NSG533 EXAMINATION TEST 2026 FULL
QUESTIONS AND CORRECT SOLUTIONS
LEARNING GUIDE
◉ genome.
Answer: total genetic composition of an organism or species (group)
◉ genomics.
Answer: molecular analysis of the entire genome of a species
◉ gene.
Answer: basic unit of heredity
◉ list the four types of mendelian inheritance.
Answer: 1. autosomal dominant
2. autosomal recessive
3. X-linked dominant
4. X-linked recessive
◉ autosomal dominant.
,Answer: - phenotype is expressed in those who have 1 copy of a gene
mutation
- mothers and fathers are equally likely to transmit or inherit the
disorder
- seen in multiple generations
◉ autosomal recessive.
Answer: - requires presence of 2 copies of a gene mutation in order
to express phenotype
- usually seen in a single generation
- mothers/fathers equally likely to transmit or inherit disorder
◉ X-linked dominant.
Answer: - dominant disorder caused by a mutation in a gene on the
X chromosome
- heterozygous female (XAXa) and hemizygous male (XAY)
- affected males have more severe phenotype
,◉ X-Linked Recessive.
Answer: mutation on gene in X chromosome causes phenotype to be
expressed in hemizygous males (XaY) and homozygous females
(XaXa)
◉ types of X-linked recessive disorders.
Answer: 1. duchene muscular dystrophy
2. hemophilia
3. color blindness
◉ examples of X-Linked dominant disorders.
Answer: 1. Fragile X syndrome
2. Rett syndrome
◉ examples of Autosomal Dominant disorders.
Answer: -Marfan syndrome
-Huntington disease
◉ examples of Autosomal Recessive disorders.
Answer: - cystic fibrosis
- sickle cell anemia
, - PKU
- Tay-Sachs
◉ types of genetic inheritance.
Answer: 1. mendelian inheritance
2. non-mendelian inheritance
◉ types of non-mendelian inheritance.
Answer: 1. mitochondrial inheritance
2. genomic imprinting
3. uniparental disomy
◉ mitochondrial inheritance.
Answer: only females will transmit disease to their offspring
- the ova contains mitochondria, sperm does not
◉ genomic imprinting.
Answer: - gene from mother or father may be imprinted (silenced)
- if allele from mother is imprinted, only allele from father will be
expressed
QUESTIONS AND CORRECT SOLUTIONS
LEARNING GUIDE
◉ genome.
Answer: total genetic composition of an organism or species (group)
◉ genomics.
Answer: molecular analysis of the entire genome of a species
◉ gene.
Answer: basic unit of heredity
◉ list the four types of mendelian inheritance.
Answer: 1. autosomal dominant
2. autosomal recessive
3. X-linked dominant
4. X-linked recessive
◉ autosomal dominant.
,Answer: - phenotype is expressed in those who have 1 copy of a gene
mutation
- mothers and fathers are equally likely to transmit or inherit the
disorder
- seen in multiple generations
◉ autosomal recessive.
Answer: - requires presence of 2 copies of a gene mutation in order
to express phenotype
- usually seen in a single generation
- mothers/fathers equally likely to transmit or inherit disorder
◉ X-linked dominant.
Answer: - dominant disorder caused by a mutation in a gene on the
X chromosome
- heterozygous female (XAXa) and hemizygous male (XAY)
- affected males have more severe phenotype
,◉ X-Linked Recessive.
Answer: mutation on gene in X chromosome causes phenotype to be
expressed in hemizygous males (XaY) and homozygous females
(XaXa)
◉ types of X-linked recessive disorders.
Answer: 1. duchene muscular dystrophy
2. hemophilia
3. color blindness
◉ examples of X-Linked dominant disorders.
Answer: 1. Fragile X syndrome
2. Rett syndrome
◉ examples of Autosomal Dominant disorders.
Answer: -Marfan syndrome
-Huntington disease
◉ examples of Autosomal Recessive disorders.
Answer: - cystic fibrosis
- sickle cell anemia
, - PKU
- Tay-Sachs
◉ types of genetic inheritance.
Answer: 1. mendelian inheritance
2. non-mendelian inheritance
◉ types of non-mendelian inheritance.
Answer: 1. mitochondrial inheritance
2. genomic imprinting
3. uniparental disomy
◉ mitochondrial inheritance.
Answer: only females will transmit disease to their offspring
- the ova contains mitochondria, sperm does not
◉ genomic imprinting.
Answer: - gene from mother or father may be imprinted (silenced)
- if allele from mother is imprinted, only allele from father will be
expressed
