DISEASE Exam Questions
with Answers
User [Date] [Course title]
,Sporadic - Correct Answer: are disease that occur occasionally and irregularly within specific pattern
Epidemic - Correct Answer: are disease that occur in a greater number than what is expected in a
specific are over a specific time
Endemic - Correct Answer: are those that are present in a population or community at times, usually
involve people during specific periods.
pandemic - Correct Answer: an epidemic that affects several countries or continents. Current examples
are AIDS/HIV and COVID 19
Mycobacterium tuberculosis - Correct Answer: Tuberculosis (TB)is an infectious disease caused by the
bacteria called
Tuberculosis (TB - Correct Answer: It is transmitted from a TB patient to another person through
coughing, sneezing and spitting. Thus, close contacts, especially household members, could be infected
with TB.
Mycobacterium tuberculosis, Mycobacterium Africanum and Mycobacterium bovis (from cattle) -
Correct Answer: biologic agents of TB
Mycobacterium bovis (from cattle), - Correct Answer: an acid fast aerobic organism(hence targets the
highly oxygenated alveolar area. ) causative agent of TB
TB - Correct Answer: * Primary Complex in children is not contagious
3-8 weeks - Correct Answer: incubation period of TB
BCG (Bacillus Calmette-Guerin)Vaccination of newborn, infants and school entrants. Ideally given at
birth. If given 12 months , do PPD, give BCG if negative. - Correct Answer: prevention against TB
, 1. Sputum smear and culture confirms the diagnosis (definitive test). 2. Tuberculin Test (Mantoux
Test)detects the presence of antibodies * Results within 48-72 hours from skin testing, possible if with
induration of 10 mm or more * If less than 5 years old, and for (+)BCG, 10mm is positive * If more than 5
years old, and for (-) BCG., More than 5mm is positive 3. Chest X-ray determines the presence and
extent of disease - Correct Answer: diagnosis of TB
TB - Correct Answer: Granuloma leads to necrosis, then liquefaction, sloughing and cavitation
TB - Correct Answer: signs and symptoms include Fatigue: weight loss; persistent low grade afternoon
fever; night sweats and chills; hemoptysis; productive cough; pleuritic chest pain
Rifampicin - Correct Answer: Orange discoloration
Rifampicin - Correct Answer: Best taken on empty stomach, but causes gastric irritation hence should be
taken with food (also at bedtime)
Rifampicin and pyrazinamide - Correct Answer: Protect drug form light
isoniazid - Correct Answer: Hepatic enzyme elevation, peripheral neuropathy as it competes with
absorption of vit.B6 or pyridoxine
isoniazid - Correct Answer: Take before meals
isoniazid - Correct Answer: 10-50mg pyridoxine as prophylaxis, 50- 100 mg as treatment
Pyrazinamide (PZA) - Correct Answer: Rapidly bacteriostatic and slowly bactericida
Pyrazinamide (PZA) - Correct Answer: Hepatotoxic, ototoxic, nephrotoxic, GI upset
Pyrazinamide (PZA) - Correct Answer: May lead to hyperuricemia. Arthralgia (shoulder