NR 566 MIDTERM NR566 MIDTERM
EXAM QUESTIONS AND ANSWERS | 2026
UPDATE | 100% CORRECT.
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk? -
ANS Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? - ANS -Promote weight loss
by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the
availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? - ANS 3
months or less
What drug schedule are Phentermine and Diethylpropion under? - ANS Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What condition should
we screen for? - ANS -baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - ANS -increase HR and BP
-dry mouth and constipation
@COPYRIGHT ALL RIGHTS RESERVED PAGE 1 OF 34
,What is role of topiramate in weight loss? - ANS Increases satiety
What are some Phentermine/topiramate contraindications for use? - ANS not approved in
children and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid insomnia? -
ANS given before 1600
What are some high-risk patient conditions that we should use Phentermine/topiramate with
caution? - ANS hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects - ANS insomnia, nervousness, anxiety, depression,
blurred vision
Which of the following would be a contraindication to prescribing phentermine/topiramate?
Select all that apply. - ANS A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by 30%. -
ANS GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may not be
absorbed well when taking Orlistat. - ANS 2
@COPYRIGHT ALL RIGHTS RESERVED PAGE 2 OF 34
,Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. - ANS 12
Orlistat results in the least amount of weight loss of all. How much? - ANS 2-3% body weight
(7 lbs in year)
Orlistat adverse effects - ANS Fecal incontinence, oily rectal leakage, flatus, abdominal
cramps. liver damage (light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - ANS In those with malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially if the patient
is on coumadin? - ANS Monitor Coumadin as Vitamin K deficiency may occur and intensify
effect of Coumadin.
A patient with a BMI of 27 would be considered: - ANS overweight
Lorcaserin adverse effects - ANS headache, URI, back pain, hypoglycemia (in DM), blood
dyscrasias, cognitive impairment, psychiatric disorders, priapism, pulmonary hypertension, and
valvular heart disease
Lorcaserin MOA - ANS Reduces waist circumference, fasting glucose, insulin, total cholesterol,
LDL, triglycerides
When is Lorcaserin contraindicated? - ANS CrCl <30
-Not approved in children
Lorcaserin drug interactions - ANS -MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning - ANS increased risk for suicidal ideation and
suicide attempts in children, adolescents, and young adults
@COPYRIGHT ALL RIGHTS RESERVED PAGE 3 OF 34
, Do not take Naltrexone and Bupropion within ___weeks of taking a _____. - ANS -two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what? -
ANS opioids
Naltrexone and Bupropion contraindications - ANS HTN, seizure disorders, eating disorders,
alcohol or drug withdrawal
Liraglutide MOA - ANS -promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm - ANS 10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes - ANS hypoglycemia
Baseline labs for Liraglutide - ANS lipids, CMP, HgA1C q 6 months, triglycerides
Liraglutide black box warning - ANS associated with a risk for thyroid C-cell tumors based on
studies in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2 (MEN 2) or
personal/family history of medullary thyroid carcinoma
Those trying to LOSE weight should exercise at least ____ min/week or more - ANS 150
What BMI is bariatric surgery considered? - ANS 35 or more
@COPYRIGHT ALL RIGHTS RESERVED PAGE 4 OF 34
EXAM QUESTIONS AND ANSWERS | 2026
UPDATE | 100% CORRECT.
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk? -
ANS Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? - ANS -Promote weight loss
by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the
availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? - ANS 3
months or less
What drug schedule are Phentermine and Diethylpropion under? - ANS Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What condition should
we screen for? - ANS -baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - ANS -increase HR and BP
-dry mouth and constipation
@COPYRIGHT ALL RIGHTS RESERVED PAGE 1 OF 34
,What is role of topiramate in weight loss? - ANS Increases satiety
What are some Phentermine/topiramate contraindications for use? - ANS not approved in
children and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid insomnia? -
ANS given before 1600
What are some high-risk patient conditions that we should use Phentermine/topiramate with
caution? - ANS hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects - ANS insomnia, nervousness, anxiety, depression,
blurred vision
Which of the following would be a contraindication to prescribing phentermine/topiramate?
Select all that apply. - ANS A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by 30%. -
ANS GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may not be
absorbed well when taking Orlistat. - ANS 2
@COPYRIGHT ALL RIGHTS RESERVED PAGE 2 OF 34
,Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. - ANS 12
Orlistat results in the least amount of weight loss of all. How much? - ANS 2-3% body weight
(7 lbs in year)
Orlistat adverse effects - ANS Fecal incontinence, oily rectal leakage, flatus, abdominal
cramps. liver damage (light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - ANS In those with malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially if the patient
is on coumadin? - ANS Monitor Coumadin as Vitamin K deficiency may occur and intensify
effect of Coumadin.
A patient with a BMI of 27 would be considered: - ANS overweight
Lorcaserin adverse effects - ANS headache, URI, back pain, hypoglycemia (in DM), blood
dyscrasias, cognitive impairment, psychiatric disorders, priapism, pulmonary hypertension, and
valvular heart disease
Lorcaserin MOA - ANS Reduces waist circumference, fasting glucose, insulin, total cholesterol,
LDL, triglycerides
When is Lorcaserin contraindicated? - ANS CrCl <30
-Not approved in children
Lorcaserin drug interactions - ANS -MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning - ANS increased risk for suicidal ideation and
suicide attempts in children, adolescents, and young adults
@COPYRIGHT ALL RIGHTS RESERVED PAGE 3 OF 34
, Do not take Naltrexone and Bupropion within ___weeks of taking a _____. - ANS -two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what? -
ANS opioids
Naltrexone and Bupropion contraindications - ANS HTN, seizure disorders, eating disorders,
alcohol or drug withdrawal
Liraglutide MOA - ANS -promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm - ANS 10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes - ANS hypoglycemia
Baseline labs for Liraglutide - ANS lipids, CMP, HgA1C q 6 months, triglycerides
Liraglutide black box warning - ANS associated with a risk for thyroid C-cell tumors based on
studies in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2 (MEN 2) or
personal/family history of medullary thyroid carcinoma
Those trying to LOSE weight should exercise at least ____ min/week or more - ANS 150
What BMI is bariatric surgery considered? - ANS 35 or more
@COPYRIGHT ALL RIGHTS RESERVED PAGE 4 OF 34
