NSG6005 WEEK 1 EXAM 2026 SOUTH
UNIVERSITY STUDY GUIDE
COMPREHENSIVE QUESTIONS
ANSWERS VERIFIED A+
◉ Drugs that have a significant first pass effect:
o Must be given by enteral (oral) route only
o Bypass the hepatic circulation
o Are rapidly metabolized by the liver and may have little if any desired
action
o Are converted by the liver to more active in fat-soluble forms.
Answer: o Are rapidly metabolized by the liver and may have little if
any desired action
◉ When obtaining a drug history from Harold, he gives you a complete
list of his prescription medications. He denies taking any other drugs,
but you find that he occasionally takes aspirin for his arthritis flare-ups.
This is an example of:
o His appropriately only telling you about his regularly prescribed
medications
o His hiding information regarding his inappropriate use of aspirin from
you
o His common misconception that intermittently taking OTC
medications are not an important part of his drug history
,o A common misuse of OTC aspirin.
Answer: o His common misconception that intermittently taking OTC
medications are not an important part of his drug history
◉ Drugs that use CYP3A4 isoenzymes for metabolism may:
o Induce the metabolism of another drug
o Inhibit the metabolism of another drug
o Both A and B
o Neither A nor B.
Answer: o Both A and B
◉ A twenty four year old male received multiple fractures in a motor
vehicle accident that required significant amounts of opioid medication
to treat his pain. He is at risk for Type ____ ADR when he no longer
requires the opioids.
oA
oC
oE
o G.
Answer: o E
◉ Infants and young children are at higher risk of ADRs due to:
,o Immature renal function in schoolage children
o Lack of safety and efficacy studies in the pediatric population
o Children's skin being thicker than adults, requiring higher dosages of
topical medication
o Infant boys having a higher proportion of muscle mass, leading to a
higher volume of distribution.
Answer: o Lack of safety and efficacy studies in the pediatric population
◉ The type of ADR that is the result of an unwanted but otherwise
normal pharmacological action of a drug given in the usual therapeutic
dose is:
o Type A
o Type B
o Type C
o Type D.
Answer: o Type A
◉ A nurse practitioner would prescribe the liquid form of ibuprofen for
a six-year-old because:
o Drugs given in liquid form are less irritating to the stomach.
o A six-year-old may have problems swallowing a pill.
o Liquid forms of medication eliminate the concern for first-pass effect.
, o Liquid ibuprofen does not have to be dosed as often as tablet form..
Answer: o A six-year-old may have problems swallowing a pill.
◉ The role of the nurse practitioner in the use of herbal medication is to:
o Maintain competence in the prescribing of common herbal remedies.
o Recommend common OTC herbs to patients.
o Educate patients and guide them to appropriate sources of care.
o Encourage patients to not use herbal therapy due to the documented
dangers..
Answer: o Educate patients and guide them to appropriate sources of
care.
◉ Genetic polymorphisms account for differences in metabolism,
including:
o Poor metabolizers (PMs) that lack a working enzyme
o Intermediate metabolizers (IMs) that have one working, wild-type
allele and one mutant allele
o Extensive metabolizers (EMs), with two normally functioning alleles
o All of the above.
Answer: o All of the above
◉ The elderly are at high risk of ADRs due to:
UNIVERSITY STUDY GUIDE
COMPREHENSIVE QUESTIONS
ANSWERS VERIFIED A+
◉ Drugs that have a significant first pass effect:
o Must be given by enteral (oral) route only
o Bypass the hepatic circulation
o Are rapidly metabolized by the liver and may have little if any desired
action
o Are converted by the liver to more active in fat-soluble forms.
Answer: o Are rapidly metabolized by the liver and may have little if
any desired action
◉ When obtaining a drug history from Harold, he gives you a complete
list of his prescription medications. He denies taking any other drugs,
but you find that he occasionally takes aspirin for his arthritis flare-ups.
This is an example of:
o His appropriately only telling you about his regularly prescribed
medications
o His hiding information regarding his inappropriate use of aspirin from
you
o His common misconception that intermittently taking OTC
medications are not an important part of his drug history
,o A common misuse of OTC aspirin.
Answer: o His common misconception that intermittently taking OTC
medications are not an important part of his drug history
◉ Drugs that use CYP3A4 isoenzymes for metabolism may:
o Induce the metabolism of another drug
o Inhibit the metabolism of another drug
o Both A and B
o Neither A nor B.
Answer: o Both A and B
◉ A twenty four year old male received multiple fractures in a motor
vehicle accident that required significant amounts of opioid medication
to treat his pain. He is at risk for Type ____ ADR when he no longer
requires the opioids.
oA
oC
oE
o G.
Answer: o E
◉ Infants and young children are at higher risk of ADRs due to:
,o Immature renal function in schoolage children
o Lack of safety and efficacy studies in the pediatric population
o Children's skin being thicker than adults, requiring higher dosages of
topical medication
o Infant boys having a higher proportion of muscle mass, leading to a
higher volume of distribution.
Answer: o Lack of safety and efficacy studies in the pediatric population
◉ The type of ADR that is the result of an unwanted but otherwise
normal pharmacological action of a drug given in the usual therapeutic
dose is:
o Type A
o Type B
o Type C
o Type D.
Answer: o Type A
◉ A nurse practitioner would prescribe the liquid form of ibuprofen for
a six-year-old because:
o Drugs given in liquid form are less irritating to the stomach.
o A six-year-old may have problems swallowing a pill.
o Liquid forms of medication eliminate the concern for first-pass effect.
, o Liquid ibuprofen does not have to be dosed as often as tablet form..
Answer: o A six-year-old may have problems swallowing a pill.
◉ The role of the nurse practitioner in the use of herbal medication is to:
o Maintain competence in the prescribing of common herbal remedies.
o Recommend common OTC herbs to patients.
o Educate patients and guide them to appropriate sources of care.
o Encourage patients to not use herbal therapy due to the documented
dangers..
Answer: o Educate patients and guide them to appropriate sources of
care.
◉ Genetic polymorphisms account for differences in metabolism,
including:
o Poor metabolizers (PMs) that lack a working enzyme
o Intermediate metabolizers (IMs) that have one working, wild-type
allele and one mutant allele
o Extensive metabolizers (EMs), with two normally functioning alleles
o All of the above.
Answer: o All of the above
◉ The elderly are at high risk of ADRs due to:
