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WGU D236 Pathophysiology Objective Assessment Exam Questions & Correct Answers With Verified Solutions | Latest Update 2026/2027 | Graded A + | Guaranteed Pass!!

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WGU D236 Pathophysiology Objective Assessment Exam Questions & Correct Answers With Verified Solutions | Latest Update 2026/2027 | Graded A + | Guaranteed Pass!! High-yield systems: Cardiovascular, Respiratory, Neuro, Renal, Endocrine, GI, Immunity, Oncology, Hematology, Reproduction, Musculoskeletal, Fluids/Electrolytes, Acid–Base, Genetics **1. A patient with left-sided heart failure most likely presents with which symptom?** A. Peripheral edema B. Jugular venous distention C. Pulmonary crackles D. Hepatosplenomegaly **Answer: C** **2. Which electrolyte imbalance is most associated with Trousseau and Chvostek signs?** A. Hyperkalemia B. Hypercalcemia C. Hypocalcemia D. Hypernatremia **Answer: C** **3. A patient with COPD retains CO₂. Which acid–base imbalance is expected?** A. Respiratory alkalosis B. Respiratory acidosis C. Metabolic acidosis D. Metabolic alkalosis **Answer: B** **5. What is the primary cause of myocardial infarction?** A. Viral myocarditis B. Coronary artery rupture C. Atherosclerotic plaque rupture with thrombosis D. Hypertrophic cardiomyopathy **Answer: C** **6. A patient with chronic kidney disease presents with anemia due to lack of:** A. Erythropoietin B. Platelets C. Albumin D. Renin **Answer: A** **8. Wheezing in asthma is caused by:** A. Alveolar collapse B. Bronchoconstriction C. Pleural effusion D. Pulmonary fibrosis **Answer: B** **11. A patient with liver cirrhosis develops ascites due to:** A. Hypernatremia B. Increased albumin C. Portal hypertension D. Excess aldosterone **Answer: C** **12. Which respiratory finding indicates pneumothorax?** A. Bilateral crackles B. Trachea midline C. Absent breath sounds on one side D. Hyperresonance on both lungs **Answer: C** **13. Cushing’s syndrome is associated with:** A. Low cortisol B. High cortisol C. Low aldosterone D. Low catecholamines **Answer: B** **14. A major risk factor for venous thromboembolism is:** A. High HDL B. Immobility C. Increased mobility D. Low blood viscosity **Answer: B** **15. Which heart valve is most commonly affected by stenosis?** A. Tricuspid B. Pulmonic C. Aortic D. Mitral **Answer: C** **16. An early sign of hypoxia is:** A. Cyanosis B. Bradycardia C. Restlessness D. Hypotension **Answer: C** **17. Rheumatoid arthritis is best classified as:** A. Infectious arthritis B. Degenerative arthritis C. Autoimmune inflammatory disease D. Metabolic disease **Answer: C** **7. Which condition develops from destruction of β-cells in the pancreas?** A. Type 1 DM B. Type 2 DM C. Cushing’s syndrome D. Addison’s disease **Answer: A**

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WGU D236 Pathophysiology Objective Assessment
Exam Questions & Correct Answers With Verified
Solutions | Latest Update 2026/2027 | Graded A + |
Guaranteed Pass!!

✔ High-yield systems: Cardiovascular, Respiratory, Neuro, Renal, Endocrine,
GI,
Immunity, Oncology, Hematology, Reproduction, Musculoskeletal,
Fluids/Electrolytes, Acid–Base, Genetics



**1. A patient with left-sided heart failure most likely presents with which
symptom?**
A. Peripheral edema
B. Jugular venous distention
C. Pulmonary crackles
D. Hepatosplenomegaly
**Answer: C**

**2. Which electrolyte imbalance is most associated with Trousseau and
Chvostek signs?**
A. Hyperkalemia
B. Hypercalcemia C. Hypocalcemia
D. Hypernatremia
**Answer: C**

**3. A patient with COPD retains CO₂. Which acid–base imbalance is
expected?**
A. Respiratory alkalosis
B. Respiratory acidosis
C. Metabolic acidosis
D. Metabolic alkalosis

,**Answer: B**



**5. What is the primary cause of myocardial infarction?**
A. Viral myocarditis
B. Coronary artery rupture
C. Atherosclerotic plaque rupture with thrombosis
D. Hypertrophic cardiomyopathy
**Answer: C**

**6. A patient with chronic kidney disease presents with anemia due to lack
of:**
A. Erythropoietin
B. Platelets
C. Albumin
D. Renin
**Answer: A**
**8. Wheezing in asthma is caused by:**
A. Alveolar collapse
B. Bronchoconstriction
C. Pleural effusion
D. Pulmonary fibrosis
**Answer: B**

**11. A patient with liver cirrhosis develops ascites due to:**
A. Hypernatremia
B. Increased albumin
C. Portal hypertension
D. Excess aldosterone
**Answer: C**

**12. Which respiratory finding indicates pneumothorax?**
A. Bilateral crackles

,B. Trachea midline
C. Absent breath sounds on one side
D. Hyperresonance on both lungs
**Answer: C**


**13. Cushing’s syndrome is associated with:**
A. Low cortisol
B. High cortisol
C. Low aldosterone
D. Low catecholamines
**Answer: B**

**14. A major risk factor for venous thromboembolism is:**
A. High HDL
B. Immobility
C. Increased mobility
D. Low blood viscosity
**Answer: B**

**15. Which heart valve is most commonly affected by stenosis?**
A. Tricuspid
B. Pulmonic
C. Aortic
D. Mitral
**Answer: C**

**16. An early sign of hypoxia is:**
A. Cyanosis
B. Bradycardia
C. Restlessness
D. Hypotension
**Answer: C**

, **17. Rheumatoid arthritis is best classified as:**
A. Infectious arthritis
B. Degenerative arthritis
C. Autoimmune inflammatory disease
D. Metabolic disease
**Answer: C**




**7. Which condition develops from destruction of β-cells in the pancreas?**
A. Type 1 DM
B. Type 2 DM
C. Cushing’s syndrome
D. Addison’s disease
**Answer: A**

**4. Which hormone is deficient in Type 1 diabetes mellitus?**
A. Cortisol
B. Glucagon
C. Aldosterone
D. Insulin
**Answer: D**




**9. The hallmark of septic shock is:**
A. Hypertension
B. Increased afterload
C. Massive vasodilation
D. Bradycardia
**Answer: C**

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