Aminoglycosides are inactivated by penicillins.
C) Aminoglycosides alone are adequate against pseudomonas. There is no need to risk
penicillin allergy.
D) Aminoglycosides increase the risk of penicillin allergy. -✓✓B) Aminoglycosides are
inactivated by penicillins.
6. A client with bronchitis is taking trimethoprim/sulfamethoxazole 160/800 mg orally,
twice daily. Before administering the third dose, the nurse observes the client has a
widespread rash, a temperature and a heart rate of 100 beats/min. The client looks ill
and reports not feeling well. What is the nurse's response?
A) Request an order for intravenous trimethoprim/ sulfamethoxazole.
B) Initiate probiotics.
C) Withhold the treatment and notify the provider of the symptoms.
D) Administer the dose and request an order for an antipyretic medication. -✓✓C)
Withhold the treatment and notify the provider of the symptoms.
7. A client with cancer has been taking an opioid analgesic four times daily for chronic
pain and reports needing increased doses for pain. What will the nurse tell the client?
A- Over time, people can develop tolerance to opioids. We can discuss increasing your
dose with the provider.
B- Take your medication more often to help control the pain
C- You are addicted and should take a different medication. We can discuss this with
your provider.
D- The risk of respiratory depression increases over time -✓✓A- Over time, people can
develop tolerance to opioids. We can discuss increasing your dose with the provider.
8) A client who is suffering from an acute gout attack wants to know how colchicine
differs from probenecid and allopurinol in its actions. Which of these statements shows
the need for further teaching regarding purpose and use of medications?
A- Allopurinol prevents the synthesis of uric acid.
B- All of these medications should be taken concurrently during an acute attack, and
NSAIDS should be added for pain control.
C- Colchicine reduces inflammation caused by uric acid
D- Probenecid facilitates the elimination of uric acid in the nephrons -✓✓B) All of these
medications should be taken concurrently during an acute attack, and NSAIDS should
be added for pain control.
9. The nurse understands that a bronchodilator would be most therapeutic in which
situation?
A- Irregular respiration, snoring, and intermittent episodes of apnea
B- fine, scattered crackles heard bilaterally in the bases
C- course crackles in the right lower lobe
, D- Shallow breath sounds with wheezing sounds in the upper lobes -✓✓D- Shallow
breath sounds with wheezing sounds in the upper lobes
10. The parents of a child with asthma ask the nurse why their child cannot use oral
corticosteroids more often because they are so effective. What is the correct response
by the nurse?
A- Frequent use of this drug may lead to a decreased response.
B- Chronic steroid use can show growth
C- A hypersensitivity reaction to this drug may occur.
D- systemic steroids are more toxic in children -✓✓B- Chronic steroid use can show
growth
11. A client taking warfarin presents with bruises, dark tarry stools, and an international
normalized ratio (INR) of 4.3. What is the nurse's action?
A) Hold the warfarin and consult the provider regarding the next steps.
B) Give an ampule of vitamin K, then call the physician to report client status.
C) Explain to the client the nurse may ask the provider to order a test for leukemia.
D) Give the warfarin with a dark green salad and check the next stool for blood. -✓✓A)
Hold the warfarin and consult the provider regarding the next steps.
12. The nurse will caution a client taking immunosuppressant drugs to avoid which
dietary supplement?
A) Glucosamine
B) Feverfew
C) Echinacea
D) Black cohosh -✓✓C) Echinacea
13. A client will begin taking fexofenadine for hay fever. What education should be
included regarding the use of this second-generation antihistamine?
A) Citrus fruit juices can inactivate this class of medications.
B) Fexofenadine has cholinergic side effects. It causes excessive salivation.
C) Fexofenadine must be taken at bedtime.
D) Fexofenadine must be taken apart from food -✓✓A) Citrus fruit juices can inactivate
this class of medications.
14. A client is discharged from the hospital with a prescription for
trimethoprim/sulfamethoxazole. What must the nurse include in the discharge teaching?
A) Take folic acid supplements.
B) Eat foods that are high in potassium.
C) Take the medication with food.
D) Drink eight to ten glasses of water each day. -✓✓D) Drink eight to ten glasses of
water each day.
15. Naloxone is effective because of which action?
A) Preventing activation of opioid receptors through antagonist actions
B) Regulating the sensitivity of opioid receptors by neurochemical alterations
Questions and Answers (2026) | Latest Practice
Review with Detailed Explanations | Grade A+
1. The nurse is talking with a new mother about medications that can be safely resumed
now that she is no longer pregnant. All the following medications are contraindicated
during pregnancy, but which one may be ingested while breastfeeding without causing
known infant harm?
A) Lithium
B) Methotrexate
C) Ibuprofen
D) Nicotine -✓✓C) Ibuprofen
2. Which statement by a client indicates an understanding of self-care precautions when
taking warfarin?
A) "My warfarin dose may need to be readjusted when I take a course of antibiotics."
B) "I should expect pink urine due to metabolic bi-products of the dye used in this
medication."
C) "Herbal remedies are fine, but I shouldn't take aspirin without consulting my
provider."
D) "I should eat spinach to increase my iron count if my INR goes below two." -✓✓A)
"My warfarin dose may need to be readjusted when I take a course of antibiotics."
