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Q1. What does a positive posterior drawer sign in a 10-year-old soccer player
signify?
A. Normal knee
B. Instability of the knee
C. Swelling on the knee
D. Injury to the meniscus
Correct Answer: B. Instability of the knee
Detailed Rationale: The posterior drawer test is used to identify mediolateral or
anteroposterior plane instability of the knee. The test is performed on both the
unaffected and affected knee for comparison. The anterior drawer test evaluates
the anterior cruciate ligament (ACL), while the posterior drawer test evaluates the
posterior cruciate ligament (PCL). To perform the test, the patient lies supine with
the knee at 90-degree flexion. The clinician grasps the posterior aspect of the tibia
over the upper calf muscle and, with steady force, pushes the lower leg backward.
Posterior movement indicates PCL injury and knee instability. Swelling and
meniscus injuries do not directly cause a positive drawer sign.
,Q2. A patient injures an ankle while playing soccer and reports rolling the foot
inward while falling, with immediate pain and swelling of the lateral part of the
joint. The patient is able to bear weight and denies hearing an audible sound at
the time of injury. What does this history indicate?
A. Likely ankle sprain with a possible fracture
B. Mild ankle injury without fracture
C. Mild soft tissue injury only
D. Serious ankle injury with certain fracture
Correct Answer: A. Likely ankle sprain with a possible fracture
Detailed Rationale: Immediate swelling of the joint raises the index of suspicion
for a fracture, even if the patient can bear weight. The mechanism described—
rolling the foot inward (inversion)—is classic for lateral ankle sprain affecting the
anterior talofibular ligament. However, the Ottawa Ankle Rules indicate that
immediate swelling and tenderness over the lateral malleolus warrant imaging to
rule out fracture. Inability to bear weight immediately after injury and bone
tenderness are predictors of fracture. This patient requires ankle X-rays to
definitively rule out fracture before diagnosing a simple sprain.
Q3. Which of the following statements is true regarding oral contraceptives?
A. Because oral contraceptives may cause harm to the fetus, they are pregnancy
category X drugs in pregnancy.
B. Oral contraceptives are linked to the promotion of ovarian, endometrial, and
breast cancer.
C. By increasing angiotensin and aldosterone, oral contraceptives may increase
blood pressure.
D. Oral contraceptives may reduce the risk of ovarian and endometrial cancers.
,Correct Answer: D. Oral contraceptives may reduce the risk of ovarian and
endometrial cancers.
Detailed Rationale: Combined oral contraceptives (COCs) provide protective
benefits against ovarian and endometrial cancers, with risk reduction lasting for
years after discontinuation. They are not pregnancy category X (rather, they are
contraindicated in pregnancy but category X indicates proven fetal risk). COCs do
not increase angiotensin and aldosterone; estrogen component increases hepatic
synthesis of angiotensinogen, leading to increased angiotensin II and potential
blood pressure elevation in susceptible women—but the mechanism is not through
direct aldosterone increase. Regarding cancer risk: COCs may slightly increase
breast and cervical cancer risk with long-term use, but they reduce ovarian and
endometrial cancer risk.
Q4. What is the single most important factor in determining whether a patient
with community-acquired pneumonia (CAP) requires hospitalization?
A. White blood cell count
B. CURB-65 score
C. Oxygen saturation
D. Presence of pleuritic chest pain
Correct Answer: B. CURB-65 score
Detailed Rationale: The CURB-65 scoring system (Confusion, Uremia [BUN >19
mg/dL], Respiratory rate ≥30/min, low Blood pressure [SBP <90 or DBP ≤60], age
≥65 years) is the most validated and clinically useful tool for determining CAP
severity and need for hospitalization. A score of 0-1 suggests outpatient treatment;
2 indicates brief hospitalization; 3-5 requires intensive care. While oxygen
, saturation and WBC count provide useful information, the CURB-65 score
integrates multiple clinical factors into an evidence-based decision tool.
Q5. A 55-year-old patient with type 2 diabetes presents with new-onset right
foot pain, erythema, and swelling for 2 days. The patient denies trauma. What
is the most appropriate initial diagnostic test?
A. Serum uric acid level
B. Plain radiograph of the foot
C. Ultrasound of the foot
D. Erythrocyte sedimentation rate (ESR)
Correct Answer: B. Plain radiograph of the foot
Detailed Rationale: Plain radiography is the initial imaging study of choice for any
diabetic patient presenting with a red, swollen foot, even without trauma, to
evaluate for Charcot neuroarthropathy or osteomyelitis. Charcot foot begins with
acute inflammation (warmth, erythema, edema) and must be distinguished from
cellulitis or gout. X-rays show early changes (soft tissue swelling, joint subluxation)
and late findings (fragmentation, dislocation). Serum uric acid may help rule out
gout but is not first-line. Ultrasound has limited utility in Charcot evaluation. ESR is
non-specific and does not differentiate causes of inflammation.
Q6. Which medication class is first-line for the treatment of generalized
anxiety disorder (GAD) in an otherwise healthy adult?
A. Benzodiazepines
B. Buspirone