COMPREHENSIVE COMMUNICATION
STUDIES QUESTIONS AND SOLUTIONS
◉ What antipsychotics are best for acute mania?.
Answer: Atypical antipsychotics
◉ Aripiprazole.
Answer: - 2nd generation for bipolar disorder
- best antipsychotic to use for bipolar
◉ Clozapine.
Answer: - effective for prophylaxis and acute mania
- causes agranulocytosis
◉ Which drugs cause agranulocytosis?.
Answer: Clozapine and Carbamazepine
◉ Olanzapine.
Answer: antipsychotic used for acute treatment of bipolar disorder
that may cause weight gain; 2nd generation
,◉ Quetiapine.
Answer: antipsychotic used for acute and rapid cycling mania; used
for sleep
◉ Risperidone.
Answer: used for acute bipolar disorder, also used for autism and
aggression/unrealistic thinking
◉ First line approach to bipolar disorder.
Answer: lithium or valproates
◉ Clozapine.
Answer: administer when WBC is greater than 2000
◉ Clozapine and Olanzapine.
Answer: - Atypical antipsychotics
- Causes metabolic syndrome (weight gain)
- use sunscreen
- immediately report sore throat, malice, fever, bleeding
- treats both negative and positive symptoms
, ◉ Chlorpromazine.
Answer: 1st antipsychotic
◉ Schizophrenia neurotransmitters.
Answer: Increase in dopamine and a decrease in acetylcholine
◉ Phases of Schizophrenia.
Answer: Acute- the patient experiences severe psychotic symptoms
Stabilizing- the patient is getting better
Stable- the patient might still experience hallucinations and
delusions, but they are not as severe or disabling as they were
during the acute phase and they can ignore them
◉ Positive symptoms.
Answer: - excessive dopamine; abnormal thoughts, agitation,
delusions, excitement, hallucinations, hostility, illusions, insomnia
- 1st generation antipsychotics are best to treat
◉ Negative symptoms.
Answer: - too little dopamine; alogia, anergia, attention deficits,
blunted affect, poor raport, poverty of speech
- 2nd generations are best to treat