Chamberlain University
NR 546 / NR546
Week 8
Neurotransmitter Table
Course: Advanced Pharmacology
, Carolyne
Nchabera
Neurotransmitter Table
* To be completed throughout course and submitted in Week 8*
Neuro Receptor Location/Function/Effects Distribution Drug classes that Specific medications that target this
transmitter Subtype /symptoms of excess or (ie: CNS/PNS, target this neurotransmitter or receptor
deficit if applicable GI, vascular) neurotransmitter or
receptor
Glutamate AMPA Ligand-gated ion channels CNS NMDA glutamate Memantine
Modulates cell excitability antagonist PCP
by allowing the flow of Barbiturates Ketamine
calcium and sodium ions Antiepileptics Dextromethorphan
into the cell. Dextromethadone
Located at the CNS in Parampanel
neurons and glia.
Excess has resulted in
schizophrenia, epilepsy,
and mania.
NMDA Ligand-gated ion channels, CNS NMDA receptor Memantine
strengthens synapses and is antagonist Amantadine
involved in strong Antipsychotics Ketamine
memory formation. Loop Diuretics Dextromethorphan
Excess is associated with Opiates Methadone
memory and learning Antidepressants Dextropropoxyphene
impairments, psychosis, Ketobemidone
and excitotoxic brain Furosemide
injury. Haldol
Tramadol
GABA GABA a Ligand-gated ion channels CNS Benzodiazepines Lorazepam, Clonazepam, Alprazolam
Functions as postsynaptic Limbic system Hypnotics Zolpidem, Zopiclone, zaleplon
inhibition by CI-influx Striatum Neuroactive steroids Allopregnanolone
Inotropic receptor Medulla
Reduces fear, anxiety, and Spinal Cord
Downloaded by Benjamin Luca ()
NR 546 / NR546
Week 8
Neurotransmitter Table
Course: Advanced Pharmacology
, Carolyne
Nchabera
Neurotransmitter Table
* To be completed throughout course and submitted in Week 8*
Neuro Receptor Location/Function/Effects Distribution Drug classes that Specific medications that target this
transmitter Subtype /symptoms of excess or (ie: CNS/PNS, target this neurotransmitter or receptor
deficit if applicable GI, vascular) neurotransmitter or
receptor
Glutamate AMPA Ligand-gated ion channels CNS NMDA glutamate Memantine
Modulates cell excitability antagonist PCP
by allowing the flow of Barbiturates Ketamine
calcium and sodium ions Antiepileptics Dextromethorphan
into the cell. Dextromethadone
Located at the CNS in Parampanel
neurons and glia.
Excess has resulted in
schizophrenia, epilepsy,
and mania.
NMDA Ligand-gated ion channels, CNS NMDA receptor Memantine
strengthens synapses and is antagonist Amantadine
involved in strong Antipsychotics Ketamine
memory formation. Loop Diuretics Dextromethorphan
Excess is associated with Opiates Methadone
memory and learning Antidepressants Dextropropoxyphene
impairments, psychosis, Ketobemidone
and excitotoxic brain Furosemide
injury. Haldol
Tramadol
GABA GABA a Ligand-gated ion channels CNS Benzodiazepines Lorazepam, Clonazepam, Alprazolam
Functions as postsynaptic Limbic system Hypnotics Zolpidem, Zopiclone, zaleplon
inhibition by CI-influx Striatum Neuroactive steroids Allopregnanolone
Inotropic receptor Medulla
Reduces fear, anxiety, and Spinal Cord
Downloaded by Benjamin Luca ()
