Questions and Answers | Newest Study
Guide with Solutions | Grade A+
• Antacid -✓✓Condition: GERD | Medication (Generic): Calcium carbonate | Mechanism
of Action: Neutralizes gastric acid | Indication / Use: Mild intermittent GERD | Adult
Dose: 500-1000 mg PRN | Duration: PRN | Key Adverse Effects: Co
• Alginic acid -✓✓Condition: GERD | Medication (Generic): Alginic acid + antacid |
Mechanism of Action: Forms raft barrier | Indication / Use: Postprandial reflux | Adult
Dose: Per label | Duration: PRN | Key Adverse Effects: Bloating | Contraind
• H2 receptor antagonist -✓✓Condition: GERD | Medication (Generic): Famotidine |
Mechanism of Action: Blocks H2 receptors | Indication / Use: Mild/nocturnal GERD |
Adult Dose: 20 mg BID | Duration: 4-8 wks | Key Adverse Effects: Headache | Contrai
• Proton pump inhibitor -✓✓Condition: GERD | Medication (Generic): Omeprazole |
Mechanism of Action: Inhibits H+/K+ ATPase | Indication / Use: First-line GERD | Adult
Dose: 20-40 mg daily | Duration: 4-8 wks | Key Adverse Effects: C. diff, fractures |
• Prokinetic -✓✓Condition: GERD | Medication (Generic): Metoclopramide | Mechanism
of Action: ↑ gastric emptying | Indication / Use: Refractory GERD | Adult Dose: 5-10 mg
QID | Duration: Short-term | Key Adverse Effects: EPS, TD | Cont
• GABA-B agonist -✓✓Condition: GERD | Medication (Generic): Baclofen | Mechanism
of Action: ↓ LES relaxations | Indication / Use: Refractory GERD | Adult Dose: 5-20 mg
TID | Duration: Chronic | Key Adverse Effects: Sedation | Contraindication
• Mucosal protectant -✓✓Condition: GERD | Medication (Generic): Sucralfate |
Mechanism of Action: Protective barrier | Indication / Use: Adjunct/alt GERD | Adult
Dose: 1 g QID | Duration: 4-8 wks | Key Adverse Effects: Constipation | Contraindication
• Triple therapy -✓✓Condition: H. pylori | Medication (Generic): Clarithromycin +
Amoxicillin + PPI | Mechanism of Action: Eradicates H. pylori | Indication / Use:
Clarithromycin triple | Adult Dose: Standard dosing | Duration: 14 days | Key Adverse
• Quadruple therapy -✓✓Condition: H. pylori | Medication (Generic): Bismuth +
Metronidazole + Tetracycline + PPI | Mechanism of Action: Eradicates H. pylori |
Indication / Use: Bismuth quadruple | Adult Dose: Standard dosing | Duration: 10-14
days