3. Male client tells the nurse he awakens once or twice each night to video and has
difficulty starting his stream of urine. He describes these symptoms as " annoying." The
client provider examines him and notes that the prostate is moderately enlarged. The
client is sexually active and tells the nurse that he doesn't want to take any medication
that will interfere with sexual function. THe nurse anticipates the provider will order
which of the following?
A) Silodosin
B) A transurethral prostatectomy
C) Finasteride
D) Doxazosin -✓✓D) Doxazosin
4.A 50-year-old postmenopausal cleint who has had a hysterectomy has moderate to
severe hot flashes and is discussing estrogen therapy with the nurse. What will the
nurse tell the client regarding the side effect of estrogen therapy?
A) An estrogen progesterone product will increase side effects
B) Transdermal preparations of estrogen therapy have reduced side effects.
C) Side effects of estrogen therapy are uncommon among women of her age.
D) An intravaginal preparation may be best. -✓✓B) Transdermal preparations of
estrogen therapy have reduced side effects.
,5. A Client has an infection caused by pseudomonas aeruginosa, and the prescriber
has ordered intravenous piperacillin and tobramycin. Why might the nurse question this
combination of antibiotics?
A) This combination causes tendon rupture.
B) Aminoglycosides are inactivated by penicillins.
C) Aminoglycosides alone are adequate against pseudomonas. There is no need to risk
penicillin allergy.
D) Aminoglycosides increase the risk of penicillin allergy. -✓✓B) Aminoglycosides are
inactivated by penicillins.
6. A client with bronchitis is taking trimethoprim/sulfamethoxazole 160/800 mg orally,
twice daily. Before administering the third dose, the nurse observes the client has a
widespread rash, a temperature and a heart rate of 100 beats/min. The client looks ill
and reports not feeling well. What is the nurse's response?
A) Request an order for intravenous trimethoprim/ sulfamethoxazole.
B) Initiate probiotics.
C) Withhold the treatment and notify the provider of the symptoms.
D) Administer the dose and request an order for an antipyretic medication. -✓✓C)
Withhold the treatment and notify the provider of the symptoms.
7. A client with cancer has been taking an opioid analgesic four times daily for chronic
pain and reports needing increased doses for pain. What will the nurse tell the client?
A- Over time, people can develop tolerance to opioids. We can discuss increasing your
dose with the provider.
B- Take your medication more often to help control the pain
C- You are addicted and should take a different medication. We can discuss this with
your provider.
D- The risk of respiratory depression increases over time -✓✓A- Over time, people can
develop tolerance to opioids. We can discuss increasing your dose with the provider.
8) A client who is suffering from an acute gout attack wants to know how colchicine
differs from probenecid and allopurinol in its actions. Which of these statements shows
the need for further teaching regarding purpose and use of medications?
A- Allopurinol prevents the synthesis of uric acid.
B- All of these medications should be taken concurrently during an acute attack, and
NSAIDS should be added for pain control.
C- Colchicine reduces inflammation caused by uric acid
D- Probenecid facilitates the elimination of uric acid in the nephrons -✓✓B) All of these
medications should be taken concurrently during an acute attack, and NSAIDS should
be added for pain control.
9. The nurse understands that a bronchodilator would be most therapeutic in which
situation?
A- Irregular respiration, snoring, and intermittent episodes of apnea
B- fine, scattered crackles heard bilaterally in the bases
C- course crackles in the right lower lobe
, D- Shallow breath sounds with wheezing sounds in the upper lobes -✓✓D- Shallow
breath sounds with wheezing sounds in the upper lobes
10. The parents of a child with asthma ask the nurse why their child cannot use oral
corticosteroids more often because they are so effective. What is the correct response
by the nurse?
A- Frequent use of this drug may lead to a decreased response.
B- Chronic steroid use can show growth
C- A hypersensitivity reaction to this drug may occur.
D- systemic steroids are more toxic in children -✓✓B- Chronic steroid use can show
growth
11. A client taking warfarin presents with bruises, dark tarry stools, and an international
normalized ratio (INR) of 4.3. What is the nurse's action?
A) Hold the warfarin and consult the provider regarding the next steps.
B) Give an ampule of vitamin K, then call the physician to report client status.
C) Explain to the client the nurse may ask the provider to order a test for leukemia.
D) Give the warfarin with a dark green salad and check the next stool for blood. -✓✓A)
Hold the warfarin and consult the provider regarding the next steps.
12. The nurse will caution a client taking immunosuppressant drugs to avoid which
dietary supplement?
A) Glucosamine
B) Feverfew
C) Echinacea
D) Black cohosh -✓✓C) Echinacea
13. A client will begin taking fexofenadine for hay fever. What education should be
included regarding the use of this second-generation antihistamine?
A) Citrus fruit juices can inactivate this class of medications.
B) Fexofenadine has cholinergic side effects. It causes excessive salivation.
C) Fexofenadine must be taken at bedtime.
D) Fexofenadine must be taken apart from food -✓✓A) Citrus fruit juices can inactivate
this class of medications.
14. A client is discharged from the hospital with a prescription for
trimethoprim/sulfamethoxazole. What must the nurse include in the discharge teaching?
A) Take folic acid supplements.
B) Eat foods that are high in potassium.
C) Take the medication with food.
D) Drink eight to ten glasses of water each day. -✓✓D) Drink eight to ten glasses of
water each day.
15. Naloxone is effective because of which action?
A) Preventing activation of opioid receptors through antagonist actions
B) Regulating the sensitivity of opioid receptors by neurochemical alterations
