Module 10 Female GU Study Guide
complete solutions.
Questions 1–20: Anatomy & Tanner Staging
1. At what Tanner stage does menarche most commonly occur?
A) Stage 2
B) Stage 3
C) Stage 4
D) Stage 5
Correct Answer: C
Rationale: Menarche most commonly occurs at Tanner Stage 4 (75% of females).
It is unusual before Stage 3. Stage 5 is post-menarcheal adult breast.
2. Which breast structure is most likely to harbor a palpable mass due to its
extension into the axilla?
A) Areola
B) Tail of Spence
C) Inframammary ridge
D) Lactiferous ducts
Correct Answer: B
Rationale: The Tail of Spence extends superolaterally into the axilla. It is a
common site for palpable breast masses and lymph nodes.
,3. A 12-year-old female presents with breast bud formation without areolar
enlargement. What Tanner stage is this?
A) Stage 1
B) Stage 2
C) Stage 3
D) Stage 4
Correct Answer: B
Rationale: Tanner Stage 2 is the breast bud stage: small mound of breast tissue
with enlargement of areola but no areolar mound separation.
4. Which finding is consistent with Tanner Stage 5 breast development?
A) Areola and breast form a single smooth contour
B) Areola is a secondary mound above the breast
C) Only the nipple projects forward
D) No palpable breast tissue
Correct Answer: A
Rationale: In Stage 5, the areola recesses to the general breast contour, leaving
only the nipple projecting. Stage 4 has the areola as a secondary mound.
5. A 14-year-old female is Tanner Stage 3 and asks when she will likely start her
period. What is your best estimate?
A) Within 1 month
B) Within 6 months
C) Within 2 years
,D) She already should have started
Correct Answer: C
Rationale: The average interval from Stage 2 to menarche is 2 years. Stage 3 is ~1
year after Stage 2, so menarche is typically ~1 more year away.
6. Which Tanner stage describes elevation of the areola as a secondary mound
above the breast?
A) Stage 2
B) Stage 3
C) Stage 4
D) Stage 5
Correct Answer: C
Rationale: Tanner Stage 4 is characterized by the areola and nipple forming a
secondary mound projecting above the breast contour.
7. What percentage of females have not yet reached menarche by Tanner Stage 4?
A) 0%
B) 10%
C) 25%
D) 50%
Correct Answer: C
Rationale: Approximately 75% of females have menarche by Stage 4, meaning
25% have not yet begun menstruation by Stage 4.
, 8. Which condition is associated with delayed puberty and webbed neck in a
female adolescent? A) Turner syndrome
B) Klinefelter syndrome
C) Graves’ disease
D) Polycystic ovary syndrome
Correct Answer: A
Rationale: Turner syndrome (45,XO) presents with short stature, webbed neck, low
hairline, and streak ovaries → delayed puberty/absent menarche.
9. During breast development, which change occurs first?
A) Menarche
B) Pubic hair
C) Thelarche (breast budding)
D) Axillary hair
Correct Answer: C
Rationale: Thelarche (breast budding, Tanner Stage 2) is the first sign of puberty in
females, occurring before pubic hair in most girls.
10. A 16-year-old has no breast development but has normal pubic hair. What is
the most likely cause?
A) Normal variation
B) Androgen insensitivity syndrome
C) Turner syndrome
D) Hypothyroidism