COMPLETE QUESTIONS WITH ACCURATE
ANSWERS
●● Naltrexone can be used for
Answer: both ETOH and opioid use disorders
●● What does naltrexone do
Answer: Reduces desire/cravings, First line treatment, Will precipitate
withdrawal in patients with physical opioid dependence
●● First line treatment in maintaining abstinence after detox
Answer: acamprosate
●● acamprosate can be used
Answer: in liver disease- not metabolized by the liver (not impacted by
ETOH use). Can be administered to patients with hepatitis, liver disease,
and those who continue drinking alcohol
●● acamprosate Contraindicated in
Answer: severe renal disease
,●● acamprosate helps with
Answer: Decreasing cravings
●● ETOH 2nd line treatment
Answer: disulfiram (Antabuse)
●● disulfiram (Antabuse) causes
Answer: aversion reaction to ETOH (flushing, headaches, n/v,
palpitation, SOB, vertigo, hypotension)
●● disulfiram (Antabuse) Do not
Answer: administer until the person has been alcohol free at least 12
hours
●● disulfiram (Antabuse) MOA
Answer: Blocks enzyme (aldehyde dehydrogenase) in the liver
●● ETOH withdrawal- Benzos
Answer: To keep patient calm and lightly sedated
●● Benzos MOA
Answer: Enhance the effects of GABA
, ●● Meds used in mild alcohol withdrawal
Answer: Tegretol, Valproic or Gabapentin
●● ETHO meds for nutritional deficiencies
Answer: Thiamine, folic acid, and multivitamin - 'Banana bag'
●● Wernicke's encephalopathy treatment
Answer: Parenteral Thiamine and Folate
●● Wernicke's encephalopathy cause
Answer: B1 deficiency
●● Cocaine mechanism
Answer: reuptake of dopamine, epinephrine, and NE = Stimulant effect
●● Cocaine effects on the body
Answer: has vasoconstrictive effects = can cause MI, stroke
●● Cocaine treatment options
Answer: NO FDA approved med; Off-label = naltrexone, modafinil,
Topamax