AND CORRECT ANSWERS GUARANTEED
TO PASS
●● Narcan
Answer: Treatment of choice for opiate overdose
It is prescribed routinely for all patients with opiate use disorder
Very short half-life
●● Methadone
Answer: Long acting full opioid receptor agonist at mu receptor
Restricted use to abuse trx facilities
Monitor for QTC prolongation(cardiac abnormalities
●● Suboxone
Answer: Opiod agonist/ antagonist
Decreased cravings
Can precipitate withdrawals if used too soon after full opioid agonist-it
will displace any residual opioids from the mu receptors
Sublingual preparation that is safer
Waiver needed to prescribe outpatient
Useful for patients with opiate use disorder with comorbid pain
,Suboxone can be used in pain management
●● Naltrexone
Answer: competitive opiod antagonist
Precipitate withdrawal if used within 7 days of heroine use
Available orally or monthly depot injections
Treatment of choice for highly motivated patients
Risk for LFT elevation
●● Opoid(Heroin)
Answer: Intoxication: miosis, hypotension, bradycardia, Low RR,
unconscious
Trx: Naloxone
Withdrawal: Anxiety, lacrimation, muscle aches, abdominal cramps and
diarrhea, seizures
Mgt: Buprenorphine/naloxone, clonidine, Bentyl
It is more effective at suppressing and controlling withdrawal than
methadone
●● Cocaine
Answer: Intoxication: Auditiory hallucinations, agitation, violent
behavior, muscle twitching, HTN, Tachycardia
Txt: Lorazepam
, Withdrawal: Antabuse use in cocaine use d/o= increases dopamine in the
brain reward circuit and act as an agonist trx in the setting of cocaine use
d/o
●● Cocaine induced chest pain and MI
Answer: Txt: Nitoglycerin, Aspirin
No Metoprolol
Beta blockers are contraindicated in patients with cocaine induced chest
pain-lowers coronary blood flow thereby worsening ischemia
●● Alcohol intoxication
Answer: Impaired fine motor control
Impaired judgment and coordination
Ataxic gait and poor balance
Lethargic, difficulty sitting upright, difficulty with memory
Nausea/Vomiting
Coma=Levels 300mg/dl and over
Respiratory depression and death possible
●● Alchohol withdrawal
Answer: Mild: Insomnia, irritability, Hand tremor
Moderate: Autonomic hyperactivity(diaphoresis, tachy, HTN), HTN